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Questions and Answers
A patient presents with end-stage renal disease and severely elevated potassium levels unresponsive to conventional treatments. What is the most appropriate next step in management?
A patient presents with end-stage renal disease and severely elevated potassium levels unresponsive to conventional treatments. What is the most appropriate next step in management?
- Loop diuretic administration
- Dietary potassium restriction
- Sodium bicarbonate administration
- Dialysis (correct)
Which of the following represents the best initial treatment strategy for a patient diagnosed with stage 1 chronic kidney disease accompanied by proteinuria?
Which of the following represents the best initial treatment strategy for a patient diagnosed with stage 1 chronic kidney disease accompanied by proteinuria?
- Angiotensin-converting enzyme (ACE) inhibitor therapy (correct)
- High-dose steroid therapy
- Calcium channel blocker therapy
- Aggressive diuretic therapy
Analysis of a patient's kidney stone reveals that it is primarily composed of which of the following, representing the most common cause of nephrolithiasis?
Analysis of a patient's kidney stone reveals that it is primarily composed of which of the following, representing the most common cause of nephrolithiasis?
- Cystine stones
- Uric acid crystals
- Struvite stones
- Calcium oxalate crystals (correct)
A 45-year-old woman with a history of systemic lupus erythematosus develops new onset proteinuria and hematuria. Which of the following renal conditions is most likely?
A 45-year-old woman with a history of systemic lupus erythematosus develops new onset proteinuria and hematuria. Which of the following renal conditions is most likely?
In a patient with chronic kidney disease, which of the following clinical findings is the clearest indication for initiating dialysis?
In a patient with chronic kidney disease, which of the following clinical findings is the clearest indication for initiating dialysis?
Which of the following etiologies is the most common culprit behind nephrogenic diabetes insipidus?
Which of the following etiologies is the most common culprit behind nephrogenic diabetes insipidus?
A 25-year-old female with recurrent UTIs presents with hematuria. Urinalysis reveals RBC casts. What is the most likely underlying cause?
A 25-year-old female with recurrent UTIs presents with hematuria. Urinalysis reveals RBC casts. What is the most likely underlying cause?
Which of the following metabolic derangements is a well-recognized complication of nephrotic syndrome?
Which of the following metabolic derangements is a well-recognized complication of nephrotic syndrome?
A patient's lab results indicate elevated levels of homocysteine and methylmalonic acid. Which condition does this most likely suggest?
A patient's lab results indicate elevated levels of homocysteine and methylmalonic acid. Which condition does this most likely suggest?
A hematologist is reviewing a patient's bone marrow sample and identifies the Philadelphia chromosome. Which hematologic malignancy is most closely associated with this genetic abnormality?
A hematologist is reviewing a patient's bone marrow sample and identifies the Philadelphia chromosome. Which hematologic malignancy is most closely associated with this genetic abnormality?
A doctor notices a sharp drop in a hospitalized patient's platelet count after the administration of heparin. What condition should the doctor suspect?
A doctor notices a sharp drop in a hospitalized patient's platelet count after the administration of heparin. What condition should the doctor suspect?
A patient presents with bone pain, elevated calcium levels, and impaired kidney function. Further testing reveals an M-protein spike. Which condition is most likely?
A patient presents with bone pain, elevated calcium levels, and impaired kidney function. Further testing reveals an M-protein spike. Which condition is most likely?
Genetic testing confirms a mutation leading to excessive iron absorption in a patient. What is the most probable primary cause of their iron overload?
Genetic testing confirms a mutation leading to excessive iron absorption in a patient. What is the most probable primary cause of their iron overload?
A 55-year-old male with a history of excessive alcohol consumption exhibits bleeding gums and a low platelet count. How does cirrhosis contribute to thrombocytopenia in this patient?
A 55-year-old male with a history of excessive alcohol consumption exhibits bleeding gums and a low platelet count. How does cirrhosis contribute to thrombocytopenia in this patient?
A patient is diagnosed with myelodysplastic syndrome (MDS). Which of the following is a key characteristic that differentiates MDS from other bone marrow disorders?
A patient is diagnosed with myelodysplastic syndrome (MDS). Which of the following is a key characteristic that differentiates MDS from other bone marrow disorders?
Which of the following factors associated with increased deep vein thrombosis (DVT) risk is most directly linked to impaired venous return?
Which of the following factors associated with increased deep vein thrombosis (DVT) risk is most directly linked to impaired venous return?
A patient presents with a chronic cough and sputum production for at least three months of the year for two consecutive years. Which condition is the most likely diagnosis?
A patient presents with a chronic cough and sputum production for at least three months of the year for two consecutive years. Which condition is the most likely diagnosis?
Which pulmonary function test finding is most indicative of asthma?
Which pulmonary function test finding is most indicative of asthma?
A 60-year-old patient with a history of heavy smoking presents with new onset hemoptysis, unexplained weight loss and a persistent cough. Which of the following is the most likely diagnosis?
A 60-year-old patient with a history of heavy smoking presents with new onset hemoptysis, unexplained weight loss and a persistent cough. Which of the following is the most likely diagnosis?
What is the most common causative organism in community-acquired pneumonia?
What is the most common causative organism in community-acquired pneumonia?
A patient with known asthma experiences acute shortness of breath, wheezing, and chest tightness following exposure to cat dander. What is the MOST appropriate initial treatment?
A patient with known asthma experiences acute shortness of breath, wheezing, and chest tightness following exposure to cat dander. What is the MOST appropriate initial treatment?
Which of the following is the strongest risk factor for the development of pulmonary embolism?
Which of the following is the strongest risk factor for the development of pulmonary embolism?
A 65-year-old patient with a 45-pack-year smoking history presents with progressive dyspnea on exertion. Examination reveals a barrel chest and decreased breath sounds bilaterally. Which of the following is the most likely diagnosis?
A 65-year-old patient with a 45-pack-year smoking history presents with progressive dyspnea on exertion. Examination reveals a barrel chest and decreased breath sounds bilaterally. Which of the following is the most likely diagnosis?
For acute exacerbations of COPD, which intervention is most important to improve airflow and oxygenation?
For acute exacerbations of COPD, which intervention is most important to improve airflow and oxygenation?
A patient's chest X-ray reveals a mass located in the apex of the lung. While other conditions are possible, what primary diagnosis should be considered?
A patient's chest X-ray reveals a mass located in the apex of the lung. While other conditions are possible, what primary diagnosis should be considered?
Which histological type of lung cancer is most frequently observed in individuals who have never smoked?
Which histological type of lung cancer is most frequently observed in individuals who have never smoked?
A 50-year-old woman with a history of asthma reports increased difficulty breathing and wheezing. Which action is the most appropriate initial step in her management?
A 50-year-old woman with a history of asthma reports increased difficulty breathing and wheezing. Which action is the most appropriate initial step in her management?
A patient experiences a sudden onset of sharp chest pain that intensifies with inspiration. Physical examination reveals tenderness over the rib cage. Which condition is the most likely cause?
A patient experiences a sudden onset of sharp chest pain that intensifies with inspiration. Physical examination reveals tenderness over the rib cage. Which condition is the most likely cause?
A 40-year-old male with chronic asthma experiences progressively worsening dyspnea, cough, and wheezing. What is the most probable underlying cause?
A 40-year-old male with chronic asthma experiences progressively worsening dyspnea, cough, and wheezing. What is the most probable underlying cause?
A 25-year-old woman presents with a persistent dry cough and malaise after a recent visit to a farm. Which condition should be prioritized in the differential diagnosis?
A 25-year-old woman presents with a persistent dry cough and malaise after a recent visit to a farm. Which condition should be prioritized in the differential diagnosis?
A 65-year-old male with a history of smoking and COPD presents with a new productive cough, fever, and pleuritic chest pain. A chest X-ray shows consolidation in the lower lobe. What is the most likely diagnosis?
A 65-year-old male with a history of smoking and COPD presents with a new productive cough, fever, and pleuritic chest pain. A chest X-ray shows consolidation in the lower lobe. What is the most likely diagnosis?
What pulmonary function test finding is typically observed in a patient with restrictive lung disease, reflecting the reduced lung volume?
What pulmonary function test finding is typically observed in a patient with restrictive lung disease, reflecting the reduced lung volume?
A patient's chest X-ray reveals a cavitary lesion in the upper lobe. While tuberculosis is a primary concern, what other condition can present with similar radiographic findings and should be considered in the differential diagnosis?
A patient's chest X-ray reveals a cavitary lesion in the upper lobe. While tuberculosis is a primary concern, what other condition can present with similar radiographic findings and should be considered in the differential diagnosis?
A patient develops pneumonia 48 hours after being admitted to the hospital. Pseudomonas aeruginosa is a common cause; however, what patient-related risk factor most significantly increases the likelihood of this specific infection over other hospital-acquired pneumonias?
A patient develops pneumonia 48 hours after being admitted to the hospital. Pseudomonas aeruginosa is a common cause; however, what patient-related risk factor most significantly increases the likelihood of this specific infection over other hospital-acquired pneumonias?
Polysomnography is the primary diagnostic test for obstructive sleep apnea. Beyond identifying apneas, what crucial information does polysomnography provide that is essential for determining the severity and guiding treatment?
Polysomnography is the primary diagnostic test for obstructive sleep apnea. Beyond identifying apneas, what crucial information does polysomnography provide that is essential for determining the severity and guiding treatment?
A 35-year-old woman presents with a non-productive cough, fatigue, and shortness of breath, with a history of exposure to bird droppings, suggesting hypersensitivity pneumonitis (HP). What is the most important next step in management after suspecting HP?
A 35-year-old woman presents with a non-productive cough, fatigue, and shortness of breath, with a history of exposure to bird droppings, suggesting hypersensitivity pneumonitis (HP). What is the most important next step in management after suspecting HP?
A patient with emphysema shows a flattened diaphragm on a chest X-ray. What physiological change directly leads to this radiographic finding?
A patient with emphysema shows a flattened diaphragm on a chest X-ray. What physiological change directly leads to this radiographic finding?
A patient with COPD presents with worsening dyspnea, increased sputum production, and purulent sputum, indicating a respiratory infection as the likely cause of acute exacerbation. Besides antibiotics, what is another crucial component in managing this acute exacerbation of COPD?
A patient with COPD presents with worsening dyspnea, increased sputum production, and purulent sputum, indicating a respiratory infection as the likely cause of acute exacerbation. Besides antibiotics, what is another crucial component in managing this acute exacerbation of COPD?
Digital clubbing is a common finding in patients with chronic pulmonary fibrosis. What pathophysiological mechanism is thought to be the primary cause of digital clubbing in this condition?
Digital clubbing is a common finding in patients with chronic pulmonary fibrosis. What pathophysiological mechanism is thought to be the primary cause of digital clubbing in this condition?
Rifampin and isoniazid are first-line treatments for active tuberculosis. What is a critical counseling point to emphasize to patients starting this regimen to minimize adverse effects?
Rifampin and isoniazid are first-line treatments for active tuberculosis. What is a critical counseling point to emphasize to patients starting this regimen to minimize adverse effects?
A 35-year-old man presents with a high fever, night sweats, and a productive cough with blood-streaked sputum for the past month. A chest X-ray shows upper lobe cavitary lesions. Which of the following is the most appropriate initial test for diagnosis?
A 35-year-old man presents with a high fever, night sweats, and a productive cough with blood-streaked sputum for the past month. A chest X-ray shows upper lobe cavitary lesions. Which of the following is the most appropriate initial test for diagnosis?
A 27-year-old woman presents with fever, headache, and a stiff neck. Lumbar puncture reveals an elevated white blood cell count, increased protein, and decreased glucose in cerebrospinal fluid. Which of the following is the most common cause of her condition in adults?
A 27-year-old woman presents with fever, headache, and a stiff neck. Lumbar puncture reveals an elevated white blood cell count, increased protein, and decreased glucose in cerebrospinal fluid. Which of the following is the most common cause of her condition in adults?
A 40-year-old man with poorly controlled diabetes presents with a rapidly spreading infection of the soft tissue in his leg, associated with crepitus and foul-smelling discharge. What is the most likely causative organism?
A 40-year-old man with poorly controlled diabetes presents with a rapidly spreading infection of the soft tissue in his leg, associated with crepitus and foul-smelling discharge. What is the most likely causative organism?
A patient with HIV presents with progressive confusion, focal neurological deficits, and seizures. MRI reveals multiple ring-enhancing lesions in the brain. Which of the following is the most likely diagnosis?
A patient with HIV presents with progressive confusion, focal neurological deficits, and seizures. MRI reveals multiple ring-enhancing lesions in the brain. Which of the following is the most likely diagnosis?
A 28-year-old woman presents with fever, malaise, pharyngitis, and posterior cervical lymphadenopathy. Monospot test is positive. Which of the following complications is most concerning in this patient?
A 28-year-old woman presents with fever, malaise, pharyngitis, and posterior cervical lymphadenopathy. Monospot test is positive. Which of the following complications is most concerning in this patient?
A 55-year-old male presents with sudden-onset high fever, hypotension, and purpura. He recently had a splenectomy after a motor vehicle accident. Blood cultures grow an encapsulated Gram-negative diplococcus. Which of the following pathogens is most likely responsible?
A 55-year-old male presents with sudden-onset high fever, hypotension, and purpura. He recently had a splenectomy after a motor vehicle accident. Blood cultures grow an encapsulated Gram-negative diplococcus. Which of the following pathogens is most likely responsible?
A patient presents with severe watery diarrhea after returning from a trip to South America. Which of the following is the most likely cause?
A patient presents with severe watery diarrhea after returning from a trip to South America. Which of the following is the most likely cause?
An elderly patient in a nursing home develops a cough, fever, and pleuritic chest pain. A chest X-ray shows a right lower lobe consolidation. Sputum Gram stain reveals Gram-positive cocci in pairs. What is the most likely causative organism?
An elderly patient in a nursing home develops a cough, fever, and pleuritic chest pain. A chest X-ray shows a right lower lobe consolidation. Sputum Gram stain reveals Gram-positive cocci in pairs. What is the most likely causative organism?
Flashcards
Vitamin B12 deficiency
Vitamin B12 deficiency
Elevated homocysteine and methylmalonic acid levels are indicative.
Chronic myelogenous leukemia (CML)
Chronic myelogenous leukemia (CML)
Characterized by the presence of the Philadelphia chromosome (BCR-ABL fusion gene).
Thrombocytopenia in hospitals
Thrombocytopenia in hospitals
Heparin-induced thrombocytopenia is a common cause.
Multiple myeloma hallmark
Multiple myeloma hallmark
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Iron overload cause
Iron overload cause
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Thrombocytopenia causes
Thrombocytopenia causes
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Myelodysplastic syndromes feature
Myelodysplastic syndromes feature
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Deep vein thrombosis (DVT) risk
Deep vein thrombosis (DVT) risk
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Dialysis
Dialysis
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ACE inhibitor
ACE inhibitor
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Calcium oxalate crystals
Calcium oxalate crystals
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Lupus nephritis
Lupus nephritis
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Fluid overload unresponsive to diuretics
Fluid overload unresponsive to diuretics
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Lithium toxicity
Lithium toxicity
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Glomerulonephritis
Glomerulonephritis
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Hyperlipidemia
Hyperlipidemia
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Chronic Bronchitis
Chronic Bronchitis
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Hallmark of Asthma
Hallmark of Asthma
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Lung Cancer Symptoms
Lung Cancer Symptoms
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Common Cause of Pneumonia
Common Cause of Pneumonia
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Acute Asthma Treatment
Acute Asthma Treatment
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Pulmonary Embolism Risk Factor
Pulmonary Embolism Risk Factor
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COPD Symptoms
COPD Symptoms
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COPD Exacerbation Treatment
COPD Exacerbation Treatment
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Lung mass diagnosis
Lung mass diagnosis
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Most common lung cancer in nonsmokers
Most common lung cancer in nonsmokers
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Asthma management step
Asthma management step
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Costochondritis symptoms
Costochondritis symptoms
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Acute asthma exacerbation
Acute asthma exacerbation
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Hypersensitivity pneumonitis
Hypersensitivity pneumonitis
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Pneumonia characteristics
Pneumonia characteristics
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Restrictive lung disease finding
Restrictive lung disease finding
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Cavitary lesion in lung
Cavitary lesion in lung
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Common cause of hospital-acquired pneumonia
Common cause of hospital-acquired pneumonia
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Primary test for obstructive sleep apnea
Primary test for obstructive sleep apnea
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Symptoms from bird droppings exposure
Symptoms from bird droppings exposure
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Emphysema hallmark X-ray finding
Emphysema hallmark X-ray finding
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Acute COPD exacerbation cause
Acute COPD exacerbation cause
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Finding in chronic pulmonary fibrosis
Finding in chronic pulmonary fibrosis
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First-line treatment for active tuberculosis
First-line treatment for active tuberculosis
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Osteoarthritis
Osteoarthritis
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Initial test for TB
Initial test for TB
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Common cause of meningitis in adults
Common cause of meningitis in adults
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Causative organism for necrotizing fasciitis
Causative organism for necrotizing fasciitis
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Diagnosis in HIV with brain lesions
Diagnosis in HIV with brain lesions
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Complication of mononucleosis
Complication of mononucleosis
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Pathogen post-splenectomy
Pathogen post-splenectomy
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Traveler's diarrhea
Traveler's diarrhea
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Study Notes
Cardiology
- Left-sided heart failure: Chronic hypertension is the most common cause.
- Chest pain, dyspnea, new murmur: Aortic stenosis is the likely diagnosis. Echocardiogram reveals left ventricular hypertrophy and aortic valve thickening.
- Fatigue, dyspnea, orthopnea, bilateral crackles, pitting edema: Congestive heart failure is the likely diagnosis.
- Untreated atrial fibrillation: A common complication is stroke.
- Rate control in atrial fibrillation: Metoprolol is commonly used.
- Acute coronary syndrome: Beta-blockers and aspirin are the first-line treatment.
- Sudden cardiac death: The most common cause is ventricular arrhythmias.
Hematology
- Iron deficiency anemia: Microcytic hypochromic cells are a characteristic finding in the peripheral blood smear.
- Inherited bleeding disorder: Von Willebrand disease is the most common.
- Microangiopathic hemolytic anemia: Hemolytic uremic syndrome is a common cause.
- Acute myeloid leukemia: Increased number of blasts in blood smear is typical.
- Polycythemia vera: Phlebotomy is the first-line treatment.
- Vitamin B12 deficiency: Elevated homocysteine and methylmalonic acid are common laboratory findings.
- Chronic myelogenous leukemia (CML): Philadelphia chromosome (BCR-ABL fusion gene) is a characteristic feature.
- Hospitalized patients with thrombocytopenia: Heparin-induced thrombocytopenia is common.
- Iron overload: Hemochromatosis is the most common cause.
Nephrology
- Chronic kidney disease (CKD) in adults: Diabetic nephropathy is the most common cause.
- Hypertensive nephrosclerosis: Elevated serum creatinine and proteinuria are common findings.
- Nephritic syndrome: Hematuria and hypertension are characteristics.
- Nephrotic syndrome: Proteinuria > 3.5 g/day, hypoalbuminemia and edema.
- Minimal change disease: A common cause of nephrotic syndrome in children.
- Acute kidney injury (AKI): Hyperkalemia is a common electrolyte disturbance.
- Chronic kidney disease (CKD) cause: Hypertensive nephrosclerosis is the most common cause of renal impairment with proteinuria and hematuria.
Pulmonary
- Chronic bronchitis: A common diagnosis in smokers, characterized by chronic cough and sputum production.
- Asthma: Decreased FEV1 is a hallmark feature.
- COPD: A common diagnosis in smokers, marked by persistent cough, dyspnea, and decreased breath sounds.
- Community-acquired pneumonia (CAP): Streptococcus pneumoniae is the most common cause in adults.
- Hospital-acquired pneumonia: Pseudomonas aeruginosa is the most common cause.
- Obstructive sleep apnea: Polysomnography is the primary test.
- Hypersensitivity pneumonitis: A common cause of cough, fatigue, and shortness of breath in patients with a history of exposure to bird droppings.
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Description
Review questions covering cardiology and hematology. Topics include heart failure, chest pain, atrial fibrillation, anemia, and bleeding disorders. Designed to test knowledge of common diagnoses, treatments, and complications in these medical specialties.