MS CH 21 Cardiovascular System Function Assessment and Therapeutic Measures
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Questions and Answers

What is the term for the point of maximum impulse of the heart?

  • Clubbing
  • Stenosis
  • Poikilothermy
  • Thrill (correct)

Which term refers to the abnormal sound heard on auscultation of a blood vessel?

  • Murmur
  • Bruit (correct)
  • Clot
  • Homans’ sign

What is the term for the inadequate blood supply to the tissues, often due to a narrowed or blocked artery?

  • Ischemic (correct)
  • Pericardial friction rub
  • Hypomagnesemia
  • Dysrhythmias

Which term refers to the swelling of the terminal phalanges of the fingers and toes, often associated with chronic hypoxia?

<p>Clubbing (D)</p> Signup and view all the answers

What is the term for the volume and pressure inside the heart at the end of diastole, before the next contraction?

<p>Preload (C)</p> Signup and view all the answers

Which term refers to the abnormal heart rhythm?

<p>Dysrhythmias (C)</p> Signup and view all the answers

Which structure anchors the tricuspid and mitral valves to the ventricle floor?

<p>Chordae tendineae (B)</p> Signup and view all the answers

What controls the heart's rhythm by generating the beat of the atria?

<p>Sinoatrial (SA) node (A)</p> Signup and view all the answers

Which valve separates the right atrium and the right ventricle?

<p>Tricuspid valve (C)</p> Signup and view all the answers

What is the usual ratio of systolic to diastolic to pulse pressure?

<p>3:2:1 (D)</p> Signup and view all the answers

What generates the beat of the ventricles at a slower rate than the atria?

<p>Atrioventricular (AV) node (A)</p> Signup and view all the answers

What hormone is released from the posterior pituitary to directly increase water reabsorption by the kidneys?

<p>Antidiuretic hormone (A)</p> Signup and view all the answers

What is responsible for providing oxygenated blood to the myocardium?

<p>Coronary circulation (A)</p> Signup and view all the answers

What initiates the renin-angiotensin-aldosterone mechanism, raising blood pressure?

<p>Renin (D)</p> Signup and view all the answers

Which part of the heart is responsible for generating approximately five times the force of the other part?

<p>Left ventricle (D)</p> Signup and view all the answers

Which hormones increase cardiac output and cause vasoconstriction in skin and viscera?

<p>Norepinephrine and epinephrine (D)</p> Signup and view all the answers

What happens if blood flow through the kidneys decreases?

<p>Renal filtration and urinary output decrease to preserve blood volume (D)</p> Signup and view all the answers

What is the effect of atrial natriuretic peptide on blood pressure?

<p>It decreases blood pressure (B)</p> Signup and view all the answers

What primarily regulates the diameter of arteries?

<p>Sympathetic division of the autonomic nervous system (B)</p> Signup and view all the answers

What is the function of precapillary sphincters?

<p>Regulate blood flow through a capillary network (C)</p> Signup and view all the answers

How is blood pressure measured?

<p>In millimeters of mercury (mm Hg), systolic over diastolic (B)</p> Signup and view all the answers

What is the normal average of systemic arterial pressure?

<p>120/80 mm Hg (A)</p> Signup and view all the answers

What primarily affects blood pressure?

<p>Heart rate, force, and the strength of the heart's contractions (A)</p> Signup and view all the answers

What is the function of capillaries in the cardiovascular system?

<p>Permit exchanges of gases, nutrients, and waste products between the blood and tissues (B)</p> Signup and view all the answers

What is the average resting cardiac output in liters per minute?

<p>5 to 6 L/min (A)</p> Signup and view all the answers

What is the average ejection fraction as a percentage of the total amount of blood within the left ventricle that is ejected with every heartbeat?

<p>55% to 70% (C)</p> Signup and view all the answers

What is the role of the sinoatrial (SA) node in the cardiac conduction pathway?

<p>Initiates each heartbeat (B)</p> Signup and view all the answers

What effect does stretching of the ventricular myocardium have during exercise?

<p>Increases stroke volume and heart rate (A)</p> Signup and view all the answers

Which hormone increases the heart rate and force of contraction?

<p>Epinephrine (A)</p> Signup and view all the answers

Which part of the medulla sends impulses through the parasympathetic nervous system to slow the heart rate?

<p>Inhibitory center (B)</p> Signup and view all the answers

What is the term for the inability of the heart to pump a sufficient amount of blood to meet the body's metabolic demands?

<p>Cardiogenic shock (D)</p> Signup and view all the answers

Which term refers to the inability of the heart to maintain adequate circulation of blood to meet the body's needs?

<p>Cardiogenic shock (B)</p> Signup and view all the answers

What is the formula to calculate cardiac output?

<p>Cardiac Output = Heart Rate × Stroke Volume (A)</p> Signup and view all the answers

What is the term for the phenomenon where the pulse becomes weaker during inspiration and stronger during expiration?

<p>Pulsus paradoxus (B)</p> Signup and view all the answers

What is the average resting cardiac output in liters per minute?

<p>5 to 6 L per minute (B)</p> Signup and view all the answers

Which term refers to the alternating strong and weak pulses, usually related to severe left ventricular failure?

<p>Pulsus alternans (C)</p> Signup and view all the answers

What is the average ejection fraction as a percentage of the total amount of blood within the left ventricle that is ejected with every heartbeat?

<p>55% to 70% (D)</p> Signup and view all the answers

What is the term for the condition characterized by a biphasic pulse, often associated with aortic regurgitation?

<p>Pulsus bisferiens (D)</p> Signup and view all the answers

What initiates each heartbeat in the cardiac conduction pathway?

<p>Sinoatrial (SA) node (C)</p> Signup and view all the answers

Which term refers to the decrease in systolic and diastolic blood pressure upon standing, often leading to dizziness or syncope?

<p>Orthostatic hypotension (A)</p> Signup and view all the answers

What happens to the heart rate and stroke volume during exercise?

<p>Increase (B)</p> Signup and view all the answers

Which hormone increases the heart rate and force of contraction?

<p>Epinephrine (A)</p> Signup and view all the answers

What is the typical ratio of systolic to diastolic to pulse pressure?

<p>3:2:1 (A)</p> Signup and view all the answers

What hormone directly increases water reabsorption by the kidneys, thus increasing blood volume and blood pressure?

<p>Antidiuretic hormone (B)</p> Signup and view all the answers

Which hormones increase cardiac output and cause vasoconstriction in skin and viscera?

<p>Norepinephrine and epinephrine (A)</p> Signup and view all the answers

What initiates the renin-angiotensin-aldosterone mechanism, raising blood pressure?

<p>Decreased blood pressure (B)</p> Signup and view all the answers

Which hormone is released from the posterior pituitary to directly increase water reabsorption by the kidneys?

<p>Antidiuretic hormone (D)</p> Signup and view all the answers

What is the effect of atrial natriuretic peptide on blood pressure?

<p>Decreases blood pressure (C)</p> Signup and view all the answers

What primarily regulates the diameter of arteries?

<p>Sympathetic division of the autonomic nervous system (C)</p> Signup and view all the answers

What is the term for the volume and pressure inside the heart at the end of diastole, before the next contraction?

<p>End-diastolic volume (C)</p> Signup and view all the answers

What happens if blood flow through the kidneys decreases?

<p>Decreased urine production (D)</p> Signup and view all the answers

What is the effect of atrial natriuretic peptide on blood pressure?

<p>Decreases blood pressure (A)</p> Signup and view all the answers

What is the usual ratio of systolic to diastolic to pulse pressure?

<p>3:1:2 (B)</p> Signup and view all the answers

What is the term for the swelling of the terminal phalanges of the fingers and toes, often associated with chronic hypoxia?

<p>Clubbing (B)</p> Signup and view all the answers

Which structure provides oxygenated blood to the myocardium and returns deoxygenated blood to the right atrium?

<p>Coronary sinus (C)</p> Signup and view all the answers

What anchors the tricuspid and mitral valves to the ventricle floor?

<p>Chordae tendineae (B)</p> Signup and view all the answers

What generates the beat of the ventricles at a slower rate than the atria?

<p>Atrioventricular (AV) node (B)</p> Signup and view all the answers

What causes the first of the two major heart sounds, 'lubb'?

<p>Closure of the AV valves during ventricular systole (D)</p> Signup and view all the answers

What is responsible for pumping blood through the aortic semilunar valve to the body?

<p>Left ventricle (A)</p> Signup and view all the answers

What controls the heart's rhythm by generating the beat of the atria?

<p>Sinoatrial (SA) node (A)</p> Signup and view all the answers

Which term refers to the abnormal sound heard on auscultation of a blood vessel?

<p>Bruit (C)</p> Signup and view all the answers

What is the term for the swelling of the terminal phalanges of the fingers and toes, often associated with chronic hypoxia?

<p>Clubbing (D)</p> Signup and view all the answers

What is the term for the alternating strong and weak pulses, usually related to severe left ventricular failure?

<p>Pulse deficit (D)</p> Signup and view all the answers

What is the term for the volume and pressure inside the heart at the end of diastole, before the next contraction?

<p>Preload (B)</p> Signup and view all the answers

What is the term for the point of maximum impulse of the heart?

<p>Point of maximum impulse (B)</p> Signup and view all the answers

What is the term for the abnormal heart rhythm?

<p>Dysrhythmias (D)</p> Signup and view all the answers

What is the typical ratio of systolic to diastolic to pulse pressure?

<p>3:2:1 (D)</p> Signup and view all the answers

What hormone directly increases water reabsorption by the kidneys, thus increasing blood volume and blood pressure?

<p>Antidiuretic hormone (D)</p> Signup and view all the answers

Which hormones increase cardiac output and cause vasoconstriction in skin and viscera?

<p>Norepinephrine and epinephrine (D)</p> Signup and view all the answers

What initiates the renin-angiotensin-aldosterone mechanism, raising blood pressure?

<p>Decreased blood pressure (C)</p> Signup and view all the answers

What effect does stretching of the ventricular myocardium have during exercise?

<p>Increases heart rate (B)</p> Signup and view all the answers

What is the function of atrial natriuretic peptide on blood pressure?

<p>Decreases blood pressure (B)</p> Signup and view all the answers

What primarily regulates the diameter of arteries?

<p>Sympathetic division of the autonomic nervous system (A)</p> Signup and view all the answers

What is the normal average of systemic arterial pressure?

<p>120/80 mm Hg (B)</p> Signup and view all the answers

What is the term for the point of maximum impulse of the heart?

<p>Point of maximal impulse (PMI) (A)</p> Signup and view all the answers

What is the term for the phenomenon where the pulse becomes weaker during inspiration and stronger during expiration?

<p>Pulsus paradoxus (A)</p> Signup and view all the answers

What is the term for the inadequate blood supply to the tissues, often due to a narrowed or blocked artery?

<p>Ischemia (B)</p> Signup and view all the answers

What is the effect of stretching of the ventricular myocardium during exercise?

<p>Increases stroke volume (D)</p> Signup and view all the answers

What is the term for the volume and pressure inside the heart at the end of diastole, before the next contraction?

<p>End-diastolic volume (A)</p> Signup and view all the answers

What anchors the tricuspid and mitral valves to the ventricle floor?

<p>Chordae tendineae (C)</p> Signup and view all the answers

What primarily regulates the diameter of arteries?

<p>Nitric oxide (C)</p> Signup and view all the answers

What is the term for the condition characterized by a biphasic pulse, often associated with aortic regurgitation?

<p>Pulsus alternans (C)</p> Signup and view all the answers

What is the average ejection fraction as a percentage of the total amount of blood within the left ventricle that is ejected with every heartbeat?

<p>60-65% (A)</p> Signup and view all the answers

What is the term for the swelling of the terminal phalanges of the fingers and toes, often associated with chronic hypoxia?

<p>Clubbing (A)</p> Signup and view all the answers

What is the formula to calculate cardiac output?

<p>Cardiac Output = Stroke Volume $\times$ Heart Rate (C)</p> Signup and view all the answers

What is the typical range for ejection fraction, a measure of ventricular efficiency?

<p>50% to 70% (D)</p> Signup and view all the answers

What is the role of the atrioventricular (AV) node in the cardiac conduction pathway?

<p>To slow the impulse to allow the atria time to contract and the ventricles to fill with blood (A)</p> Signup and view all the answers

What effect does epinephrine have on the heart?

<p>Increases the heart rate and force of contraction (A)</p> Signup and view all the answers

What happens to cardiac output during exercise?

<p>Increases (C)</p> Signup and view all the answers

What is the function of the precapillary sphincters in the cardiovascular system?

<p>Regulate blood flow into capillaries (C)</p> Signup and view all the answers

What is the term for the inability of the heart to pump a sufficient amount of blood to meet the body's metabolic demands?

<p>Dysrhythmias (D)</p> Signup and view all the answers

Which term refers to the abnormal sound heard on auscultation of a blood vessel?

<p>Murmur (B)</p> Signup and view all the answers

What is the term for the point of maximum impulse of the heart?

<p>Point of maximum impulse (D)</p> Signup and view all the answers

What is the term for the volume and pressure inside the heart at the end of diastole, before the next contraction?

<p>Preload (D)</p> Signup and view all the answers

Which term refers to the alternating strong and weak pulses, usually related to severe left ventricular failure?

<p>Pulse deficit (D)</p> Signup and view all the answers

What is the term for the condition characterized by a biphasic pulse, often associated with aortic regurgitation?

<p>Thrill (A)</p> Signup and view all the answers

What primarily regulates the diameter of arteries?

<p>Sympathetic division of the autonomic nervous system (A)</p> Signup and view all the answers

What is the normal average of systemic arterial pressure?

<p>120/80 mm Hg (D)</p> Signup and view all the answers

What primarily affects blood pressure?

<p>Heart rate and force of heart's contractions (A)</p> Signup and view all the answers

What is the force of the blood against the walls of the blood vessels measured in?

<p>Millimeters of mercury (mm Hg) (B)</p> Signup and view all the answers

What regulates the blood flow through a capillary network?

<p>Precapillary sphincters (B)</p> Signup and view all the answers

What primarily carries blood from capillaries to the heart?

<p>Venules (C)</p> Signup and view all the answers

What is the formula to calculate cardiac output?

<p>$ ext{Cardiac output} = ext{Heart rate} imes ext{Stroke volume}$ (B)</p> Signup and view all the answers

What primarily regulates the diameter of arteries?

<p>Sympathetic and parasympathetic nervous systems (D)</p> Signup and view all the answers

What is the typical range for ejection fraction, a measure of ventricular efficiency?

<p>50% to 70% (D)</p> Signup and view all the answers

What primarily controls the heart's rhythm by generating the beat of the atria?

<p>Sinoatrial (SA) node (A)</p> Signup and view all the answers

What effect does epinephrine have on the heart?

<p>Increases the heart rate and force of contraction (D)</p> Signup and view all the answers

What happens to cardiac output during exercise?

<p>Increases (B)</p> Signup and view all the answers

What is the term for the simultaneous contraction and relaxation of the atria and ventricles, creating the normal heart sounds?

<p>Systole (C)</p> Signup and view all the answers

What anchors the tricuspid and mitral valves to the ventricle floor?

<p>Chordae tendineae (A)</p> Signup and view all the answers

What generates the beat of the ventricles at a slower rate than the atria?

<p>Atrioventricular (AV) node (B)</p> Signup and view all the answers

What primarily affects the difference in systemic and pulmonary blood pressure?

<p>Thicker walls of the left ventricle (C)</p> Signup and view all the answers

What is the term for the inability of the heart to maintain adequate circulation of blood to meet the body's needs?

<p>Heart failure (D)</p> Signup and view all the answers

What is the term for the alternating strong and weak pulses, usually related to severe left ventricular failure?

<p>Pulsus alternans (C)</p> Signup and view all the answers

What is the typical ratio of systolic to diastolic to pulse pressure?

<p>3:2:1 (D)</p> Signup and view all the answers

Which hormone directly increases water reabsorption by the kidneys, thus increasing blood volume and blood pressure?

<p>Aldosterone (A)</p> Signup and view all the answers

What hormone, released from the posterior pituitary, directly increases water reabsorption by the kidneys, thus increasing blood volume and blood pressure?

<p>Antidiuretic hormone (D)</p> Signup and view all the answers

Which hormones increase cardiac output and cause vasoconstriction in skin and viscera?

<p>Norepinephrine and Epinephrine (B)</p> Signup and view all the answers

What primarily affects blood pressure?

<p>Renin (B)</p> Signup and view all the answers

What hormone is involved in directly increasing water reabsorption by the kidneys, thus increasing blood volume and blood pressure?

<p>Antidiuretic hormone (C)</p> Signup and view all the answers

True or false: The usual ratio of systolic to diastolic to pulse pressure is 3:2:1.

<p>True (A)</p> Signup and view all the answers

True or false: Decreased blood pressure stimulates the kidneys to secrete renin, which initiates the renin-angiotensin-aldosterone mechanism, raising blood pressure.

<p>True (A)</p> Signup and view all the answers

True or false: Norepinephrine and epinephrine increase cardiac output and cause vasoconstriction in skin and viscera.

<p>True (A)</p> Signup and view all the answers

True or false: Antidiuretic hormone, released from the posterior pituitary, directly increases water reabsorption by the kidneys, thus increasing blood volume and blood pressure.

<p>True (A)</p> Signup and view all the answers

True or false: Atrial natriuretic peptide has no effect on blood pressure.

<p>False (B)</p> Signup and view all the answers

True or false: The kidneys are not of great importance in the regulation of blood pressure.

<p>False (B)</p> Signup and view all the answers

True or false: Atrial natriuretic peptide decreases blood pressure.

<p>True (A)</p> Signup and view all the answers

True or false: Renin is not secreted when blood flow through the kidneys decreases.

<p>False (B)</p> Signup and view all the answers

True or false: Other hormones that affect blood pressure include those of the adrenal medulla, norepinephrine and epinephrine, which decrease cardiac output and cause vasodilation in skin and viscera.

<p>False (B)</p> Signup and view all the answers

True or false: Decreased blood pressure inhibits the renin-angiotensin-aldosterone mechanism.

<p>False (B)</p> Signup and view all the answers

Flashcards

What is Stroke Volume?

The amount of blood ejected by a ventricle in one contraction. It averages 60-80 mL per beat.

What is Ejection Fraction?

A measure of ventricular efficiency. It is normally 55% to 70% of the total amount of blood within the left ventricle that is ejected with every heartbeat.

What is Cardiac Output?

The product of stroke volume and heart rate, with an average resting value of 5-6 L per minute.

What is the Sinoatrial Node?

An autorhythmic structure in the right atrium that initiates each heartbeat by depolarizing about 100 times per minute.

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What is Normal Sinus Rhythm?

The normal rhythm of the heart, initiated by the sinoatrial node.

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What is the Atrioventricular Node?

A structure in the heart that slows the conduction of impulses from the SA node, allowing the atria to contract completely and the ventricles to fill with blood.

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What is the Heart's Skeleton?

A fibrous structure that insulates the ventricles, preventing direct conduction of impulses to them, ensuring only impulses passing through the AV node can reach the ventricles.

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How does exercise affect cardiac output?

The increase in stroke volume and heart rate during exercise, due to the stretching of the ventricular myocardium by increased venous return.

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What is the role of the nervous system in heart regulation?

The part of the nervous system that can alter heart rate in response to environmental circumstances.

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How does Epinephrine affect the heart?

A hormone that increases the heart rate and force of contraction.

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How does Atrial Natriuretic Peptide affect the heart?

A hormone that increases the excretion of sodium by the kidneys, reducing blood volume and pressure.

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What are arteries and arterioles?

Blood vessels that carry blood from the heart to capillaries, with walls comprising three layers.

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What is the Cardiac Center?

A center in the medulla oblongata that controls the acceleration and inhibition of heart rate.

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What is the Cardiovascular System?

The system composed of the heart, blood, and vessels, responsible for distributing blood throughout the body.

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What is the Pericardium?

The protective sac that encloses the heart, comprising the fibrous pericardium, parietal pericardium, and visceral pericardium.

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What is Myocardium?

The muscular tissue that forms the walls of the heart's chambers.

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What is Endocardium?

The inner lining of the heart chambers, also covering the valves and extending into blood vessels.

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What is Coronary Circulation?

The circulation of blood through the heart muscle itself. Oxygenated blood is supplied to the myocardium and deoxygenated blood returns to the right atrium via the coronary sinus.

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What is the Tricuspid Valve?

A valve that controls the flow of blood from the right atrium to the right ventricle.

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What is the Pulmonary Semilunar Valve?

A valve that controls the flow of blood from the right ventricle to the pulmonary artery.

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What is the Mitral Valve?

A valve that controls the flow of blood from the left atrium to the left ventricle.

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What is the Aortic Semilunar Valve?

A valve that controls the flow of blood from the left ventricle to the aorta.

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What is the Left Ventricle?

The powerful pump that propels blood to the body through the aorta.

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What are Chordae Tendineae?

The cords that anchor the cusps of the tricuspid and mitral valves to the ventricle floor.

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What are Papillary Muscles?

The muscles that attach to the chordae tendineae and help control the opening and closing of the tricuspid and mitral valves.

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What is the Cardiac Cycle?

The simultaneous contraction and relaxation of the atria and ventricles that create the normal heart sounds.

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What is the 'Lubb' sound in the heart?

The first heart sound, caused by the closure of the AV valves during ventricular systole.

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What is the importance of the Cardiovascular System?

The system that plays a crucial role in distributing blood and oxygen throughout the body, with the heart as its central organ.

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Study Notes

Cardiac Output and Conduction Pathway

  • Cardiac output is determined by multiplying stroke volume by heart rate, with an average resting cardiac output of 5 to 6 L per minute.
  • Stroke volume, the amount of blood ejected by a ventricle in one contraction, averages 60 to 80 mL/beat.
  • Ejection fraction, a measure of ventricular efficiency, is normally 55% to 70% of the total amount of blood within the left ventricle that is ejected with every heartbeat.
  • The cardiac conduction pathway involves the sinoatrial (SA) node, which is autorhythmic and depolarizes about 100 times per minute, initiating each heartbeat.
  • The SA node is called the pacemaker, and a normal heartbeat is called a normal sinus rhythm.
  • Impulses travel from the SA node to the atrioventricular (AV) node, where the impulse slows considerably to allow the atria time to contract completely and the ventricles to fill with blood.
  • The heart’s skeleton insulates the ventricles, ensuring that only impulses passing through the AV node can enter.
  • During exercise, venous return increases, stretching the ventricular myocardium, causing an increase in stroke volume and heart rate, leading to an increase in cardiac output.
  • The nervous system can change the heart rate in response to environmental circumstances, with the medulla oblongata receiving sensory input and altering heart function.
  • Epinephrine increases the heart rate and force of contraction, while atrial natriuretic peptide increases the excretion of sodium by the kidneys, reducing blood volume and pressure.
  • Arteries and arterioles carry blood from the heart to capillaries, with their walls consisting of three layers.
  • The cardiac center in the medulla contains an acceleratory center and an inhibitory center, which send impulses through the sympathetic and parasympathetic nervous systems to accelerate or slow the heart rate, respectively.

Anatomy and Physiology of the Cardiovascular System

  • The cardiovascular system comprises the heart, blood, and vessels, responsible for distributing blood throughout the body.
  • The heart is located within the thoracic cavity and is enclosed by the fibrous pericardium, parietal pericardium, and visceral pericardium.
  • The walls of the heart's chambers are made of myocardium and lined with endocardium, which also covers the valves and continues into the blood vessels.
  • Coronary circulation provides oxygenated blood to the myocardium and returns deoxygenated blood to the right atrium through the coronary sinus.
  • Blood flows from the right atrium through the tricuspid valve into the right ventricle, then through the pulmonary semilunar valve to the lungs, and from the left atrium through the mitral valve into the left ventricle.
  • The left ventricle pumps blood through the aortic semilunar valve to the body via the aorta, generating approximately five times the force of the right ventricle.
  • The tricuspid and mitral valves consist of three and two cusps, respectively, anchored to the ventricle floor by chordae tendineae and papillary muscles.
  • Each ventricle pumps the same amount of blood, but the left ventricle has much thicker walls and pumps with greater force, leading to the difference in systemic and pulmonary blood pressure.
  • The heart's rhythm is controlled by the sinoatrial (SA) node, which generates the beat of the atria, and the atrioventricular (AV) node, which generates the beat of the ventricles at a slower rate.
  • The cardiac cycle involves the simultaneous contraction and relaxation of the atria and ventricles, creating the normal heart sounds.
  • The first of the two major sounds, "lubb," is caused by the closure of the AV valves during ventricular systole.
  • The cardiovascular system plays a crucial role in the distribution of blood and oxygen throughout the body, with the heart as the central organ responsible for pumping blood.

Cardiac Output and Conduction Pathway

  • Cardiac output is determined by multiplying stroke volume by heart rate, with an average resting cardiac output of 5 to 6 L per minute.
  • Stroke volume, the amount of blood ejected by a ventricle in one contraction, averages 60 to 80 mL/beat.
  • Ejection fraction, a measure of ventricular efficiency, is normally 55% to 70% of the total amount of blood within the left ventricle that is ejected with every heartbeat.
  • The cardiac conduction pathway involves the sinoatrial (SA) node, which is autorhythmic and depolarizes about 100 times per minute, initiating each heartbeat.
  • The SA node is called the pacemaker, and a normal heartbeat is called a normal sinus rhythm.
  • Impulses travel from the SA node to the atrioventricular (AV) node, where the impulse slows considerably to allow the atria time to contract completely and the ventricles to fill with blood.
  • The heart’s skeleton insulates the ventricles, ensuring that only impulses passing through the AV node can enter.
  • During exercise, venous return increases, stretching the ventricular myocardium, causing an increase in stroke volume and heart rate, leading to an increase in cardiac output.
  • The nervous system can change the heart rate in response to environmental circumstances, with the medulla oblongata receiving sensory input and altering heart function.
  • Epinephrine increases the heart rate and force of contraction, while atrial natriuretic peptide increases the excretion of sodium by the kidneys, reducing blood volume and pressure.
  • Arteries and arterioles carry blood from the heart to capillaries, with their walls consisting of three layers.
  • The cardiac center in the medulla contains an acceleratory center and an inhibitory center, which send impulses through the sympathetic and parasympathetic nervous systems to accelerate or slow the heart rate, respectively.

Anatomy and Physiology of the Cardiovascular System

  • The cardiovascular system comprises the heart, blood, and vessels, responsible for distributing blood throughout the body.
  • The heart is located within the thoracic cavity and is enclosed by the fibrous pericardium, parietal pericardium, and visceral pericardium.
  • The walls of the heart's chambers are made of myocardium and lined with endocardium, which also covers the valves and continues into the blood vessels.
  • Coronary circulation provides oxygenated blood to the myocardium and returns deoxygenated blood to the right atrium through the coronary sinus.
  • Blood flows from the right atrium through the tricuspid valve into the right ventricle, then through the pulmonary semilunar valve to the lungs, and from the left atrium through the mitral valve into the left ventricle.
  • The left ventricle pumps blood through the aortic semilunar valve to the body via the aorta, generating approximately five times the force of the right ventricle.
  • The tricuspid and mitral valves consist of three and two cusps, respectively, anchored to the ventricle floor by chordae tendineae and papillary muscles.
  • Each ventricle pumps the same amount of blood, but the left ventricle has much thicker walls and pumps with greater force, leading to the difference in systemic and pulmonary blood pressure.
  • The heart's rhythm is controlled by the sinoatrial (SA) node, which generates the beat of the atria, and the atrioventricular (AV) node, which generates the beat of the ventricles at a slower rate.
  • The cardiac cycle involves the simultaneous contraction and relaxation of the atria and ventricles, creating the normal heart sounds.
  • The first of the two major sounds, "lubb," is caused by the closure of the AV valves during ventricular systole.
  • The cardiovascular system plays a crucial role in the distribution of blood and oxygen throughout the body, with the heart as the central organ responsible for pumping blood.

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Test your knowledge of cardiac output and the cardiac conduction pathway with this quiz. Explore topics such as stroke volume, ejection fraction, the SA node, AV node, and factors influencing heart rate and cardiac output.

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