Cardiac Muscle & Blood MCQs
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Questions and Answers

What is the correct sequence of events following the depolarization of transverse tubules in excitation-contraction coupling in cardiac muscle?

  • Calcium ion influx through sarcolemma, Calcium release into cytosol, actin and myosin attach, thin myofilaments slide toward the middle of sarcomeres (correct)
  • Calcium release into cytosol, actin and myosin attach, thin myofilaments slide toward the middle of sarcomeres, Calcium ion influx through sarcolemma
  • Actin and myosin attach, Calcium release into cytosol, Calcium ion influx through sarcolemma, thin myofilaments slide toward the middle of sarcomeres
  • thin myofilaments slide toward the middle of sarcomeres, Calcium release into cytosol, Calcium ion influx through sarcolemma, actin and myosin attach

The prolonged electrical depolarization of cardiac muscle cells that occurs during contraction is due primarily to the persistent influx of what ion?

Calcium

Which of the following are functions of blood plasma?

  • Having plasma proteins that exert an osmotic pressure favoring fluid absorption into the capillaries
  • Being in osmotic balance with red blood cells
  • Providing clotting factors that are ready to be activated
  • Transport of hormones
  • All of the above (correct)

Which of the following statements describe Erythrocytes?

<p>All of the above (E)</p> Signup and view all the answers

Based on the equation F = ΔP/R, the rate of fluid flow in a tube will increase if the pressure at the beginning is increased while the pressure at the end of the tube stays the same.

<p>True (A)</p> Signup and view all the answers

What change would most increase the resistance to blood flow in a blood vessel?

<p>Halving the diameter of the vessel (A)</p> Signup and view all the answers

The pacemaker of the heart is normally what structure?

<p>Sinoatrial node (SA node)</p> Signup and view all the answers

After sodium influx through Voltage-Gated channels occurs in ventricular cells, prolonged influx of calcium from the extracellular fluid occurs. No such calcium influx occurs in skeletal muscle cells.

<p>True (A)</p> Signup and view all the answers

The QRS complex in an electrocardiogram best represents what?

<p>Depolarization of the ventricles</p> Signup and view all the answers

The absolute refractory period of cardiac muscle cells is much longer than the refractory period of skeletal muscle cells

<p>True (A)</p> Signup and view all the answers

Closure of the atrioventricular valves occurs at the onset of the ventricular systole.

<p>True (A)</p> Signup and view all the answers

What occurs during isovolumetric ventricular contraction?

<p>No blood enters or leaves the ventricles</p> Signup and view all the answers

What best defines the cardiac output?

<p>The product of the heart rate and the volume ejected from the ventricle during a cardiac cycle</p> Signup and view all the answers

The frequency of action potentials generated by the SA node is increased by epinephrine.

<p>True (A)</p> Signup and view all the answers

According to the Frank-Starling mechanism of the heart, stroke volume increases with increased venous return

<p>True (A)</p> Signup and view all the answers

What determines the movement of blood in systemic veins?

<p>All of the above (E)</p> Signup and view all the answers

Which factor would NOT tend to increase systemic arterial blood pressure?

<p>Increased parasympathetic stimulation of the heart (C)</p> Signup and view all the answers

What is Atherosclerosis?

<p>The major cause of heart attacks</p> Signup and view all the answers

Flashcards

Cardiac Excitation-Contraction Sequence

Calcium influx, calcium release into cytosol, actin-myosin binding, myofilament sliding.

Ion for Prolonged Cardiac Depolarization

Calcium ions.

Key Blood Plasma Functions

Osmotic pressure, osmotic balance, clotting factors, hormone transport.

Erythrocyte Characteristics

Red, high surface area, no nucleus, carries O2 and CO2.

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Fluid Flow Equation (F = ΔP/R)

Flow increases if pressure at the start increases.

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Greatest Increase in Blood Flow Resistance

Halving the vessel diameter.

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Heart's Pacemaker

Sinoatrial node (SA node).

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Action Potential Differences

Ventricular cells have prolonged calcium influx; skeletal muscle cells do not.

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QRS Complex Represents

Depolarization of the ventricles.

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Cardiac Muscle Absolute Refractory Period

It is much longer than in skeletal muscle cells.

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Cardiac Cycle Key Event

Closure of the atrioventricular valves at ventricular systole onset.

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Isovolumetric Ventricular Contraction

No blood enters or leaves the ventricles.

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Cardiac Output Definition

Heart rate multiplied by stroke volume.

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SA Node Action Potential Frequency

Increased by epinephrine.

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Frank-Starling Mechanism

Stroke volume increases with increased venous return.

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Systemic Vein Blood Movement

Valves, pressure changes with breathing, pressure gradient, muscle contraction.

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NOT Increasing Systemic Arterial Pressure

Increased parasympathetic stimulation of the heart.

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Atherosclerosis

The major cause of heart attacks.

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Study Notes

  • Study notes for exam 3 practice questions

Excitation-Contraction Coupling in Cardiac Muscle

  • The correct sequence of events following the depolarization of transverse tubules involves:
    • Calcium ion influx through the sarcolemma.
    • Calcium release into the cytosol.
    • Attachment of actin and myosin.
    • Sliding of thin myofilaments toward the middle of sarcomeres.

Electrical Depolarization of Cardiac Muscle Cells

  • Prolonged electrical depolarization during contraction is primarily due to a persistent influx of calcium ions.

Functions of Blood Plasma

  • Key functions include:
    • Maintaining osmotic pressure to favor fluid absorption into capillaries via plasma proteins.
    • Maintaining osmotic balance with red blood cells.
    • Providing readily available clotting factors.
    • Hormones transport.

Description of Erythrocytes

  • Erythrocytes (red blood cells):
    • Are red in color.
    • Have a high surface-to-volume ratio.
    • Lack a nucleus when mature.
    • Transport oxygen and carbon dioxide in the blood.

Fluid Flow Dynamics

  • According to the equation F = ΔP/R, the rate of fluid flow in a tube increases if the pressure at the beginning increases while the pressure at the end stays constant.

Resistance to Blood Flow

  • Reducing the diameter of a blood vessel by half would most increase resistance to blood flow.

Pacemaker of the Heart

  • The sinoatrial node (SA node) is normally the heart's pacemaker.

Action Potentials in Cardiac vs. Skeletal Muscle

  • A key difference is that ventricular cardiac muscle cells experience a prolonged influx of calcium from extracellular fluid after sodium influx, which does not occur in skeletal muscle cells.

QRS Complex in Electrocardiogram

  • The QRS complex represents depolarization of the ventricles.

Refractory Period of Cardiac Muscle Cells

  • The absolute refractory period is much longer in cardiac muscle cells than in skeletal muscle cells.

The Cardiac Cycle

  • Closure of the atrioventricular valves marks the beginning of ventricular systole.

Isovolumetric Ventricular Contraction

  • During this phase, there is no blood entering or leaving the ventricles.

Cardiac Output

  • Cardiac output is defined as the product of heart rate and the volume ejected from the ventricle per cardiac cycle.

SA Node Action Potential Frequency

  • Epinephrine increases the frequency of action potentials generated by the SA node.

Frank-Starling Mechanism

  • According to this mechanism, stroke volume increases with increased venous return.

Movement of Blood in Systemic Veins

  • Several factors determine this movement:
    • Valves in the veins.
    • Diaphragm movement, causing decreased thoracic and increased abdominal pressure.
    • Blood pressure difference between systemic capillaries and the right atrium.
    • Contraction and relaxation of skeletal muscles.

Factors Affecting Systemic Arterial Blood Pressure

  • Increased parasympathetic stimulation of the heart does NOT increase systemic arterial blood pressure.

Atherosclerosis

  • Atherosclerosis is the major cause of heart attacks.

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Description

Study notes covering excitation-contraction coupling in cardiac muscle, electrical depolarization, functions of blood plasma, and erythrocyte characteristics. Key topics include calcium ion dynamics, osmotic pressure maintenance, and red blood cell properties. These notes are designed for exam 3 preparation.

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