Cardiac Development Quiz

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Questions and Answers

What structure forms from the union of the cardinal, vitelline, and umbilical veins?

  • Aortic sac
  • Bulbus cordis
  • Truncus arteriosus
  • Sinus venosus (correct)

The apical portion of the right ventricle is formed from which of the following?

  • Bulbus cordis (correct)
  • Primitive ventricle
  • Truncus arteriosus
  • Conus cordis

Which of the following is NOT derived from the sinus venosus?

  • Superior vena cava (SVC)
  • Posterior portion of the right atrium
  • Pulmonary veins
  • Aorta (correct)

During which week of development do the heart tubes fuse into a single endocardial heart tube?

<p>Week 3 (B)</p> Signup and view all the answers

What does the left 4th aortic arch form?

<p>Media portion of the aortic arch (C)</p> Signup and view all the answers

Which structure directly connects the primitive atrium with the left ventricle during early cardiac development?

<p>The atrioventricular canal (D)</p> Signup and view all the answers

What is the primary role of the septum secundum in atrial development?

<p>To form the foramen ovale (A)</p> Signup and view all the answers

The cessation of growth of the trabecular interventricular septum occurs when?

<p>When the ventricles stop expanding (B)</p> Signup and view all the answers

What is the significance of the atrioventricular canal shift during cardiac development?

<p>It establishes communication between the right atrium and the right ventricle. (B)</p> Signup and view all the answers

Which of the following is a temporary opening between the ventricles during cardiac development?

<p>Secondary interventricular foramen (C)</p> Signup and view all the answers

What is the correct sequence of initial heart development steps?

<p>Fusion of heart tubes, muscular contractions, S-shaped looping, septum primum formation (D)</p> Signup and view all the answers

What structure develops directly from the atrioventricular canal after the formation of endocardial cushions?

<p>Mitral and tricuspid valves (C)</p> Signup and view all the answers

What is the primary precursor for the aorta and pulmonary artery during heart development?

<p>Truncus arteriosus (C)</p> Signup and view all the answers

Which of the following describes the role of septum primum?

<p>Separates the right and left atria (A)</p> Signup and view all the answers

During week 4 of heart development, what connects the sinus venosus to the primitive atrium?

<p>Sinoatrial orifice (C)</p> Signup and view all the answers

Which structure appears as a small ridge on the primitive ventricle?

<p>Ventricular septum (A)</p> Signup and view all the answers

What best describes the developmental progression of the ventricles during week 4?

<p>The ventricles expand as the ventricular septum forms then separate fully (A)</p> Signup and view all the answers

In the developing heart, where are the endocardial cushions located?

<p>In the atrioventricular canal (C)</p> Signup and view all the answers

What is the primary role of the septum primum during week 5 of cardiac development?

<p>To close the ostium primum initially. (B)</p> Signup and view all the answers

What happens to the sinoatrial orifice during week 5 of heart development?

<p>It shifts to the right atrium. (D)</p> Signup and view all the answers

Where does the ostium secundum form during week 5 of cardiac development?

<p>In the superior portion of the septum primum. (C)</p> Signup and view all the answers

Which structure contributes to the formation of both the right and left ventricular outflow tracts?

<p>Trabecular expansion from the bulbus cordis. (D)</p> Signup and view all the answers

What structure is located at the base of the sinoatrial orifice?

<p>Coronary sinus orifice. (B)</p> Signup and view all the answers

What is the external demarcation between the developing right and left ventricles during week 5?

<p>Interventricular sulcus. (B)</p> Signup and view all the answers

Which of these structures does NOT directly contribute to the formation of the right ventricle?

<p>Trabecular expansion from the primitive ventricle. (C)</p> Signup and view all the answers

What is the fate of the left venous valve and septum spurium during week 5?

<p>They fuse with the septum secundum. (C)</p> Signup and view all the answers

What structure acts as a flap controlling blood flow between the atria during fetal development?

<p>Septum primum (C)</p> Signup and view all the answers

What physiological change causes the foramen ovale to close at birth?

<p>Increase in left atrial pressure (C)</p> Signup and view all the answers

The membranous septum plays a critical role in which process?

<p>Separation of the ventricles (A)</p> Signup and view all the answers

What is the origin of the cusps of the aortic and pulmonic valves?

<p>Bulbar ridges of the truncus arteriosus (C)</p> Signup and view all the answers

By the end of the 7th week of development, what major milestone is achieved in heart development?

<p>Main heart development is complete, and fetal circulation is in place. (A)</p> Signup and view all the answers

In fetal circulation, which vessel carries the most oxygen-rich blood?

<p>Umbilical vein (B)</p> Signup and view all the answers

What is the primary reason that blood bypasses the fetal lungs?

<p>High pulmonary vascular resistance (D)</p> Signup and view all the answers

Which shunt moves blood from the right atrium to the left atrium in the fetus?

<p>Foramen ovale (D)</p> Signup and view all the answers

What is the role of the placenta in fetal circulation?

<p>To exchange oxygen, carbon dioxide, nutrients, and waste between the mother and the fetus (C)</p> Signup and view all the answers

In fetal circulation, which vessel does the ductus arteriosus directly connect to?

<p>Aorta (D)</p> Signup and view all the answers

In a fetus, what is the typical pressure relationship between the right (R) and left (L) sides of the heart?

<p>R &gt; L (B)</p> Signup and view all the answers

What is the primary function of the ductus venosus in the fetus?

<p>To bypass the liver (B)</p> Signup and view all the answers

What is the approximate oxygen saturation on the right side of the heart at birth?

<p>75% (C)</p> Signup and view all the answers

When does the ductus arteriosus typically close in a newborn?

<p>Almost immediately after birth, due to muscular contractions. (B)</p> Signup and view all the answers

What is the primary function of the Eustachian valve in fetal circulation?

<p>To direct blood towards the foramen ovale, (A)</p> Signup and view all the answers

What is the remnant of the ductus venosus in an adult?

<p>Ligamentum venosum (D)</p> Signup and view all the answers

Which pathway does the majority of blood take as it exits the right ventricle in fetal circulation?

<p>Ductus arteriosus to the aorta. (C)</p> Signup and view all the answers

What causes the closure of the umbilical arteries shortly after birth?

<p>Muscular contractions due to rising O2 levels. (D)</p> Signup and view all the answers

What is the effect of the newborns first breath on fetal circulation?

<p>A decrease in vascular resistance in the lungs. (D)</p> Signup and view all the answers

What is the immediate cause of the interruption of blood flow through the placenta at birth?

<p>The cutting of the umbilical cord. (B)</p> Signup and view all the answers

In fetal circulation, where does depleted blood from the upper body enter the heart?

<p>Superior vena cava (SVC) (A)</p> Signup and view all the answers

Flashcards

Early Heart Development

The heart starts as two separate tubes, one on each side of the midline, in the head region of the embryo.

Heart Tube Fusion

During week 3, the two heart tubes fuse together to form a single continuous tube. This tube then develops specific regions.

Sinus Venosus

The caudal end of the fused heart tube, formed by the union of veins, matures into crucial structures like the superior and inferior vena cava.

Bulbus Cordis

The bulbus cordis, a region of the heart tube, develops into the apical portion of the right ventricle and the outflow tracts for both ventricles.

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Truncus Arteriosus

The truncus arteriosus, a vital part of the heart tube, gives rise to the major arteries supplying blood to the body and lungs.

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Trabecular Interventricular Septum

A muscular wall that forms between the two ventricles during the sixth week of fetal development.

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Foramen Ovale

A temporary opening between the right and left atria that allows blood to bypass the fetal lungs.

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Aortic Annulus

The point where the aorta attaches to the heart.

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Endocardial Cushions

Two cushions of tissue that fuse to form the atrioventricular valves and help divide the heart into chambers.

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Shifting Atrioventricular Canal

During development, the atrioventricular canal shifts to the right, connecting the left atrium to the left ventricle and the right atrium to the right ventricle.

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Fusion of Heart Tubes

Two separate heart tubes formed during earlier stages of development fuse together to create a single, continuous heart tube.

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Heart Contractions and Beating

The heart begins to beat due to muscle contractions. This marks the start of the heart's pumping action.

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S-Shaped Loop Formation

As the heart grows, it folds upon itself, taking on an S-shaped form.

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Septum Primum Formation

A thin wall begins to form within the primitive atrium, dividing it into two chambers.

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Sinus Venosus and Primitive Atrium Communication

A connection exists between the sinus venosus - a structure responsible for receiving blood from the body - and the primitive atrium, allowing blood flow between the two.

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Development of MV and TV

As the atrioventricular canal is divided by endocardial cushions, the mitral valve - controlling blood flow from left atrium to left ventricle - and tricuspid valve - controlling blood flow from right atrium to right ventricle - are formed.

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Ventricular Septum

A small ridge appears on the primitive ventricle, which will eventually become the ventricular septum, dividing the ventricle into left and right chambers.

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Foramen Ovale Closure

The closure of the foramen ovale, a hole between the atria, occurs at birth when the first breath is taken. This happens because left atrial pressure increases, forcing the septum primum against the septum secundum, closing the opening.

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Ventricular Separation

The membranous septum completes the separation of the ventricles by closing the secondary interventricular foramen, ensuring that oxygenated and deoxygenated blood flow is completely separated.

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Truncus Arteriosus Division

The truncus arteriosus, a vital blood vessel, splits into two important arteries: the aorta and the pulmonary artery. This division is a crucial step in the development of the heart's blood supply system.

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Truncus Arteriosus Spiraling

The truncus arteriosus spirals during development, creating a twisted arrangement that ensures the correct connection of the aorta and pulmonary artery to the ventricles.

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Aorta and Pulmonary Artery Formation

The truncus arteriosus, once a single structure, divides into the aorta and the pulmonary artery, creating distinct pathways for oxygenated and deoxygenated blood.

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Septum Primum

A thin membrane in the developing heart that helps divide the atria. It closes the opening called ostium primum.

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Ostium Secundum

A secondary opening that forms above the septum primum, allowing blood to flow between the atria.

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Septum Secundum (Internal)

Develops to the right side of the septum primum and helps complete the division of the atria.

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Sinoatrial Orifice

The area where the sinoatrial node is located and shifts to the right side during development, connecting only to the right atrium.

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Coronary Sinus Orifice

This orifice is how blood enters the heart and forms at the base of the sinoatrial orifice.

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Bulboventricular Development

The lower chamber of the heart, where the ventricles grow inferiorly from the bulbus cordis.

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Trabecular Expansion

Small pockets in the heart wall that extend from the bulbus cordis and primitive ventricle, contributing to the ventricles.

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Primitive Ventricle

The region where the heart starts its development and is part of the right ventricle.

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Fetal Circulation

The circulatory system of a fetus, where blood flow bypasses the lungs due to their fluid-filled state.

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Ductus Arteriosus

A blood vessel connecting the pulmonary artery to the aorta in a fetus, allowing blood to bypass the lungs.

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Placenta

The organ responsible for providing oxygen and nutrients to the fetus and removing waste products.

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Umbilical Vein

The only vessel carrying oxygen-rich blood in the fetus, transporting blood from the placenta to the fetal heart.

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Blood Mixing in Fetus

Blood flow in the fetus primarily mixes oxygen-rich and oxygen-depleted blood due to the bypassing of the lungs.

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Fetal Heart Pressure

The pressure inside the fetal heart, where the right side has higher pressure than the left side.

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Purpose of Fetal Circulation

The primary function of the fetal circulatory system, ensuring adequate oxygenation and nutrient delivery to the developing fetus despite the lungs being non-functional.

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What is the ductus arteriosus?

The ductus arteriosus is a blood vessel that connects the pulmonary artery to the aorta in the fetus, allowing blood to bypass the lungs.

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What is the foramen ovale?

The foramen ovale is a temporary opening between the right and left atria of the heart in the fetus, allowing blood to bypass the fetal lungs.

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What is the ductus venosus?

The ductus venosus is a blood vessel that connects the umbilical vein to the inferior vena cava in the fetus, allowing blood to bypass the liver.

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What blood vessels are found in the umbilical cord?

The umbilical cord contains three blood vessels: two umbilical arteries and one umbilical vein.

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What is the placenta?

The placenta is the organ responsible for providing oxygen and nutrients to the fetus and removing waste.

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How does the first breath of a newborn affect circulation?

The first breath of a newborn causes the lungs to expand and fill with air, increasing pulmonary blood flow and closing the foramen ovale.

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What happens to the ductus arteriosus after birth?

The closure of the ductus arteriosus is almost immediate after birth due to muscular contractions triggered by higher oxygen levels.

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What happens to the umbilical arteries and vein after birth?

The umbilical arteries and vein close shortly after birth due to contractions of smooth muscles, triggered by rising oxygen levels.

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