Cardiac Cellular Homeostasis and Myocyte Renewal Quiz
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Questions and Answers

What is the main focus of the study by Bergmann et al. 2009?

  • Cardiomyocyte renewal in the human heart (correct)
  • The post-mitotic nature of the adult heart
  • The role of stem cells in the heart
  • The effect of exercise on cardiac growth

Which of the following parameters was NOT used to categorize rats in the study by Waring et al. 2014?

  • Type of exercise
  • Age (correct)
  • Level of intensity
  • Control group

What is the main cellular component responsible for contraction in the heart?

  • Stem Cells
  • Cardiomyocytes (correct)
  • Extracellular Matrix
  • Vasculature

What type of growth was induced by high-intensity exercise training in rats?

<p>Concentric hypertrophy (B)</p> Signup and view all the answers

Which research article is associated with documenting cardiomyocyte renewal in the human heart?

<p>Bergmann et al. 2009, Science (D)</p> Signup and view all the answers

In the study by Waring et al. 2014, what was the outcome of exercise training on maximal exercising capacity?

<p>Improved capacity (A)</p> Signup and view all the answers

What is the main issue that leads to the ischaemic cascade in the context of coronary regulation?

<p>Decreased levels of ATP (A)</p> Signup and view all the answers

Which factor plays a crucial role in determining coronary blood flow based on shear stress in the coronary arteries?

<p>Shear stress (D)</p> Signup and view all the answers

What happens to cellular ATP levels when there is cellular hypoxia in cardiac tissue?

<p>ATP levels decrease (C)</p> Signup and view all the answers

Which condition is a direct consequence of abnormal relaxation in cardiac cells during the ischaemic cascade?

<p>Angina (B)</p> Signup and view all the answers

What is the primary factor responsible for adequate vasodilation in response to increased metabolic demand in the heart?

<p>Metabolic control (D)</p> Signup and view all the answers

In the context of coronary autoregulation, what role does shear stress play in maintaining blood flow dynamics?

<p>Encourages metabolic vasodilation (B)</p> Signup and view all the answers

How do wall motion abnormalities contribute to the ischaemic cascade development?

<p>By causing abnormal relaxation (B)</p> Signup and view all the answers

Why is it essential for cellular ATP levels to match the metabolic demand of the heart?

<p>To avoid cellular hypoxia (C)</p> Signup and view all the answers

Which factor plays a critical role in determining coronary blood flow based on metabolic needs in the heart?

<p>Mitochondrial activity (A)</p> Signup and view all the answers

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