Cardiac Cellular Homeostasis and Myocyte Renewal Quiz
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Questions and Answers

What is the main focus of the study by Bergmann et al. 2009?

  • Cardiomyocyte renewal in the human heart (correct)
  • The post-mitotic nature of the adult heart
  • The role of stem cells in the heart
  • The effect of exercise on cardiac growth
  • Which of the following parameters was NOT used to categorize rats in the study by Waring et al. 2014?

  • Type of exercise
  • Age (correct)
  • Level of intensity
  • Control group
  • What is the main cellular component responsible for contraction in the heart?

  • Stem Cells
  • Cardiomyocytes (correct)
  • Extracellular Matrix
  • Vasculature
  • What type of growth was induced by high-intensity exercise training in rats?

    <p>Concentric hypertrophy</p> Signup and view all the answers

    Which research article is associated with documenting cardiomyocyte renewal in the human heart?

    <p>Bergmann et al. 2009, Science</p> Signup and view all the answers

    In the study by Waring et al. 2014, what was the outcome of exercise training on maximal exercising capacity?

    <p>Improved capacity</p> Signup and view all the answers

    What is the main issue that leads to the ischaemic cascade in the context of coronary regulation?

    <p>Decreased levels of ATP</p> Signup and view all the answers

    Which factor plays a crucial role in determining coronary blood flow based on shear stress in the coronary arteries?

    <p>Shear stress</p> Signup and view all the answers

    What happens to cellular ATP levels when there is cellular hypoxia in cardiac tissue?

    <p>ATP levels decrease</p> Signup and view all the answers

    Which condition is a direct consequence of abnormal relaxation in cardiac cells during the ischaemic cascade?

    <p>Angina</p> Signup and view all the answers

    What is the primary factor responsible for adequate vasodilation in response to increased metabolic demand in the heart?

    <p>Metabolic control</p> Signup and view all the answers

    In the context of coronary autoregulation, what role does shear stress play in maintaining blood flow dynamics?

    <p>Encourages metabolic vasodilation</p> Signup and view all the answers

    How do wall motion abnormalities contribute to the ischaemic cascade development?

    <p>By causing abnormal relaxation</p> Signup and view all the answers

    Why is it essential for cellular ATP levels to match the metabolic demand of the heart?

    <p>To avoid cellular hypoxia</p> Signup and view all the answers

    Which factor plays a critical role in determining coronary blood flow based on metabolic needs in the heart?

    <p>Mitochondrial activity</p> Signup and view all the answers

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