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Cardiac Biomarker

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5 Questions

Why are cardiac biomarkers important in the management of patients presenting with chest pain?

They are used for the diagnosis and risk stratification of patients with suspected acute coronary syndrome (ACS).

What are the conditions in which cardiac biomarkers are used for prognosis besides acute coronary syndrome?

Acute heart failure and pulmonary embolism.

Describe the role of cardiac biomarkers in diagnosing myocardial infarction (MI).

Cardiac biomarkers are released due to damage or death of cardiac myocytes, and measuring these biomarkers in serum or plasma helps in the diagnosis of MI.

List three cardiac enzymes that are measured as myocardial injury markers.

Creatine kinase isoenzyme (CK-MB), Aspartate transaminase (AST), and Lactate dehydrogenase (LDH).

Explain why early detection of cardiovascular diseases (CVDs) is critical.

It is important for prevention and treatment to minimize morbidity and mortality.

Study Notes

Cardiac Biomarkers

  • Cardiovascular diseases (CVDs) are a major healthcare burden worldwide.
  • Early detection of CVDs is crucial in preventing and treating to minimize morbidity and mortality.

Uses of Cardiac Markers

  • Cardiac markers are used to diagnose and risk-stratify patients with chest pain and suspected acute coronary syndrome (ACS).
  • They are also used to manage and predict outcomes in patients with acute heart failure, pulmonary embolism, and other diseases.

Cardiac Biomarkers: Release and Significance

  • Cardiac biomarkers are released into the circulation due to cardiac myocyte damage or death.
  • Measuring these biomarkers in serum or plasma helps diagnose myocardial infarction (MI).

Myocardial Injury Markers

  • Cardiac enzymes are used to diagnose myocardial injury.
  • Examples of cardiac enzymes include:
    • Creatine kinase isoenzyme (CK-MB)
    • Aspartate transaminase (AST)
    • Lactate dehydrogenase (LDH)

Learn about the role of cardiac biomarkers in diagnosing and managing cardiovascular diseases, including acute coronary syndrome and heart failure.

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