Cardiac Action Potential: Plateau Phase Importance
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Questions and Answers

During which phase of the cardiac action potential do the Na+ channels close, preventing further action potential production?

  • Phase 1: early repolarization
  • Phase 3: rapid repolarization
  • Phase 2: plateau phase
  • Phase 0: rapid depolarization (correct)
  • Which phase of the cardiac action potential is referred to as the 'absolute refractory period'?

  • Phase 3: rapid repolarization
  • Phase 2: plateau phase (correct)
  • Phase 1: early repolarization
  • Phase 4: resting phase
  • What is a characteristic of the 'relative refractory period' in the cardiac action potential?

  • Resting potential is significantly altered
  • Na+ channels have fully re-opened
  • Action potential generation is inhibited (correct)
  • Phase 0 requires less stimulation
  • Which phase of the cardiac action potential marks the transition from depolarization to repolarization?

    <p>Phase 1: early repolarization</p> Signup and view all the answers

    What happens to the Na+ channels during the plateau phase of the cardiac action potential?

    <p>They remain closed</p> Signup and view all the answers

    In which phase of the cardiac action potential does repolarization occur?

    <p>Phase 3: rapid repolarization</p> Signup and view all the answers

    What characterizes phase 0 of the cardiac action potential?

    <p>Opening of sodium gates leading to rapid depolarization</p> Signup and view all the answers

    Which phase of the cardiac action potential is characterized by a hundred-fold increase in sodium permeability?

    <p>Phase 0: Rapid depolarization</p> Signup and view all the answers

    What is the defining feature of phase 1 in the cardiac action potential?

    <p>Rapid, partial early repolarization</p> Signup and view all the answers

    During which phase of the cardiac action potential does the plateau phase occur?

    <p>Phase 2: Plateau phase</p> Signup and view all the answers

    Which phase marks the complete repolarization in the cardiac action potential?

    <p>Phase 2: Plateau phase</p> Signup and view all the answers

    At what membrane potential does the resting phase (phase 4) occur in cardiac myocytes?

    <p>-85 mV</p> Signup and view all the answers

    During which phase of the cardiac action potential does Na+ influx take place down its electrochemical gradient?

    <p>Phase 0: rapid depolarization</p> Signup and view all the answers

    Which phase is characterized by the membrane potential rising to between +20 and +30 mV?

    <p>Phase 0: rapid depolarization</p> Signup and view all the answers

    What causes the membrane potential to fall to a value close to the potassium equilibrium potential in phase 3?

    <p>Increased K+ channel opening</p> Signup and view all the answers

    Which event causes the release of a larger quantity of Ca++ from the sarcoplasmic reticulum in the cardiac action potential cycle?

    <p>Simultaneous opening of L-type voltage gated calcium channels</p> Signup and view all the answers

    Which phase is characterized by K+ permeability beginning to increase and K+ leaving the cell at an increased rate?

    <p>Phase 1: early repolarization</p> Signup and view all the answers

    At which stage of the cardiac action potential cycle does the membrane potential begin again from the resting potential?

    <p>Phase 4: resting phase</p> Signup and view all the answers

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