Podcast
Questions and Answers
What is the primary function of carbohydrates in living organisms?
What is the primary function of carbohydrates in living organisms?
- Act as a source of energy (correct)
- Form hormonal signals
- Provide genetic information
- Serve as cellular receptors
What distinguishes aldoses from ketoses?
What distinguishes aldoses from ketoses?
- The position of the hydroxyl group
- The number of carbon atoms
- The type of carbonyl group present (correct)
- The ability to form polysaccharides
Which of the following is a structural characteristic of monosaccharides?
Which of the following is a structural characteristic of monosaccharides?
- They are always found in linear form
- They are larger than polysaccharides
- They have a general formula of Cn(Hâ‚‚O)n (correct)
- They contain one asymmetric carbon only
Which type of carbohydrate is formed by the linkage of two monosaccharides?
Which type of carbohydrate is formed by the linkage of two monosaccharides?
What term describes carbohydrates that differ in configuration around only one asymmetric carbon?
What term describes carbohydrates that differ in configuration around only one asymmetric carbon?
What type of ring structures can fructose form during cyclization?
What type of ring structures can fructose form during cyclization?
In the D and L nomenclature system, which carbon is referenced to determine the configuration?
In the D and L nomenclature system, which carbon is referenced to determine the configuration?
Which of the following carbohydrates serves as a structural component in cell walls?
Which of the following carbohydrates serves as a structural component in cell walls?
What is the result of oxidizing aldoses with Tollen's reagent?
What is the result of oxidizing aldoses with Tollen's reagent?
Which reaction is responsible for converting an aldose to an alditol?
Which reaction is responsible for converting an aldose to an alditol?
What type of acid is formed when aldoses are oxidized to the carbonyl group?
What type of acid is formed when aldoses are oxidized to the carbonyl group?
The formation of an osazone is primarily associated with which functional group?
The formation of an osazone is primarily associated with which functional group?
What type of configuration do pyranose sugars usually assume?
What type of configuration do pyranose sugars usually assume?
Which of the following correctly describes exhaustive methylation in carbohydrate chemistry?
Which of the following correctly describes exhaustive methylation in carbohydrate chemistry?
Which statement correctly describes an anomer of glucose?
Which statement correctly describes an anomer of glucose?
What is the characteristic product resulting from glycoside formation?
What is the characteristic product resulting from glycoside formation?
What reaction forms an intramolecular hemiacetal in glucose?
What reaction forms an intramolecular hemiacetal in glucose?
What is the role of HNO3 in carbohydrate oxidation?
What is the role of HNO3 in carbohydrate oxidation?
Which of the following tests indicates the presence of reducing sugars?
Which of the following tests indicates the presence of reducing sugars?
What defines a sugar alcohol?
What defines a sugar alcohol?
What happens to the aldehyde group in sugar acids?
What happens to the aldehyde group in sugar acids?
How does N-acetylneuraminic acid affect glycoproteins?
How does N-acetylneuraminic acid affect glycoproteins?
What is formed when an amino group substitutes for a hydroxyl group in sugars?
What is formed when an amino group substitutes for a hydroxyl group in sugars?
What is the primary function of sugar phosphates in biochemistry?
What is the primary function of sugar phosphates in biochemistry?
What is the length of GAG chains in proteoglycans?
What is the length of GAG chains in proteoglycans?
How do GAG gels function within the extracellular matrix?
How do GAG gels function within the extracellular matrix?
Which of the following describes the immune response to foreign blood group antigens?
Which of the following describes the immune response to foreign blood group antigens?
What is the major component of cartilage mentioned in the content?
What is the major component of cartilage mentioned in the content?
What type of protein does decorin associate with in the extracellular matrix?
What type of protein does decorin associate with in the extracellular matrix?
What is the primary function of peptidoglycan in bacterial cells?
What is the primary function of peptidoglycan in bacterial cells?
What distinguishes glycoproteins from proteoglycans?
What distinguishes glycoproteins from proteoglycans?
Which statement is true regarding glycosaminoglycans (GAGs)?
Which statement is true regarding glycosaminoglycans (GAGs)?
Which of the following is a significant role of proteoglycans in animal cells?
Which of the following is a significant role of proteoglycans in animal cells?
What percentage of carbohydrates by weight can proteoglycans contain?
What percentage of carbohydrates by weight can proteoglycans contain?
What is a common structural characteristic of glycoproteins?
What is a common structural characteristic of glycoproteins?
Which sugar derivatives are commonly found in the repeating units of glycosaminoglycans?
Which sugar derivatives are commonly found in the repeating units of glycosaminoglycans?
What effect does penicillin have on bacterial cell walls?
What effect does penicillin have on bacterial cell walls?
What type of linkage is found in sucrose?
What type of linkage is found in sucrose?
Which term describes the type of bond linking two monosaccharides in a disaccharide?
Which term describes the type of bond linking two monosaccharides in a disaccharide?
What is the full name of lactose?
What is the full name of lactose?
Which structural component contributes to the negative charge of sugar sulfates at physiological pH?
Which structural component contributes to the negative charge of sugar sulfates at physiological pH?
What does a ketal of fructose form?
What does a ketal of fructose form?
Which type of saccharides provide structural integrity to organisms?
Which type of saccharides provide structural integrity to organisms?
What distinguishes a homopolysaccharide from a heteropolysaccharide?
What distinguishes a homopolysaccharide from a heteropolysaccharide?
Which disaccharide is derived from starch and linked by an α(1→4) glycosidic bond?
Which disaccharide is derived from starch and linked by an α(1→4) glycosidic bond?
Flashcards
Pentoses and hexoses cyclize
Pentoses and hexoses cyclize
Pentoses and hexoses form cyclic structures by reacting the ketone or aldehyde group with a distal hydroxyl.
Anomers
Anomers
Isomers of a cyclic sugar that differ only in the position of the hydroxyl group at the anomeric carbon.
Haworth projections
Haworth projections
Representations that depict cyclic sugars as nearly planar rings.
Intramolecular hemiacetal
Intramolecular hemiacetal
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Pyranose ring
Pyranose ring
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Sugar alcohols
Sugar alcohols
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Sugar acids
Sugar acids
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Deoxysugars
Deoxysugars
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Carbohydrates
Carbohydrates
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Monosaccharides
Monosaccharides
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Aldoses
Aldoses
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Ketoses
Ketoses
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Cyclization
Cyclization
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D and L stereoisomers
D and L stereoisomers
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Hemiacetal/Hemiketal Formation
Hemiacetal/Hemiketal Formation
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Mutarotation
Mutarotation
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Oxidation of Sugars
Oxidation of Sugars
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Aldonic Acid
Aldonic Acid
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Reducing Sugars
Reducing Sugars
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Reduction of Aldoses
Reduction of Aldoses
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Osazone Formation
Osazone Formation
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Glycoside Formation
Glycoside Formation
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Esterification of Sugars
Esterification of Sugars
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Glycosidic bond
Glycosidic bond
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Disaccharides
Disaccharides
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Maltose: Structure
Maltose: Structure
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Sucrose: Structure
Sucrose: Structure
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Lactose: Structure
Lactose: Structure
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Homopolysaccharides
Homopolysaccharides
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Heteropolysaccharides
Heteropolysaccharides
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What is a proteoglycan?
What is a proteoglycan?
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What are glycosaminoglycans (GAGs)?
What are glycosaminoglycans (GAGs)?
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What is the role of proteoglycans in the extracellular matrix (ECM)?
What is the role of proteoglycans in the extracellular matrix (ECM)?
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How do proteoglycans contribute to ECM structural integrity?
How do proteoglycans contribute to ECM structural integrity?
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Blood Group Antigens
Blood Group Antigens
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Peptidoglycan
Peptidoglycan
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What does penicillin inhibit?
What does penicillin inhibit?
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Glycosaminoglycans (GAGs)
Glycosaminoglycans (GAGs)
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Proteoglycans
Proteoglycans
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Glycoproteins
Glycoproteins
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N-linkage
N-linkage
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O-linkage
O-linkage
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Distinguishing feature of proteoglycans
Distinguishing feature of proteoglycans
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Study Notes
Carbohydrates
- Carbohydrates are compounds containing carbon, hydrogen, and oxygen
- They are crucial for energy storage, metabolic processes, and structural components in living organisms.
- Common formula: Cn(H2O)n
- Different classifications of carbohydrates include simple, oligosaccharide and complex, polysaccharides
Monosaccharides
- Simplest form of carbohydrates
- Aldoses have an aldehyde group, and ketoses have a ketone group
- Classified by the number of carbon atoms (trioses, tetroses, pentoses, hexoses, heptoses)
- Examples include glucose, fructose, galactose
Stereoisomers
- D and L isomers are determined based on the configuration around the asymmetric carbon farthest from the aldehyde/ketone group in glyceraldehyde.
- Epimers differ in configuration around only one chiral center.
Nomenclature of Monosaccharides
- Based on the number of carbon atoms and the functional group (aldehyde or ketone)
- Examples of monosaccharide names include glyceraldehyde, erythrose, ribose, glucose, fructose, mannose.
Cyclization of Sugars
- Monosaccharides can form cyclic structures (hemiacetals or hemiketals) through intramolecular reactions.
- This cyclization creates anomeric carbons (new chiral center) resulting in α and β anomers that differ in the position of the hydroxyl group at the anomeric carbon.
- Haworth projections are used to visualize the cyclic forms.
Sugar Derivatives
- Sugar alcohols are formed by reduction of the carbonyl group
- Sugar acids are formed by oxidation of the aldehyde or ketone group.
- Deoxy sugars have a hydroxyl group replaced by a hydrogen.
Reactions of Monosaccharides
- Mutarotation, a change in the specific rotation of a sugar solution is the interconversion of the cyclic forms (α to β and vice versa)
- Oxidation by chemicals (e.g., bromine water) or strong oxidizing agents such as nitric acid can further breakdown the carbon backbone, forming sugar acids
- Osazone formation is a reaction that can differentiate between different ketoses.
Disaccharides
- Composed of two monosaccharide units joined by a glycosidic bond.
- Formation of glycosidic bonds involves the loss of a water molecule.
- Examples include sucrose, maltose, lactose, cellobiose
Polysaccharides
- Long chains of monosaccharides linked by glycosidic bonds
- Can be branched or unbranched
- Examples include starch, glycogen, cellulose, and chitin.
Other Carbohydrates
- Peptidoglycan, a polymer that forms bacterial cell walls.
- Glycoproteins and proteoglycans are proteins with covalently attached carbohydrate chains.
- Glycosaminoglycans are long unbranched polysaccharides containing repeating disaccharide units.
- Blood group antigens, which are oligosaccharides that are important in blood transfusions.
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