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Questions and Answers
What are hard gelatin capsules made of?
What are hard gelatin capsules made of?
What is the advantage of hard gelatin capsules?
What is the advantage of hard gelatin capsules?
What is a disadvantage of hard gelatin capsules?
What is a disadvantage of hard gelatin capsules?
What permits a wide prescribing opportunity by the physician in relation to hard gelatin capsules?
What permits a wide prescribing opportunity by the physician in relation to hard gelatin capsules?
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What do hard gelatin capsules allow for in terms of dispensing powders?
What do hard gelatin capsules allow for in terms of dispensing powders?
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What are hard gelatin capsules essentially according to the text?
What are hard gelatin capsules essentially according to the text?
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What is the primary purpose of adding titanium dioxide to the gelatin mixture?
What is the primary purpose of adding titanium dioxide to the gelatin mixture?
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Which type of gelatin is mainly manufactured from animal bones?
Which type of gelatin is mainly manufactured from animal bones?
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What contributes to the firmness of gelatin capsules?
What contributes to the firmness of gelatin capsules?
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What is the primary method for manufacturing hard gelatin capsule shells?
What is the primary method for manufacturing hard gelatin capsule shells?
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What happens to gelatin capsules in high humidity conditions?
What happens to gelatin capsules in high humidity conditions?
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What is the primary purpose of plasticizers in soft gelatin capsules?
What is the primary purpose of plasticizers in soft gelatin capsules?
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In which type of capsule does gelatin rapidly release its contents in gastric fluid?
In which type of capsule does gelatin rapidly release its contents in gastric fluid?
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What do HPMC capsules generally have lower Equilibrium Moisture Content (EMC) than?
What do HPMC capsules generally have lower Equilibrium Moisture Content (EMC) than?
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What distinguishes Type A from Type B gelatin?
What distinguishes Type A from Type B gelatin?
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What happens to hard gelatin capsules in extreme dryness?
What happens to hard gelatin capsules in extreme dryness?
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Study Notes
Composition of Hard Gelatin Capsules
- Hard gelatin capsules are made of gelatin, water, and sometimes other additives such as titanium dioxide, plasticizers, and colorants.
Advantages of Hard Gelatin Capsules
- Hard gelatin capsules allow for flexible prescribing opportunities by physicians due to their availability in various sizes and colors.
Disadvantages of Hard Gelatin Capsules
- A disadvantage of hard gelatin capsules is that they can become brittle and crack in extreme dryness.
Dispensing Powders
- Hard gelatin capsules allow for the dispensing of powders in precise and uniform amounts.
Definition of Hard Gelatin Capsules
- Hard gelatin capsules are essentially a container made of a mixture of gelatin and other additives, molded into a specific shape.
Titanium Dioxide
- The primary purpose of adding titanium dioxide to the gelatin mixture is to provide opacity and whiteness to the capsules.
Type of Gelatin
- Bone gelatin, which is mainly manufactured from animal bones, is often used in the production of hard gelatin capsules.
Firmness of Gelatin Capsules
- The firmness of gelatin capsules is contributed by the water content, which is controlled to achieve the desired level of firmness.
Manufacturing of Hard Gelatin Capsules
- The primary method for manufacturing hard gelatin capsule shells involves dipping metal pins into a gelatin solution and then drying the shells.
Effect of Humidity
- In high humidity conditions, gelatin capsules can absorb moisture and become soft and weak.
Plasticizers in Soft Gelatin Capsules
- The primary purpose of plasticizers in soft gelatin capsules is to enhance their flexibility and prevent them from becoming brittle.
Rapid Release of Contents
- In hard gelatin capsules, gelatin rapidly releases its contents in gastric fluid.
Equilibrium Moisture Content (EMC)
- HPMC (Hydroxypropylmethylcellulose) capsules generally have lower Equilibrium Moisture Content (EMC) than gelatin capsules.
Type A vs. Type B Gelatin
- Type A gelatin is derived from acid-treated raw materials, whereas Type B gelatin is derived from alkaline-treated raw materials.
Effect of Dryness
- In extreme dryness, hard gelatin capsules can become brittle and crack.
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Description
Test your knowledge about capsules, which are solid dosage forms made of gelatin and used to enclose medicinal substances. Learn about the advantages and features of hard gelatin capsules.