Capillary Fluid Exchange and Hemorrhage Response

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Questions and Answers

What is the primary force that tends to force fluid outward through the capillary membrane?

  • Capillary plasma colloid osmotic pressure
  • Interstitial fluid colloid osmotic pressure
  • Interstitial fluid hydrostatic pressure
  • Capillary hydrostatic pressure (correct)

When does the interstitial fluid hydrostatic pressure tend to force fluid outward through the capillary membrane?

  • When it is 5 mm Hg or lower
  • When it is 20 mm Hg or higher
  • When it is positive
  • When it is negative (correct)

What is the role of capillary plasma colloid osmotic pressure in fluid movement through capillary membranes?

  • Tends to cause osmosis of fluid outward
  • Has no influence on fluid movement
  • Tends to force fluid inward (correct)
  • Neutralizes the other forces

What happens if the net filtration pressure is positive?

<p>There will be a net fluid filtration across the capillaries (C)</p> Signup and view all the answers

What is the main consequence of decreased baroreceptor input to the brain?

<p>Increased sympathetic nervous system activation (D)</p> Signup and view all the answers

Which of the following Starling forces leads to osmosis of fluid inward through the capillary membrane?

<p>Capillary plasma colloid osmotic pressure (B)</p> Signup and view all the answers

Which region of the circulation is particularly affected by sympathetic vasoconstriction during hemorrhage?

<p>All of the above (D)</p> Signup and view all the answers

When will there be a net fluid absorption from the interstitial spaces into the capillaries based on Starling forces?

<p>When the sum of forces is negative (A)</p> Signup and view all the answers

Which force primarily drives fluid filtration across the capillary vessel wall?

<p>Blood pressure in the capillaries (A)</p> Signup and view all the answers

What is the purpose of the sympathetically mediated venoconstriction during hemorrhage?

<p>To limit the fall in preload on the right side of the heart (B)</p> Signup and view all the answers

What is the role of starling forces in fluid movement across the capillary wall?

<p>Regulate osmotic gradient between blood and tissue (C)</p> Signup and view all the answers

At what level of blood loss does the sympathetic activation become succeeded by inhibition of sympathetic outflow and progression to circulatory shock?

<p>About 25-35% blood volume loss (C)</p> Signup and view all the answers

How does the brain and coronary circulations respond to sympathetic vasoconstriction during hemorrhage?

<p>They are relatively preserved (B)</p> Signup and view all the answers

In which region of the capillary do forces favoring filtration dominate?

<p>Arterial end (D)</p> Signup and view all the answers

What is the main effect of decreased baroreceptor input on the parasympathetic nerve supply to the heart?

<p>Decreased parasympathetic activity (B)</p> Signup and view all the answers

How does blood loss affect arterial blood pressure?

<p>Decreases arterial blood pressure (B)</p> Signup and view all the answers

What is the purpose of compensatory responses triggered by CVS reflexes after blood loss?

<p>Restore arterial blood pressure (C)</p> Signup and view all the answers

Which organ plays a crucial role in the long-term restoration of blood volume following hemorrhage?

<p>Kidney (B)</p> Signup and view all the answers

What is the function of the precapillary sphincter?

<p>Regulates the blood flow into the capillary (D)</p> Signup and view all the answers

What causes the intermittent periods of capillary blood flow known as vasomotion?

<p>Contractions of metarterioles and precapillary sphincters (D)</p> Signup and view all the answers

What plays a crucial role in determining the degree of opening and closing of metarterioles and precapillary sphincters?

<p>Concentration of oxygen (C)</p> Signup and view all the answers

What does capillary tone refer to?

<p>Percentage of partially and totally closed capillaries at a specific time (C)</p> Signup and view all the answers

How does the local tissue affect the function of metarterioles and precapillary sphincters?

<p>By changing nutrient concentrations (A)</p> Signup and view all the answers

What happens to capillary blood flow when tissue oxygen usage is high and oxygen concentration decreases?

<p>Intermittent periods of capillary blood flow occur more often (B)</p> Signup and view all the answers

What is the expected mean arterial blood pressure range after a 15 – 20% hemorrhage?

<p>80– 90 mm Hg (C)</p> Signup and view all the answers

How does decreased blood volume affect right atrial pressure and cardiac output?

<p>Decreases right atrial pressure and increases cardiac output (D)</p> Signup and view all the answers

What happens to mean arterial pressure when there is a 20% reduction in blood volume?

<p>Decreases (D)</p> Signup and view all the answers

What is the consequence of a blood volume loss of 30 – 40% on mean arterial blood pressure?

<p>Reduction to 50 – 70 mm Hg (C)</p> Signup and view all the answers

Which regulatory mechanism plays a role in restoring blood pressure after hemorrhage?

<p>Carotid sinus baroreceptor reflex (D)</p> Signup and view all the answers

What is the expected cardiac output after a 20% reduction in blood volume?

<p>$3 L/min$ (B)</p> Signup and view all the answers

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