PLS PUMASA KA
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Questions and Answers

What is the role of genomic instability in cancer initiation and progression?

  • It plays an important role in cancer initiation and progression (correct)
  • It has no role in cancer
  • It slows down cancer progression
  • It only affects cancer cells

What are driver mutations in cancer?

  • Genetic alterations that impair cell repair
  • Mutations found at lower frequencies in cancer cells
  • Genetic alterations that provide a growth advantage to cancer cells (correct)
  • Mutations that do not contribute to cancer development

What do passenger mutations refer to in the context of cancer?

  • Genetic alterations that drive cancer growth
  • Mutations found at higher frequencies in cancer cells
  • Genetic alterations that provide a growth advantage
  • Non-essential genetic alterations that do not directly contribute to cancer development (correct)

Which factor can contribute to genetic changes in cancer?

<p>DNA Replication Errors, Age, Inherited and Acquired Mutations (D)</p> Signup and view all the answers

How do BRCA1/BRCA2 mutations increase the risk of breast and ovarian cancers?

<p>By impairing cell repair and causing uncontrolled cell growth (C)</p> Signup and view all the answers

Which genetic mutations have a higher lifetime risk of breast cancer, according to the text?

<p>BRCA1 mutations (A)</p> Signup and view all the answers

What is the main focus of genomics?

<p>Analyzing the genome of an organism (C)</p> Signup and view all the answers

How is gene therapy used in treating diseases?

<p>Introducing functional genes to correct genetic defects (C)</p> Signup and view all the answers

What can affect oncogenes, tumor suppressor genes, and DNA repair genes?

<p>Various changes in biological systems (A)</p> Signup and view all the answers

In gene expression, what process leads to the synthesis of functional gene products?

<p>Utilizing gene information to synthesize proteins or RNA molecules (D)</p> Signup and view all the answers

What defines proteomics as a field of study?

<p>Analyzing all proteins expressed by an organism (C)</p> Signup and view all the answers

Which type of mutation does NOT affect the survival of the organism?

<p>Neutral mutations (C)</p> Signup and view all the answers

Which of the following is an example of a beneficial mutation?

<p>Trichromatic color vision (A)</p> Signup and view all the answers

What type of mutations offer an edge to an organism by boosting its fitness in a particular environment?

<p>Beneficial mutations (D)</p> Signup and view all the answers

What causes the clumping of hemoglobin molecules in sickle cell anemia?

<p>Oxidative mutations (A)</p> Signup and view all the answers

Which population has evolved genetic mutations for continuous lactase production in adulthood?

<p>Population with lactose tolerance (D)</p> Signup and view all the answers

What characterizes deleterious mutations in terms of the gene's protein product?

<p>Produced and disrupting normal function (D)</p> Signup and view all the answers

What is the main focus of secondary structure in proteins?

<p>Local folded structures within a polypeptide (B)</p> Signup and view all the answers

Which structural element is characterized by a flat, sheet-like arrangement of amino acid residues?

<p>Beta-sheet (D)</p> Signup and view all the answers

What type of interaction stabilizes a protein's structure by folding the polypeptide chain to minimize exposure to the surrounding watery environment?

<p>Hydrophobic Interaction (B)</p> Signup and view all the answers

Which type of bond stabilizes the tertiary structure of a protein chain by linking distant parts of the chain?

<p>Disulfide Bridge (D)</p> Signup and view all the answers

What is the role of hydrogen bonds in protein structure?

<p>Stabilizing secondary structure elements (C)</p> Signup and view all the answers

Which interaction stabilizes protein solubility and facilitates interactions with other molecules through hydrophilic interactions on the protein's surface?

<p>Hydrophilic Interaction (C)</p> Signup and view all the answers

What is the primary goal of surgery in cancer treatment?

<p>To prevent further spread by removing the tumor and affected tissues (A)</p> Signup and view all the answers

When is radiation therapy commonly used in cancer treatment?

<p>Before surgery to shrink tumors (B)</p> Signup and view all the answers

What is the main purpose of chemotherapy in cancer treatment?

<p>To destroy cancer cells throughout the body (B)</p> Signup and view all the answers

Which type of therapy specifically targets molecules involved in cancer growth?

<p>Targeted therapy (C)</p> Signup and view all the answers

In which type of cancer treatment is immunotherapy focused on?

<p>Boosting the patient's immune system to fight cancer cells (C)</p> Signup and view all the answers

When might chemotherapy be used as adjuvant therapy?

<p>After surgery to kill any remaining cancer cells (C)</p> Signup and view all the answers

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