Radiation Therapy and Fractionation
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Questions and Answers

What is the main advantage of dividing the high dose of radiation into many fractions in radiation therapy?

  • To deliver the radiation dose more quickly
  • To increase the overall radiation dose
  • To allow healthy cells to recover and repopulate between fractions (correct)
  • To target tumor cells more precisely

What is the primary reason why radiation therapy is especially effective for superficial skin cancers?

  • The skin is more accessible to radiation (correct)
  • The healthy cells have better DNA repair mechanisms
  • The cancer cells are more sensitive to radiation
  • The tumor cells are more easily targeted

What is the main factor that determines the effectiveness of radiation therapy in individual cases?

  • The dose of radiation delivered
  • The frequency of radiation sessions
  • The cancer type and specifics of individual cases (correct)
  • The type of radiation used

What is the purpose of the 'Repopulation' phase in the 4 R's of fractionation?

<p>To allow healthy and malignant cells to repopulate after irradiation (A)</p> Signup and view all the answers

What is the typical dose per fraction in a conventional fractionation scheme?

<p>1.8-2.2 Gy (D)</p> Signup and view all the answers

What is the total dose range for conventional fractionation?

<p>45.0 - 50.4 Gy (C)</p> Signup and view all the answers

Which type of fractionation scheme is used to avoid late normal tissue complications?

<p>Hyper-fractionation (B)</p> Signup and view all the answers

What is the dose per fraction range for accelerated fractionation?

<p>1.4 - 2.5 Gy (C)</p> Signup and view all the answers

What is the main issue with hyper-fractionation?

<p>No clear benefit has been demonstrated (C)</p> Signup and view all the answers

Which of the following factors can be controlled in radiotherapy?

<p>Means of delivering the radiation, radiation type, total dose, fractions, and time between fractions (D)</p> Signup and view all the answers

Why are alpha particles not commonly used in radiotherapy?

<p>Because they have a very short range (B)</p> Signup and view all the answers

What is the main advantage of beam sources in radiotherapy?

<p>They deliver a uniform, well-defined, and stable beam (B)</p> Signup and view all the answers

What has become important in the last 25 years of radiotherapy development?

<p>Computerization and intensity modulated beam delivery (A)</p> Signup and view all the answers

What type of radiation therapy involves sealed radioactive sources placed in proximity to the tumor?

<p>Brachytherapy (D)</p> Signup and view all the answers

What was the goal of radiotherapy development in the first 50 years?

<p>To produce ever higher photon and electron beam energies and intensities (B)</p> Signup and view all the answers

What is the primary purpose of a teletherapy machine?

<p>To contain and control the radiation source (D)</p> Signup and view all the answers

What is the typical diameter of a teletherapy source?

<p>Between 1 and 2 cm (D)</p> Signup and view all the answers

What is the effect of decreasing the source diameter?

<p>Smaller physical penumbra and higher cost (B)</p> Signup and view all the answers

What is the typical dose rate at 80 cm from the teletherapy source?

<p>1-2 Gy/min (D)</p> Signup and view all the answers

Why is a standard source capsule design used?

<p>To enable swapping of sources between machines (A)</p> Signup and view all the answers

What is the term used to describe treatment machines that incorporate gamma ray sources for external beam radiotherapy?

<p>Teletherapy machines (D)</p> Signup and view all the answers

Which of the following is a consideration when selecting a suitable source for teletherapy devices?

<p>Half-life (D)</p> Signup and view all the answers

What is the most widely used teletherapy source?

<p>60Co radionuclides (C)</p> Signup and view all the answers

What is the primary factor that determines the effectiveness of a teletherapy source?

<p>Photon energy (D)</p> Signup and view all the answers

What is the purpose of considering the decay into a more stable daughter nucleus in teletherapy sources?

<p>To ensure the source is stable during treatment (C)</p> Signup and view all the answers

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