18 Questions
Which process accelerates the development of cervical cancer and colon cancer?
Increased proliferation
What is a key requirement for tumor cells in the process of metastasis?
Vascular growth (angiogenesis)
Which external factors are considered as cancer risk factors?
All of the above
What is the purpose of the Ames test in relation to cancer research?
Identify environmental mutagens
How do consecutive cycles of mutations/selections impact cancer development?
Promote the accumulation of genetic changes
What role does decreased cell death (apoptosis) play in the progression of cancer?
Promotes tumor growth
Which process plays an important role in embryogenesis, removal of old epithelial cells, and activated immune cells?
Decreased cell death (apoptosis)
What is the main consequence of polyp formation in the gut?
Increased proliferation in the intestinal epithelium
Which factor contributes to the acceleration of the process in cervical cancer and colon cancer development?
Increased proliferation
What leads to disruption of homeostasis in abnormal cells?
Increased cell division
Which characteristic is a common feature in the accelerated development of cervical and colon cancers?
Increased genetic instability
What factor is responsible for decreased apoptosis in abnormal cells?
Spontaneous mutations
What is the role of HPV infection in the development of cervical cancer?
Inhibition of tumor suppressor genes
Which gene mutation is responsible for the initiation of the adenoma-carcinoma sequence in colon cancer?
Inactivation of APC
What is the consequence of inactivating p53 mutations in cancers?
Apoptosis activation
In the context of cancer development, what is the function of the transcription factor P53?
Promotion of growth arrest
How do oncogenic human papilloma viruses (HPV) contribute to cervical cancer development?
Inhibiting p53 and RB
What is the significance of loss of APC in the Wnt signaling pathway in colon cancer?
Accumulation of beta-catenin
Test your knowledge on the processes that accelerate the progression of cervical and colon cancers, including mutations, genetic instability, decreased apoptosis, increased proliferation, and metastasis formation.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
