Podcast
Questions and Answers
Which of the following best describes the mechanism of action of alkylating agents in cancer treatment?
Which of the following best describes the mechanism of action of alkylating agents in cancer treatment?
- They attach to DNA and prevent it from reproducing properly. (correct)
- They enhance the immune system to target and destroy cancer cells.
- They disrupt critical cell pathways, halting tumor growth.
- They stimulate rapid cell division, overwhelming the cancerous cells.
A patient undergoing chemotherapy with an alkylating agent is concerned about potential side effects. What is a significant long-term side effect that should be discussed?
A patient undergoing chemotherapy with an alkylating agent is concerned about potential side effects. What is a significant long-term side effect that should be discussed?
- Enhanced cardiovascular function.
- Permanent infertility in both males and females. (correct)
- Temporary hair loss.
- Increased appetite and weight gain.
Antimetabolite medications are designed to target which aspect of cancer cell growth?
Antimetabolite medications are designed to target which aspect of cancer cell growth?
- Increasing the rate of protein synthesis in cancer cells.
- Stimulating the cancer cells to differentiate into normal cells.
- Repairing damaged DNA within cancer cells.
- Disrupting critical cell pathways necessary for tumor survival. (correct)
A cancer patient is prescribed an antimetabolite drug. Which administration route is LEAST likely to be used for this type of medication?
A cancer patient is prescribed an antimetabolite drug. Which administration route is LEAST likely to be used for this type of medication?
Antitumor antibiotics, while effective against cancer, are originally derived from what source?
Antitumor antibiotics, while effective against cancer, are originally derived from what source?
Bleomycin is an antitumor antibiotic used to treat specific cancers. Which of the following cancers is it MOST likely to be used for?
Bleomycin is an antitumor antibiotic used to treat specific cancers. Which of the following cancers is it MOST likely to be used for?
Dactinomycin is indicated for treating different types of cancer. Which of the following cancers is LEAST likely to be treated with Dactinomycin?
Dactinomycin is indicated for treating different types of cancer. Which of the following cancers is LEAST likely to be treated with Dactinomycin?
Besides their cytotoxic effects on cancer cells, what other significant adverse effect is associated with certain antitumor antibiotics during cancer treatment?
Besides their cytotoxic effects on cancer cells, what other significant adverse effect is associated with certain antitumor antibiotics during cancer treatment?
Plant extracts, also known as alkaloids, are used in chemotherapy for what primary mechanism?
Plant extracts, also known as alkaloids, are used in chemotherapy for what primary mechanism?
Plant extracts, or alkaloids, target specific types of cancers. Which of the following cancers is LEAST LIKELY to be a target for plant extract-based chemotherapy?
Plant extracts, or alkaloids, target specific types of cancers. Which of the following cancers is LEAST LIKELY to be a target for plant extract-based chemotherapy?
Flashcards
Alkylating Agents
Alkylating Agents
Attach to DNA and prevent it from reproducing normally, effective during all phases of the cell cycle.
Antimetabolite meds
Antimetabolite meds
Disrupt critical cell pathways, used to treat ovarian, breast, GI tumors, and some leukemia
Antitumor Antibiotics
Antitumor Antibiotics
Cause cell death and have potential for cytotoxic effect.
Plant Extracts (Alkaloids)
Plant Extracts (Alkaloids)
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Leukemia- Alkylating Agents
Leukemia- Alkylating Agents
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Side effect of Alkylating Agents
Side effect of Alkylating Agents
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Side effect of Antitumor Antibiotics
Side effect of Antitumor Antibiotics
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Study Notes
- Cancer Meds
Alkylating Agents
- Attach to DNA and prevent it from reproducing
- Effective during all phases of the cell cycle
- Leukemia (blood and bone marrow) is sensitive to them
- Examples include Chlorambucil, Cisplatin, Cyclophosphamide, and Dacarbazine
- Can be administered PO (Orally) or IV (Intravenously)
- Side effect: Permanent infertility, both male and female
Antimetabolite Meds
- Disrupt critical cell pathways
- Treat ovarian, breast, and GI tumors, and some leukemia
- Can be administered PO (Orally), IV (Intravenously), or topically
Antitumor Antibiotics
- Bacteria found in soil are used to create antibiotics to kill cancer
- Cause cell death, although they have potential for cytotoxic effect
- Bleomycin can treat Hodgkin's lymphoma and testicular cancer
- Dactinomycin treats cancer of the kidney, uterus, testicle, bone, muscles, joints, and soft tissues
- Can affect the lungs while treating the cancer
Plant Extracts (Alkaloids)
- Are mitotic inhibitors that prevent cell division
- Soft tissue, breast, ovarian, testicle, stomach, prostate, head, neck, and lung cancer
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