Podcast
Questions and Answers
What triggers the secretion of parathyroid hormone (PTH)?
What triggers the secretion of parathyroid hormone (PTH)?
- A decrease in ionized Ca2+ (correct)
- External calcium intake
- Consistent levels of ionized Ca2+
- An increase in ionized Ca2+
Which process is activated by PTH in the bones?
Which process is activated by PTH in the bones?
- Bone ossification
- Bone remodeling
- Bone calcification
- Bone resorption (correct)
What effect does PTH have on the kidneys?
What effect does PTH have on the kidneys?
- Reduces vitamin D activation
- Enhances tubular reabsorption of Ca2+ (correct)
- Stimulates bone formation
- Increases calcium excretion
What is the action of PTH on vitamin D?
What is the action of PTH on vitamin D?
What hormone is known for opposing the effects of PTH in calcium regulation?
What hormone is known for opposing the effects of PTH in calcium regulation?
Flashcards
Parathyroid hormone (PTH)
Parathyroid hormone (PTH)
A hormone that increases blood calcium levels by stimulating bone resorption and calcium reabsorption in the kidneys.
Bone resorption
Bone resorption
The process where bone cells break down bone tissue, releasing calcium into the bloodstream.
Vitamin D
Vitamin D
A hormone that increases calcium absorption in the intestines, indirectly increasing blood calcium levels.
Calcitonin
Calcitonin
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Tubular reabsorption of calcium
Tubular reabsorption of calcium
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Study Notes
Calcium Regulation
- Three hormones (PTH, vitamin D, calcitonin) regulate serum calcium (Ca2+) levels.
- Their secretion rate changes in response to ionized Ca2+ levels.
- Parathyroid hormone (PTH) secretion increases when ionized Ca2+ decreases, and vice versa.
- PTH affects bone and kidneys.
- In bone, PTH activates osteoclasts, causing bone resorption and releasing Ca2+ into the extracellular fluid (ECF).
- In kidneys, PTH increases tubular reabsorption of Ca2+ ions, thus conserving calcium.
- PTH also stimulates the kidney to produce active vitamin D.
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