Podcast
Questions and Answers
What effect does an increase in ionized Ca2+ have on PTH secretion?
What effect does an increase in ionized Ca2+ have on PTH secretion?
Which hormone is primarily responsible for bone resorption?
Which hormone is primarily responsible for bone resorption?
How does PTH affect calcium in the kidneys?
How does PTH affect calcium in the kidneys?
What stimulates the secretion of PTH in the blood?
What stimulates the secretion of PTH in the blood?
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What role does PTH have in relation to vitamin D?
What role does PTH have in relation to vitamin D?
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Study Notes
Calcium Regulation by Hormones
- Three hormones—PTH, vitamin D, and calcitonin—control serum calcium (Ca2+) levels.
- They adjust secretion in response to ionized calcium (Ca2+) changes.
- Parathyroid hormone (PTH) secretion increases when ionized Ca2+ levels decrease and decreases when ionized Ca2+ levels rise.
- PTH has key effects on bone and kidneys.
- In bone, PTH activates bone resorption, where osteoclasts break down bone, releasing calcium into the extracellular fluid (ECF).
- In kidneys, PTH promotes calcium reabsorption in tubules.
- PTH also stimulates the kidneys to produce active vitamin D.
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Description
This quiz explores the intricate relationship between three key hormones—PTH, vitamin D, and calcitonin—in regulating serum calcium levels. It details how these hormones respond to changes in ionized calcium and their effects on bones and kidneys. Test your knowledge on calcium homeostasis and the physiological roles of these hormones.
