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Questions and Answers
What is the primary role of calcium channels in smooth and cardiac muscle contractile function?
What is the primary role of calcium channels in smooth and cardiac muscle contractile function?
- Regulation of potassium outflow
- Inhibition of magnesium release
- Stimulation of sodium influx
- Modulation of intracellular calcium concentrations (correct)
What is the functional linkage between beta-adrenergic receptors and calcium channels in the heart?
What is the functional linkage between beta-adrenergic receptors and calcium channels in the heart?
- Stimulation of potassium efflux
- Reduction of sodium channels
- Enhancement of calcium channel activity (correct)
- Inhibition of calcium influx
What is the primary difference between the sites of action of nifedipine and diltiazem or verapamil?
What is the primary difference between the sites of action of nifedipine and diltiazem or verapamil?
- Nifedipine acts on smooth muscle, while diltiazem and verapamil act on the heart
- Nifedipine acts on L-type calcium channels, while diltiazem and verapamil act on T-type calcium channels (correct)
- Nifedipine acts on voltage-gated calcium channels, while diltiazem and verapamil act on ligand-gated calcium channels
- Nifedipine acts on the heart, while diltiazem and verapamil act on smooth muscle
What is the most common side effect of calcium channel blockers?
What is the most common side effect of calcium channel blockers?
Which of the following drugs should not be administered with calcium channel blockers due to the risk of excessive depression of cardiac contractility?
Which of the following drugs should not be administered with calcium channel blockers due to the risk of excessive depression of cardiac contractility?
Do the precautions about administering calcium channel blockers with other drugs apply to all types of calcium channel blockers?
Do the precautions about administering calcium channel blockers with other drugs apply to all types of calcium channel blockers?
What is the main effect of calcium channel blockers on vascular smooth muscle?
What is the main effect of calcium channel blockers on vascular smooth muscle?
What is the primary site of action of dihydropyridines?
What is the primary site of action of dihydropyridines?
What is the effect of verapamil on the SA node?
What is the effect of verapamil on the SA node?
What is a common side effect of verapamil in older adults?
What is a common side effect of verapamil in older adults?
What is the therapeutic use of verapamil in cardiac dysrhythmias?
What is the therapeutic use of verapamil in cardiac dysrhythmias?
What is the net effect of verapamil on cardiac performance?
What is the net effect of verapamil on cardiac performance?
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