Calcitriol Flashcards

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Questions and Answers

What is another name for Calcitriol?

  • Rocaltrol (correct)
  • Vitamin D3
  • Calcijex (correct)
  • Calcium supplement

What is the therapeutic class of Calcitriol?

Vitamin D

What is the pharmacologic class of Calcitriol?

Bone resorption inhibitor

What are the primary actions and uses of Calcitriol?

<p>Promotes intestinal absorption of calcium and elevates serum calcium levels.</p> Signup and view all the answers

Calcitriol is available in oral tablets, solutions, and by the _____ route.

<p>IV</p> Signup and view all the answers

What should be done at the first sign of hypercalcemia in a patient being treated with vitamin D?

<p>Discontinue vitamin D therapy and obtain daily serum calcium levels.</p> Signup and view all the answers

Calcitriol is contraindicated in patients with hypercalcemia.

<p>True (A)</p> Signup and view all the answers

What are some early symptoms of hypercalcemia?

<p>Nausea (A), Confusion (B), Weakness (D)</p> Signup and view all the answers

Pregnancy category of Calcitriol is _____

<p>C</p> Signup and view all the answers

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Study Notes

Calcitriol Overview

  • Also known by brand names Calcijex and Rocaltrol.
  • Is the active form of vitamin D, essential for calcium absorption.

Therapeutic Class

  • Classified under Vitamin D.

Pharmacologic Class

  • Functions as a bone resorption inhibitor, essential for maintaining bone health.

Actions and Uses

  • Promotes intestinal absorption of calcium, increasing serum calcium levels.
  • Indicated for conditions like chronic kidney disease (CKD) and hypoparathyroidism.
  • Reduces bone resorption; used off-label to treat rickets.
  • Efficacy hinges on sufficient calcium intake; often combined with calcium supplements.
  • Available in oral tablet, oral solution, and intravenous routes.

Administration Alerts

  • Protect capsules from light and heat to maintain efficacy.
  • Classified as pregnancy category C, suggesting potential risks during pregnancy.

Adverse Effects

  • Overdosage may lead to hypercalcemia, with early symptoms including weakness, confusion, anorexia, nausea, and vomiting.
  • Advanced symptoms may manifest as increased urination, dysrhythmias, dehydration, and weight loss.
  • Immediate discontinuation of therapy at the first signs of hypercalcemia; monitor serum calcium levels regularly until levels normalize.

Contraindications

  • Not suitable for individuals with hypercalcemia or signs of vitamin D toxicity.

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