Neural Tube and Spinal Cord Development

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Questions and Answers

The neuroepithelial cells that form the neural tube ______ towards the periphery.

divide

The neural tube and spinal cord are derived from a single cell layer of ______.

ectoderm

The neural tube and spinal cord are derived from a single cell layer of ______.

ectoderm

At the T1-L2 spinal levels, the basal plate will also give rise to a ______ horn.

<p>lateral</p> Signup and view all the answers

The mantle zone can be divided into a ______ and a ventral basal plate.

<p>dorsal alar plate</p> Signup and view all the answers

The outer white matter of the CNS is called the ______ zone.

<p>marginal</p> Signup and view all the answers

After the CNS is mature, the ventricular layer will differentiate into ______.

<p>ependymal cells</p> Signup and view all the answers

After the CNS is mature, the ventricular layer will differentiate into ______ cells.

<p>ependymal</p> Signup and view all the answers

After the CNS is mature, the ventricular layer will ______ into ependymal cells.

<p>differentiate</p> Signup and view all the answers

Flashcards

Neuroepithelial cells do what?

Cells that form the neural tube multiply.

Neural tube origin cell layer?

Ectoderm

Basal plate gives rise to what horn?

Lateral

Mantle zone division?

Dorsal alar plate

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Outer CNS white matter zone?

Marginal

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Mature ventricular layer cells?

Ependymal cells

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Ventricular layer action?

Differentiate

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Study Notes

  • The neural tube and spinal cord are derived from a single cell layer of ectoderm.
  • The neuroepithelial cells that form the neural tube divide and move towards the periphery of the tube.
  • The neuroblasts that form in the neuroepithelial cells differentiate into neurons and grey matter.
  • The outer white matter of the CNS is called the marginal zone.
  • The grey matter of the CNS is called the mantle zone.
  • The mantle zone can be divided into a dorsal alar plate (which will become the dorsal horn, which contains mostly second-order sensory neuron cell bodies) and a ventral basal plate (which will become the ventral horn, and contains the cell bodies of somatic motor neurons (= lower motor neurons).
  • At the T1-L2 spinal levels, the basal plate will also give rise to a lateral horn, which contains the cell bodies of preganglionic sympathetic neurons.
  • The ventricular layer is the deepest layer, and surrounds the central canal.
  • The ventricular layer is also referred to as the ependymal zone.
  • After the CNS is mature, the ventricular layer will differentiate into ependymal cells.

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