Neural Tube and Spinal Cord Development

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9 Questions

The neuroepithelial cells that form the neural tube ______ towards the periphery.

divide

The neural tube and spinal cord are derived from a single cell layer of ______.

ectoderm

The neural tube and spinal cord are derived from a single cell layer of ______.

ectoderm

At the T1-L2 spinal levels, the basal plate will also give rise to a ______ horn.

lateral

The mantle zone can be divided into a ______ and a ventral basal plate.

dorsal alar plate

The outer white matter of the CNS is called the ______ zone.

marginal

After the CNS is mature, the ventricular layer will differentiate into ______.

ependymal cells

After the CNS is mature, the ventricular layer will differentiate into ______ cells.

ependymal

After the CNS is mature, the ventricular layer will ______ into ependymal cells.

differentiate

Study Notes

  • The neural tube and spinal cord are derived from a single cell layer of ectoderm.
  • The neuroepithelial cells that form the neural tube divide and move towards the periphery of the tube.
  • The neuroblasts that form in the neuroepithelial cells differentiate into neurons and grey matter.
  • The outer white matter of the CNS is called the marginal zone.
  • The grey matter of the CNS is called the mantle zone.
  • The mantle zone can be divided into a dorsal alar plate (which will become the dorsal horn, which contains mostly second-order sensory neuron cell bodies) and a ventral basal plate (which will become the ventral horn, and contains the cell bodies of somatic motor neurons (= lower motor neurons).
  • At the T1-L2 spinal levels, the basal plate will also give rise to a lateral horn, which contains the cell bodies of preganglionic sympathetic neurons.
  • The ventricular layer is the deepest layer, and surrounds the central canal.
  • The ventricular layer is also referred to as the ependymal zone.
  • After the CNS is mature, the ventricular layer will differentiate into ependymal cells.

Test your knowledge of the development of the neural tube and spinal cord with this quiz. Learn about the differentiation of neuroepithelial cells, the formation of grey and white matter, and the differentiation of the ventricular layer into ependymal cells.

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