C-NCM 106 Pharmacology Module 6 Quiz

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Questions and Answers

What is the primary focus of Module 6 in the Pharmacology course?

  • Understanding the physiology of inflammation and pain (correct)
  • Learning about the side effects of anti-inflammatory drugs
  • Identifying different types of antibiotics
  • Exploring the history of pain management

What is the main goal at the close of the allotted time for students in Module 6?

  • Identifying important information about common medications
  • Tracing a simple diagram for inflammatory conditions
  • Discussing different classifications of drugs used in managing inflammation and pain (correct)
  • Describing the side effects of anti-inflammatory drugs

Which activity is included in the self-directed learning for Module 6?

  • Identifying important information about common medications (correct)
  • Analyzing different types of painkillers
  • Creating a concept map from a video on antibiotics
  • Tracing a diagram for opioid medications

What is the key focus when discussing different classifications of drugs used in managing inflammation and pain?

<p>Providing salient information emphasizing on nursing consideration (B)</p> Signup and view all the answers

What is the primary purpose of Module 6's discussion on anti-inflammatory drugs?

<p>To provide an overview and understanding of inflammation (B)</p> Signup and view all the answers

What is NOT a part of the mapped learning outcomes for Module 6?

<p>Highlighting the historical context of pain management (D)</p> Signup and view all the answers

What is the main cause of increased capillary permeability and pain in inflammation?

<p>Kinins (C)</p> Signup and view all the answers

Which enzyme is responsible for converting arachidonic acid into prostaglandins and their products?

<p>Cyclooxygenase (A)</p> Signup and view all the answers

What is the main function of anti-inflammatory drugs?

<p>Relieve pain and reduce elevated body temperature (D)</p> Signup and view all the answers

Which phase of inflammation is associated with vasodilation and increased capillary permeability?

<p>Vascular phase (C)</p> Signup and view all the answers

Which substance protects the stomach lining and regulates blood platelets?

<p>COX-1 (B)</p> Signup and view all the answers

Which inhibits the enzyme COX, needed for the biosynthesis of prostaglandins?

<p>Aspirin-like drugs (C)</p> Signup and view all the answers

What causes fever and sensitization of nerve cells to pain in inflammation?

<p>Prostaglandins (D)</p> Signup and view all the answers

What is the main effect of prostaglandin synthesis at a tissue injury site?

<p>Increase in inflammation and pain (A)</p> Signup and view all the answers

Which response to tissue injury is related to the release of histamines, kinins, and prostaglandins?

<p>(a) Redness (erythema) (A)</p> Signup and view all the answers

What do nonsteroidal anti-inflammatory drugs primarily relieve?

<p>Pain and fever (C)</p> Signup and view all the answers

Which type of drug interferes with the cell cycle to exert its therapeutic effect against cancer?

<p>Antimetabolites (C)</p> Signup and view all the answers

What is the primary function of alkylating agents in the management of cancer?

<p>Cause DNA cross-linking in cancer cells (D)</p> Signup and view all the answers

Which classification of antineoplastic agent mimics the structure of natural metabolites to interfere with metabolic processes in cancer cells?

<p>Antimetabolites (C)</p> Signup and view all the answers

What is a common side effect of hormonal agents used as antineoplastic agents?

<p>Hot flashes and mood swings (D)</p> Signup and view all the answers

Which adverse reaction is specifically associated with antibiotic agents used as antineoplastic agents?

<p>Nephrotoxicity (B)</p> Signup and view all the answers

How do plant alkaloids exert their therapeutic effect against cancer cells?

<p>Prevent microtubule formation in cancer cells (B)</p> Signup and view all the answers

What role does DNA play in cancer?

<p>It acts as a genetic substance in body cells and transfers information necessary for the production of enzymes and protein synthesis (C)</p> Signup and view all the answers

What is the primary action of cell cycle-nonspecific drugs (CCNS)?

<p>Act during any phase of the cell cycle, including the G0 phase (B)</p> Signup and view all the answers

What is the role of the nurse in anticancer therapy?

<p>Administering chemotherapy with appropriate health education (A)</p> Signup and view all the answers

What is the effect of high dose chemotherapy on tumors?

<p>Results in better tumoricidal effects (D)</p> Signup and view all the answers

Why are anticancer agents more effective against small, fast-growing tumors with sufficient blood supply?

<p>Because they have a high growth fraction (A)</p> Signup and view all the answers

What is the role of chemotherapy in cancer treatment?

<p>Chemotherapy is the use of chemicals to kill cancer cells (C)</p> Signup and view all the answers

What type of drugs exert their influence during a specific phase or phases of the cell cycle?

<p>Cell cycle-specific drugs (CCS) / Phase specific drugs (C)</p> Signup and view all the answers

What is the primary mechanism of action for antimetabolites and Vinca alkaloids?

<p>Inhibit DNA synthesis (D)</p> Signup and view all the answers

Why are solid tumors generally less sensitive to anticancer drugs?

<p>They have a large percentage of their cell mass in the G0 phase and thus generally have a low growth fraction (D)</p> Signup and view all the answers

What is the primary factor that results in better tumoricidal effects with high dose chemotherapy?

<p>Small, fast-growing tumors with sufficient blood supply (C)</p> Signup and view all the answers

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Study Notes

Module 6 in Pharmacology

  • Primary focus: Pharmacology of inflammation and pain management
  • Main goal: Understand the classifications and mechanisms of action of drugs used to manage inflammation and pain

Inflammation and Pain Management

  • Key focus: Classifications of drugs used to manage inflammation and pain
  • Primary purpose of discussing anti-inflammatory drugs: Understand their mechanisms of action and effects on prostaglandins

Mechanisms of Inflammation

  • Main cause of increased capillary permeability and pain: Release of histamine, kinins, and prostaglandins
  • Enzyme responsible for converting arachidonic acid into prostaglandins: Cyclooxygenase (COX)
  • Main function of anti-inflammatory drugs: Inhibit prostaglandin synthesis to reduce inflammation and pain

Prostaglandins and Inflammation

  • Main effect of prostaglandin synthesis at a tissue injury site: Vasodilation and increased capillary permeability
  • Phase of inflammation associated with vasodilation and increased capillary permeability: Inflammatory response
  • Substance that protects the stomach lining and regulates blood platelets: Prostaglandins

Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)

  • Main effect: Inhibit COX to reduce prostaglandin synthesis and relieve pain and inflammation
  • Primary relief: Pain and inflammation

Antineoplastic Agents

  • Function of alkylating agents: Interfere with DNA replication to exert therapeutic effect against cancer
  • Primary function of antimetabolites and Vinca alkaloids: Interfere with DNA synthesis and cell cycle progression
  • Role of DNA in cancer: Essential for cancer cell growth and proliferation
  • Primary action of cell cycle-nonspecific drugs (CCNS): Inhibit DNA synthesis and cell proliferation
  • Role of the nurse in anticancer therapy: Monitor and manage side effects, provide supportive care

Cancer Treatment

  • Effect of high dose chemotherapy on tumors: Increased tumoricidal effects
  • Reason why anticancer agents are more effective against small, fast-growing tumors: Better blood supply and increased sensitivity to drugs
  • Role of chemotherapy in cancer treatment: Destroy cancer cells and alleviate symptoms
  • Type of drugs that exert their influence during a specific phase or phases of the cell cycle: Cell cycle-specific drugs

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