32 Questions
What is the primary focus of Module 6 in the Pharmacology course?
Understanding the physiology of inflammation and pain
What is the main goal at the close of the allotted time for students in Module 6?
Discussing different classifications of drugs used in managing inflammation and pain
Which activity is included in the self-directed learning for Module 6?
Identifying important information about common medications
What is the key focus when discussing different classifications of drugs used in managing inflammation and pain?
Providing salient information emphasizing on nursing consideration
What is the primary purpose of Module 6's discussion on anti-inflammatory drugs?
To provide an overview and understanding of inflammation
What is NOT a part of the mapped learning outcomes for Module 6?
Highlighting the historical context of pain management
What is the main cause of increased capillary permeability and pain in inflammation?
Kinins
Which enzyme is responsible for converting arachidonic acid into prostaglandins and their products?
Cyclooxygenase
What is the main function of anti-inflammatory drugs?
Relieve pain and reduce elevated body temperature
Which phase of inflammation is associated with vasodilation and increased capillary permeability?
Vascular phase
Which substance protects the stomach lining and regulates blood platelets?
COX-1
Which inhibits the enzyme COX, needed for the biosynthesis of prostaglandins?
Aspirin-like drugs
What causes fever and sensitization of nerve cells to pain in inflammation?
Prostaglandins
What is the main effect of prostaglandin synthesis at a tissue injury site?
Increase in inflammation and pain
Which response to tissue injury is related to the release of histamines, kinins, and prostaglandins?
(a) Redness (erythema)
What do nonsteroidal anti-inflammatory drugs primarily relieve?
Pain and fever
Which type of drug interferes with the cell cycle to exert its therapeutic effect against cancer?
Antimetabolites
What is the primary function of alkylating agents in the management of cancer?
Cause DNA cross-linking in cancer cells
Which classification of antineoplastic agent mimics the structure of natural metabolites to interfere with metabolic processes in cancer cells?
Antimetabolites
What is a common side effect of hormonal agents used as antineoplastic agents?
Hot flashes and mood swings
Which adverse reaction is specifically associated with antibiotic agents used as antineoplastic agents?
Nephrotoxicity
How do plant alkaloids exert their therapeutic effect against cancer cells?
Prevent microtubule formation in cancer cells
What role does DNA play in cancer?
It acts as a genetic substance in body cells and transfers information necessary for the production of enzymes and protein synthesis
What is the primary action of cell cycle-nonspecific drugs (CCNS)?
Act during any phase of the cell cycle, including the G0 phase
What is the role of the nurse in anticancer therapy?
Administering chemotherapy with appropriate health education
What is the effect of high dose chemotherapy on tumors?
Results in better tumoricidal effects
Why are anticancer agents more effective against small, fast-growing tumors with sufficient blood supply?
Because they have a high growth fraction
What is the role of chemotherapy in cancer treatment?
Chemotherapy is the use of chemicals to kill cancer cells
What type of drugs exert their influence during a specific phase or phases of the cell cycle?
Cell cycle-specific drugs (CCS) / Phase specific drugs
What is the primary mechanism of action for antimetabolites and Vinca alkaloids?
Inhibit DNA synthesis
Why are solid tumors generally less sensitive to anticancer drugs?
They have a large percentage of their cell mass in the G0 phase and thus generally have a low growth fraction
What is the primary factor that results in better tumoricidal effects with high dose chemotherapy?
Small, fast-growing tumors with sufficient blood supply
Test your knowledge of Anti-Inflammatory and Pain Drugs in the C-NCM 106 Pharmacology Module 6. This quiz covers the learning outcomes and course content for the module.
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