Week 12

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30 Questions

What is the lifetime prevalence of Anorexia Nervosa (AN)?

0.5-2%

Which of the following is a medical consequence of AN?

Amenorrhea

What is the lifetime mortality rate of AN?

5-10%

What is a significant genetic component associated with AN?

Abnormal serotonin metabolism

When does AN typically start?

Adolescence

What are some of the factors that likely contribute to the cause of AN?

Genetic, biological, psychological, social, and cultural factors

What are some common characteristics associated with genetic vulnerabilities in AN?

Perfectionism, inflexibility, and restraint

Which eating disorder is characterized by repeated overeating without compensatory behaviors?

Binge eating disorder

Which eating disorder is linked to abnormal circadian rhythm and potential leptin dysfunction?

Night eating disorder

Which eating disorder is characterized by repeated regurgitation and re-chewing of food, more commonly seen in children?

Rumination disorder

Which eating disorder is similar to anorexia but without fear of weight gain, fat, or body distortions, and is more commonly seen in children?

Avoidant/Restrictive food intake disorder

Which eating disorder is associated with the consumption of non-nutritive substances like paint, plastics, animal droppings, and soil?

Pica

Which eating disorder is characterized by repeated overeating and is estimated to be present in 9-18% of obese individuals, mainly female?

Binge eating disorder

Which eating disorder is characterized by repeated regurgitation and re-chewing of food, more commonly seen in children, especially those with intellectual disabilities?

Rumination disorder

Which biological factor is involved in central appetite regulation?

Hypothalamus

What is the composition of the HPA axis?

Hypothalamus, Pituitary gland, Adrenal gland

What hormone significantly affects appetite regulation due to chronic release?

Corticotrophin Releasing Hormone (CRH)

What is a widely regarded characteristic of Anorexia Nervosa (AN)?

Manifestation of complex rituals

What is the first goal of treatment for AN?

Refeeding

What is the approximate lifetime mortality rate for AN?

5-10%

What factor may contribute to maintaining maladaptive fasting behavior in AN?

Physical addiction to weight loss

What is the prevalence of bulimia nervosa in women?

1-3%

At what age does bulimia nervosa typically develop?

Late adolescence or early adulthood

Which of the following is a medical consequence of bulimia nervosa?

Dental erosion

What are predisposing factors for bulimia nervosa?

History of anorexia nervosa

What physiological changes are related to abnormal satiety in bulimia nervosa?

Enlarged gastric capacity

What percentage of individuals with bulimia nervosa make a full recovery?

50%

What is the usual treatment for bulimia nervosa?

Cognitive-behavioral therapy (CBT) and antidepressants

How does the mortality rate of bulimia nervosa compare to anorexia nervosa?

Lower

Which of the following statements about additional treatments for bulimia nervosa is true?

Certain anti-depressants are only effective after refeeding

Study Notes

Understanding Bulimia Nervosa

  • Bulimia nervosa includes behaviors such as binge eating, recurrent inappropriate compensatory behaviors, and an undue influence on body weight and shape.
  • Prevalence of bulimia nervosa is 1-3% in women, with a predominantly female occurrence, and typically develops in late adolescence or early adulthood.
  • Medical consequences of bulimia nervosa include dental erosion, swelling of the parotid glands, electrolyte abnormalities, and rare complications such as oesophageal tear/gastric rupture.
  • Predisposing factors for bulimia nervosa include a history of anorexia nervosa, childhood and parental obesity, history of dieting, family environment, critical comments about weight during adolescence, and sexual abuse.
  • The instigation of bulimia nervosa may start with dieting, preoccupation with weight, and discovering methods for quick weight loss, which leads to loss of perceived control over eating and purging.
  • The maintenance of bulimia nervosa involves various physiological changes related to abnormal satiety, such as enlarged gastric capacity, delayed gastric emptying, reduced gastric elasticity, impaired CCK release, reduced vagal information flow, abnormal serotonergic function, and serum leptin levels.
  • Prognosis for bulimia nervosa suggests that 50% make a full recovery, 30% experience occasional relapse, and 20% exhibit chronic bulimia nervosa.
  • Treatment for bulimia nervosa usually involves a combination of cognitive-behavioral therapy (CBT) and antidepressants, which have shown to be quite successful, with CBT identifying cues to bingeing and how to deal with them.
  • Bulimia nervosa is relatively more amenable to treatment than anorexia nervosa and has a lower mortality rate.
  • Bulimia nervosa has complex causation, still not fully understood, and it is crucial to recognize the differences between anorexia nervosa and bulimia nervosa.
  • Additional treatments for bulimia nervosa include certain anti-depressants, which are only effective after refeeding and may assist in preventing relapse.
  • BN is far more easily treated than AN and has one of the highest mortality rates of any psychiatric condition.

Test your knowledge on bulimia nervosa with this informative quiz covering its prevalence, medical consequences, predisposing factors, instigation, maintenance, prognosis, and treatment options. Gain a better understanding of this complex eating disorder and learn to differentiate it from anorexia nervosa.

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