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Questions and Answers
What happens to a buffer solution when a strong base is added?
What happens to a buffer solution when a strong base is added?
What happens to a buffer solution when a strong acid is added?
What happens to a buffer solution when a strong acid is added?
What does acetate (CH3COO-) do when strong base (OH-) is added to a buffer solution?
What does acetate (CH3COO-) do when strong base (OH-) is added to a buffer solution?
What is the molar ratio, [Salt]/[Acid], required to prepare an acetate buffer of pH 5.0?
What is the molar ratio, [Salt]/[Acid], required to prepare an acetate buffer of pH 5.0?
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What is the pH of a solution containing 0.10 mole of ephedrine and 0.01 mole of ephedrine hydrochloride per liter of solution?
What is the pH of a solution containing 0.10 mole of ephedrine and 0.01 mole of ephedrine hydrochloride per liter of solution?
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Study Notes
Buffers
- A buffer is a compound or mixture of compounds that resists changes in pH when small amounts of strong acid or base are added to a solution.
- Buffers can be a combination of a weak acid and its conjugate base (e.g., HAc and NaAc) or a weak base and its conjugate acid (e.g., Ephedrine and Ephedrine HCl or NH3 and NH4Cl).
Buffer Action
- Buffer action is the resistance of a buffer to changes in pH.
- When a small amount of strong acid or base is added to water or a solution of sodium chloride, the pH changes significantly, demonstrating a lack of buffer action.
Buffer Capacity (β)
- Buffer capacity (β) measures the magnitude of a buffer's resistance to pH changes.
- High buffer capacity is necessary to maintain a constant pH, such as in blood, which is maintained at pH 7.4.
Importance of Buffers
- Buffers are frequently used in pharmaceutical practice to hold the pH constant, particularly in ophthalmic and I.V. injections.
- The ability of a buffer to resist changes in pH is crucial in these applications.
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Description
Test your knowledge of buffer solutions with this quiz. Learn about the compounds that resist changes in pH and their importance in maintaining stable pH levels in solutions.