Bronchopulmonary Dysplasia (BPD)

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Questions and Answers

Bronchopulmonary Dysplasia (BPD) primarily results in which of the following pulmonary changes?

  • Decreased surfactant production and alveolar collapse
  • Impaired alveolar development and fibrosis (correct)
  • Increased alveolar development and reduced fibrosis
  • Increased lung compliance and decreased airway resistance

Oxygen therapy and mechanical ventilation in preterm infants can be causative factors in the development of Bronchopulmonary Dysplasia (BPD).

True (A)

What is the primary population at risk for developing Bronchopulmonary Dysplasia (BPD)?

Preterm infants

One of the primary characteristics of Bronchopulmonary Dysplasia (BPD) is the presence of lung ______.

<p>fibrosis</p> Signup and view all the answers

Match the following factors with their impact on the risk of developing Bronchopulmonary Dysplasia (BPD):

<p>Prematurity = Increases risk Advanced gestational age = Decreases risk Mechanical Ventilation = Increases risk Adequate surfactant production = Decreases risk</p> Signup and view all the answers

Which intervention is most directly linked to the pathological changes observed in Bronchopulmonary Dysplasia (BPD)?

<p>Prolonged mechanical ventilation (B)</p> Signup and view all the answers

Bronchopulmonary Dysplasia (BPD) is primarily a congenital condition present at birth.

<p>False (B)</p> Signup and view all the answers

Besides mechanical ventilation and oxygen therapy, name another factor that could potentially increase the severity of BPD.

<p>Prematurity</p> Signup and view all the answers

Impaired ______ development is a key component in the pathophysiology of Bronchopulmonary Dysplasia (BPD).

<p>alveolar</p> Signup and view all the answers

Match each characteristic with its relevance to Bronchopulmonary Dysplasia (BPD):

<p>Fibrosis = Lung scarring Alveolar simplification = Decreased gas exchange Inflammation = Airway injury Hyperoxia = Oxidative stress</p> Signup and view all the answers

The underlying mechanism in Bronchopulmonary Dysplasia (BPD) primarily involves what?

<p>Inadequate formation of new alveoli (D)</p> Signup and view all the answers

Administering high concentrations of oxygen to preterm infants always prevents the development of Bronchopulmonary Dysplasia (BPD).

<p>False (B)</p> Signup and view all the answers

Name a chronic pulmonary change, other than fibrosis, observed in infants with Bronchopulmonary Dysplasia (BPD).

<p>impaired alveolar development</p> Signup and view all the answers

In Bronchopulmonary Dysplasia (BPD), the use of mechanical ______ can lead to lung injury over time.

<p>ventilation</p> Signup and view all the answers

Match the risk factor with its contribution to the development of Bronchopulmonary Dysplasia (BPD):

<p>Prematurity = Immature lung structure Oxygen toxicity = Free radical damage to lung tissue Barotrauma = Physical damage from mechanical ventilation Inflammation = Exacerbates lung injury</p> Signup and view all the answers

Which of the following most accurately describes the long-term respiratory consequence in infants who survive Bronchopulmonary Dysplasia (BPD)?

<p>Increased risk of respiratory infections and long-term respiratory problems (A)</p> Signup and view all the answers

Infants born at term are at a higher risk of developing Bronchopulmonary Dysplasia (BPD) compared to preterm infants.

<p>False (B)</p> Signup and view all the answers

What cellular process contributes to the structural changes seen in Bronchopulmonary Dysplasia (BPD)?

<p>fibrosis</p> Signup and view all the answers

Besides prematurity, prolonged exposure to high concentrations of ______ is a risk factor for Bronchopulmonary Dysplasia (BPD).

<p>oxygen</p> Signup and view all the answers

Relate each intervention to its role in the potential development or prevention of Bronchopulmonary Dysplasia (BPD):

<p>Mechanical ventilation = Can cause lung injury CPAP = May reduce the need for ventilation Oxygen therapy = Can cause oxidative stress Surfactant administration = Helps alveolar stability</p> Signup and view all the answers

Why does prematurity significantly increase the risk of developing Bronchopulmonary Dysplasia (BPD)?

<p>Due to incomplete alveolar and vascular development in the lungs. (C)</p> Signup and view all the answers

The use of mechanical ventilation is always avoidable in preterm infants at risk for Bronchopulmonary Dysplasia (BPD).

<p>False (B)</p> Signup and view all the answers

Besides oxygen toxicity and barotrauma, what is another mechanism by which mechanical ventilation can contribute to the development of BPD?

<p>Inflammation</p> Signup and view all the answers

In Bronchopulmonary Dysplasia, damage from mechanical ventilation and oxygen therapy can lead to ______ of the lung tissues.

<p>inflammation</p> Signup and view all the answers

Match each term with the physiological process it relates to in Bronchopulmonary Dysplasia:

<p>Alveolar simplification = Reduced gas exchange Pulmonary fibrosis = Increased stiffness Hyperoxia = Free radical formation Mechanical ventilation = Barotrauma or volutrauma</p> Signup and view all the answers

What is the primary consequence of the fibrotic changes observed in the lungs of infants with Bronchopulmonary Dysplasia (BPD)?

<p>Reduced gas exchange efficiency and impaired respiratory function (C)</p> Signup and view all the answers

Bronchopulmonary Dysplasia (BPD) typically resolves completely within the first year of life without any long-term respiratory consequences.

<p>False (B)</p> Signup and view all the answers

What structural component of the lung is most affected in Bronchopulmonary Dysplasia (BPD)?

<p>Alveoli</p> Signup and view all the answers

The use of sustained high concentrations of inspired ______ can result in oxidative damage to premature lung tissue, increasing the risk of BPD.

<p>oxygen</p> Signup and view all the answers

Match the following interventions in neonatal care with their potential impact on the development of Bronchopulmonary Dysplasia (BPD):

<p>Gentle ventilation strategies = Reduces risk of lung injury Judicious fluid management = Prevents pulmonary edema Early nutritional support = Supports lung development Corticosteroid use (in specific cases) = Reduces inflammation</p> Signup and view all the answers

Which of the following factors has the LEAST influence on the development of Bronchopulmonary Dysplasia (BPD) in premature infants?

<p>Maternal diet during pregnancy (B)</p> Signup and view all the answers

If preterm infants require mechanical ventilation, higher tidal volumes reduce the incidence of BPD.

<p>False (B)</p> Signup and view all the answers

Aside from mechanical ventilation, name a noninvasive ventilation strategy that may reduce risk of BPD in some cases.

<p>CPAP</p> Signup and view all the answers

The process of ______ leads to less elastic tissue within the lungs of infants with BPD, reducing lung function.

<p>fibrosis</p> Signup and view all the answers

Match the following terms with their mechanism of injury in Bronchopulmonary Dysplasia:

<p>High FiO2 = Free radical mediated injury Positive Pressure Ventilation = Volutrauma / Barotrauma Inflammation = Release of cytokines and proteases PDA Ligation = Pulmonary edema</p> Signup and view all the answers

Which of the following is the MOST appropriate strategy to protect preterm infants from developing BPD?

<p>Minimizing exposure to mechanical ventilation whenever possible (D)</p> Signup and view all the answers

Increased inspired oxygen is always the main cause in BPD.

<p>False (B)</p> Signup and view all the answers

Beyond mechanical ventilation and oxygen exposure, what is another risk factor of BPD?

<p>premature birth</p> Signup and view all the answers

BPD usually develops due to lung ______.

<p>damage</p> Signup and view all the answers

Match the following potential mechanical ventilation parameters to lung protective strategies:

<p>Peak Inspiratory Pressure = Lowest pressure to produce adequate chest rise Tidal Volume = Minimize overdistention and maintain permissable hypercapnea FiO2 = Lowest amount to meet SpO2 goal PEEP = Avoid atelectasis with appropriate levels</p> Signup and view all the answers

Flashcards

Bronchopulmonary Dysplasia (BPD)

Chronic lung disease in preterm infants caused by oxygen therapy and mechanical ventilation, leading to impaired alveolar development and fibrosis.

Prematurity (BPD)

A major risk factor for Bronchopulmonary Dysplasia (BPD).

Study Notes

  • Bronchopulmonary Dysplasia (BPD) is also known as chronic lung disease of prematurity.
  • BPD is a chronic lung disease in preterm infants.
  • BPD is caused by oxygen therapy and mechanical ventilation.
  • BPD leads to impaired alveolar development and fibrosis.

Risk Factors

  • Prematurity is a risk factor.

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