30 Questions
What is the first-line maintenance therapy for controlling asthma in patients with chronic asthma?
Inhaler steroids
Which of the following is a known side effect of glucocorticoids?
Osteoporosis
What should patients do after each use of inhaler therapy to avoid oropharyngeal candidiasis?
Gargle with warm water or antiseptic
What is the recommended approach when switching patients from oral to inhaled steroid therapy?
Taper oral therapy gradually
Which alternative therapy is NOT recommended for the treatment of asthma due to weak anti-inflammatory effects and short duration of action?
Cromolyn
What precautions should be taken after prolonged use of systemic steroids to prevent adreno-cortical insufficiency?
Gradually taper off the steroids
What is the primary mechanism of action of β2-Adrenoceptor agonists in treating asthma?
Direct stimulant action on β2 adrenoceptors of bronchial smooth muscle
When are short-acting bronchodilators like Salbutamol typically used?
For quick relief during acute asthma attacks
Which of the following is a side effect associated with bronchodilators like Salmeterol and Formoterol?
Hypokalemia
What is a potential consequence of regular use of bronchodilators according to the text?
Bronchial hyperreactivity and failure in response
Which type of agents are Salmeterol and Formoterol classified as?
Long-acting agents
What is the main purpose of using short-acting bronchodilators like Albuterol according to the text?
Quick relief during acute wheezing episodes
What is the mechanism of action of a mast cell stabilizer like cromolyn?
Preventing histamine release from mast cells
Which medication is useful for reducing the symptoms of allergic rhinitis?
Omalizumab
What is the primary adverse effect associated with zileuton?
Elevations in serum hepatic enzymes
What is the role of leukotriene receptor antagonists like zafirlukast and montelukast in asthma treatment?
Blocking the cysteinyl LT-1 receptor
What is the function of omalizumab in allergic asthma therapy?
Preventing activation by asthma triggers
How do leukotriene modulators like zafirlukast and zileuton differ in their mechanism of action?
Zafirlukast inhibits 5-lipoxygenase while zileuton blocks the cysteinyl LT-1 receptor
Which enzyme do xanthines like Theophylline inhibit?
Phosphodiesterase
What is a potential fatal side effect of administering Theophylline through IV?
Dysrhythmia
When should oral preparations of Theophylline be given?
With meals
What is a precaution when administering Theophylline with sympathomimetics?
Avoid non-selective β-agonists
How is Ipratropium bromide administered?
As aerosol inhalation
What is the mechanism of action of Muscarinic receptor antagonists like Tiotropium?
Blocking M3 receptors on smooth muscle
Which phase of asthma does the mentioned drug have no effect on?
Late inflammatory phase
What is one of the disadvantages of the mentioned drug mentioned in the text?
Delayed onset of action
Which type of drugs are glucocorticoids primarily known as?
Anti-inflammatory drugs
What is the main therapy for moderate, severe, acute, and chronic asthma according to the text?
Glucocorticoids
In status asthmaticus, what is the recommended initial glucocorticoid for IV administration?
Hydrocortisone
What is the mechanism of action of glucocorticoids in asthma treatment?
Inhibition of T-cell activation and inflammatory response
This quiz focuses on a bronchodilator that inhibits the increase of mucus secretion in asthma and may increase the clearance of bronchial secretions. It discusses the advantages and disadvantages of this bronchodilator, highlighting its effects in asthma treatment.
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