Bronchodilator Inhibiting Mucus Secretion in Asthma
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Questions and Answers

What is the first-line maintenance therapy for controlling asthma in patients with chronic asthma?

  • Leukotriene modulators
  • Mast cell stabilizers
  • Oral prednisone
  • Inhaler steroids (correct)

Which of the following is a known side effect of glucocorticoids?

  • Osteoporosis (correct)
  • Headache
  • Joint pain
  • Nausea and vomiting

What should patients do after each use of inhaler therapy to avoid oropharyngeal candidiasis?

  • Use a cough syrup
  • Take an antacid
  • Gargle with warm water or antiseptic (correct)
  • Drink a cold beverage

What is the recommended approach when switching patients from oral to inhaled steroid therapy?

<p>Taper oral therapy gradually (D)</p> Signup and view all the answers

Which alternative therapy is NOT recommended for the treatment of asthma due to weak anti-inflammatory effects and short duration of action?

<p>Cromolyn (B)</p> Signup and view all the answers

What precautions should be taken after prolonged use of systemic steroids to prevent adreno-cortical insufficiency?

<p>Gradually taper off the steroids (A)</p> Signup and view all the answers

What is the primary mechanism of action of β2-Adrenoceptor agonists in treating asthma?

<p>Direct stimulant action on β2 adrenoceptors of bronchial smooth muscle (A)</p> Signup and view all the answers

When are short-acting bronchodilators like Salbutamol typically used?

<p>For quick relief during acute asthma attacks (B)</p> Signup and view all the answers

Which of the following is a side effect associated with bronchodilators like Salmeterol and Formoterol?

<p>Hypokalemia (C)</p> Signup and view all the answers

What is a potential consequence of regular use of bronchodilators according to the text?

<p>Bronchial hyperreactivity and failure in response (B)</p> Signup and view all the answers

Which type of agents are Salmeterol and Formoterol classified as?

<p>Long-acting agents (C)</p> Signup and view all the answers

What is the main purpose of using short-acting bronchodilators like Albuterol according to the text?

<p>Quick relief during acute wheezing episodes (C)</p> Signup and view all the answers

What is the mechanism of action of a mast cell stabilizer like cromolyn?

<p>Preventing histamine release from mast cells (D)</p> Signup and view all the answers

Which medication is useful for reducing the symptoms of allergic rhinitis?

<p>Omalizumab (A)</p> Signup and view all the answers

What is the primary adverse effect associated with zileuton?

<p>Elevations in serum hepatic enzymes (C)</p> Signup and view all the answers

What is the role of leukotriene receptor antagonists like zafirlukast and montelukast in asthma treatment?

<p>Blocking the cysteinyl LT-1 receptor (C)</p> Signup and view all the answers

What is the function of omalizumab in allergic asthma therapy?

<p>Preventing activation by asthma triggers (B)</p> Signup and view all the answers

How do leukotriene modulators like zafirlukast and zileuton differ in their mechanism of action?

<p>Zafirlukast inhibits 5-lipoxygenase while zileuton blocks the cysteinyl LT-1 receptor (B)</p> Signup and view all the answers

Which enzyme do xanthines like Theophylline inhibit?

<p>Phosphodiesterase (B)</p> Signup and view all the answers

What is a potential fatal side effect of administering Theophylline through IV?

<p>Dysrhythmia (B)</p> Signup and view all the answers

When should oral preparations of Theophylline be given?

<p>With meals (C)</p> Signup and view all the answers

What is a precaution when administering Theophylline with sympathomimetics?

<p>Avoid non-selective β-agonists (A)</p> Signup and view all the answers

How is Ipratropium bromide administered?

<p>As aerosol inhalation (A)</p> Signup and view all the answers

What is the mechanism of action of Muscarinic receptor antagonists like Tiotropium?

<p>Blocking M3 receptors on smooth muscle (D)</p> Signup and view all the answers

Which phase of asthma does the mentioned drug have no effect on?

<p>Late inflammatory phase (A)</p> Signup and view all the answers

What is one of the disadvantages of the mentioned drug mentioned in the text?

<p>Delayed onset of action (D)</p> Signup and view all the answers

Which type of drugs are glucocorticoids primarily known as?

<p>Anti-inflammatory drugs (D)</p> Signup and view all the answers

What is the main therapy for moderate, severe, acute, and chronic asthma according to the text?

<p>Glucocorticoids (B)</p> Signup and view all the answers

In status asthmaticus, what is the recommended initial glucocorticoid for IV administration?

<p>Hydrocortisone (A)</p> Signup and view all the answers

What is the mechanism of action of glucocorticoids in asthma treatment?

<p>Inhibition of T-cell activation and inflammatory response (A)</p> Signup and view all the answers

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