Brain Anatomy and Functions

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Questions and Answers

What is the standard initial treatment for stroke?

  • Intravenous fluids
  • Oral aspirin (correct)
  • Surgical intervention
  • Heparin injection

Which modifiable risk factor is associated with stroke prevention?

  • Hypertension (correct)
  • Gender
  • Age
  • Genetics

What is a clinical stroke primarily characterized by?

  • Symptoms occurring only during sleep
  • Rapid onset of symptoms lasting more than 24 hours (correct)
  • Symptoms associated with infection
  • Gradual onset of symptoms

Which treatment reduces the risk of further ischaemic strokes but increases the risk of brain hemorrhage?

<p>Heparin (B)</p> Signup and view all the answers

Which of the following is a condition that may mimic the symptoms of a stroke?

<p>Epileptic seizure (C)</p> Signup and view all the answers

What is the lifetime risk of experiencing a stroke for men?

<p>1 in 4 (C)</p> Signup and view all the answers

Which lifestyle change is recommended for those with hypertension to lower stroke risk?

<p>Regular physical activity (B)</p> Signup and view all the answers

What effect do statins have in relation to stroke risk?

<p>Reduce cholesterol levels (D)</p> Signup and view all the answers

What is the primary factor that leads to a stroke or transient ischaemic attack (TIA)?

<p>Interruption of blood supply to the brain (A)</p> Signup and view all the answers

Which of the following is true regarding the resolution of TIAs?

<p>90% of TIAs resolve within 90 minutes. (A)</p> Signup and view all the answers

Which brain function is primarily controlled by the motor cortex?

<p>Movement (C)</p> Signup and view all the answers

What is a characteristic feature of the brain's structure in relation to body representation?

<p>Certain body parts, like the face and hands, are overrepresented. (A)</p> Signup and view all the answers

What percentage of the body's total energy does the brain use?

<p>20% (A)</p> Signup and view all the answers

Which of the following factors does NOT increase the risk of stroke?

<p>Regular exercise (A)</p> Signup and view all the answers

The cerebral cortex is responsible for which of the following functions?

<p>Processing sensations like touch and sight (B)</p> Signup and view all the answers

What is a common feature of a randomised, double-blind, placebo-controlled study?

<p>Both participants and researchers are unaware of who receives treatment or placebo. (A)</p> Signup and view all the answers

What is the primary cause of strokes in the majority of cases?

<p>Infarction (D)</p> Signup and view all the answers

Which layer of the meninges is the outermost and toughest?

<p>Dura mater (C)</p> Signup and view all the answers

What is a common treatment option for managing increased cholesterol in stroke patients?

<p>Statins (D)</p> Signup and view all the answers

Which condition represents a smaller percentage of stroke causes than atherothromboembolism?

<p>Rarities (C)</p> Signup and view all the answers

What is essential for deciding the treatment approach for a stroke?

<p>Understanding brain anatomy (D)</p> Signup and view all the answers

Which structural feature primarily protects the brain and spinal cord?

<p>Meninges (D)</p> Signup and view all the answers

What percentage of strokes are attributable to haemorrhage?

<p>15% (D)</p> Signup and view all the answers

Which treatment method might be considered for patients with carotid stenosis?

<p>Carotid surgery (C)</p> Signup and view all the answers

Which structure is NOT part of the corpus striatum?

<p>Postcentral gyrus (C)</p> Signup and view all the answers

What is the primary function of the precentral gyrus?

<p>Executing voluntary motor functions (A)</p> Signup and view all the answers

Which area is primarily responsible for processing auditory information?

<p>Transverse gyrus of the temporal lobe (C)</p> Signup and view all the answers

What type of sensory information does the somatic sensory area primarily process?

<p>Touch and temperature (B)</p> Signup and view all the answers

Which of the following structures receives sensory impulses from receptors activated by heat, cold, and touch?

<p>Postcentral gyrus (D)</p> Signup and view all the answers

What term describes the brain's ability to adapt and reorganise its functions in response to experience or injury?

<p>Cerebral plasticity (C)</p> Signup and view all the answers

What is the primary role of the falx cerebri?

<p>To partition the two cerebral hemispheres (B)</p> Signup and view all the answers

How is sensory information from the body mapped in the brain?

<p>Proportionally based on sensory receptor density (D)</p> Signup and view all the answers

Which of the following best describes the location of the dura mater?

<p>It lines the inner roof of the cranium and extends to the spinal nerve roots. (A)</p> Signup and view all the answers

What is the function of the choroid plexuses?

<p>They produce cerebrospinal fluid. (A)</p> Signup and view all the answers

Which function is NOT attributed to the basal nuclei?

<p>Processing auditory information (A)</p> Signup and view all the answers

Which structure is responsible for reabsorbing cerebrospinal fluid into the blood?

<p>Arachnoid villus (D)</p> Signup and view all the answers

What separates the two hemispheres of the cerebellum?

<p>Falx cerebelli (D)</p> Signup and view all the answers

Cerebrospinal fluid flows through several structures; which of the following is the correct sequence starting from the lateral ventricles?

<p>Lateral ventricles, interventricular foramen, third ventricle, cerebral aqueduct, fourth ventricle (A)</p> Signup and view all the answers

Which space lies just below the dura mater?

<p>Subdural space (B)</p> Signup and view all the answers

What is NOT a space between the meninges?

<p>Arachnoid space (D)</p> Signup and view all the answers

Which structure is primarily responsible for integration of basic vital functions?

<p>Medulla oblongata (D)</p> Signup and view all the answers

What is the primary function of the thalamus?

<p>Processing of sensory information (B)</p> Signup and view all the answers

Which structure is involved in the subconscious integration of basic reflexes?

<p>Spinal cord (A)</p> Signup and view all the answers

Which part of the brain is primarily involved in higher-level processing of sensory and motor information?

<p>Cerebral cortex (C)</p> Signup and view all the answers

What is the main role of the basal nuclei?

<p>Coordination of voluntary movements (B)</p> Signup and view all the answers

What does the reticular formation primarily regulate?

<p>State of consciousness (C)</p> Signup and view all the answers

Which of the following reflexes is NOT primarily integrated by the midbrain?

<p>Digestion reflexes (C)</p> Signup and view all the answers

What is the main function of the hypothalamus in the limbic system?

<p>Controlling thirst and appetite (D)</p> Signup and view all the answers

Which structure connects the left and right hemispheres of the cerebrum?

<p>Corpus callosum (D)</p> Signup and view all the answers

What does short-term memory involve?

<p>Retrieving information lasting a few seconds or minutes (D)</p> Signup and view all the answers

How do aspirin and heparin function in the context of stroke treatment?

<p>Aspirin reduces platelet stickiness; heparin thins the blood (A)</p> Signup and view all the answers

Which of the following is NOT a symptom of a posterior circulation stroke?

<p>Dysphagia (B)</p> Signup and view all the answers

Which component of the nervous system is primarily involved in processing emotional responses?

<p>Limbic system (A)</p> Signup and view all the answers

Flashcards

Dura Mater

The outermost layer of the meninges, a three-layered protective membrane covering the brain and spinal cord.

Falx Cerebri

A fold of dura mater that separates the two cerebral hemispheres in the longitudinal fissure.

Falx Cerebelli

A fold of dura mater that separates the two cerebellar hemispheres.

Tentorium Cerebelli

A fold of dura mater that separates the cerebellum from the cerebrum.

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Epidural Space

The space between the dura mater and the skull.

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Subdural Space

The space between the dura mater and the arachnoid mater.

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Subarachnoid Space

The space between the arachnoid mater and the pia mater, where cerebrospinal fluid (CSF) circulates.

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Choroid Plexuses

Networks of capillaries that produce cerebrospinal fluid (CSF).

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Cerebrospinal Fluid (CSF)

Fluid that cushions and protects the brain and spinal cord.

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Stroke

Interruption of blood supply to the brain, causing damage to brain tissue.

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Brain Blood Supply

Essential for delivering oxygen and nutrients to brain cells.

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Anterior Circulation

Part of the brain's blood supply, supplying the front part of the brain.

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Posterior Circulation

Part of the brain's blood supply, supplying the back part of the brain.

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Cerebral Cortex

Outermost layer of the brain, responsible for higher-level functions.

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Motor Functions (brain)

Brain functions related to movement.

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Sensory Functions (brain)

Brain functions related to sensation (touch, sight, sound, etc).

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Language Functions (brain)

Brain functions responsible for language.

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TIA

Transient Ischemic Attack - temporary disruption of blood flow to the brain.

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Stroke Risk Factors

Conditions increasing the chance of a stroke (e.g., age, high blood pressure).

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Initial Stroke Investigation

Procedures done to understand the cause and location of a stroke.

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Initial Stroke Treatment

Initial actions taken to address an acute stroke.

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Parkinson's Disease

Progressive neurological disorder affecting movement.

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Stroke

A rapid-onset focal neurological event lasting more than 24 hours (or leading to death), with no apparent cause other than vascular issues.

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Modifiable Stroke Risk Factor

Health factors that can be changed to reduce stroke risk, e.g., hypertension, smoking, and high cholesterol

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Hypertension

High blood pressure, a major risk factor for stroke.

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Smoking

Harmful habit increasing stroke risk.

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Hyperlipidaemia

High levels of lipids (fats) in the blood raising stroke risk.

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Diabetes Mellitus

A metabolic disorder increasing stroke risk.

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Aspirin

Reduces platelet stickiness, used to prevent further ischaemic strokes.

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Heparin

Thins blood to treat clots to prevent further stroke. But has a risk of causing brain hemorrhage,.

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Clinical Stroke Symptoms

Rapid-onset, focal neurological signs or symptoms lasting longer than 24 hours.

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Stroke Treatment

Treatment options after a stroke include aspirin, blood pressure control, statins, stroke unit care, carotid surgery, and anticoagulation.

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Stroke Causes: Infarction

Infarction (85% of strokes) is caused by blocked blood flow, stemming from issues like atherosclerosis (50%), small vessel disease (25%), heart emboli (20%), and less common factors (5%).

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Stroke Causes: Haemorrhage

Haemorrhage (15% of strokes) is caused by bleeding in the brain.

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Stroke Treatment Decision

Stroke treatment decisions depend on understanding brain anatomy, underlying causes (pathogenesis), and how best to adjust care to the individual.

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Brain Coverings: Meninges

The brain and spinal cord are protected by three layers of membranes called meninges.

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Dura Mater

The toughest, outermost layer of the meninges, providing crucial protection.

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Arachnoid Mater

The middle, web-like layer of the meninges; it is thinner than the dura mater.

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Pia Mater

The innermost, delicate layer of the meninges, adhering tightly to the brain.

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Basal Nuclei Function

Regulates voluntary movements, thought, and learning.

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Cerebral Plasticity

Brain's ability to adapt its functions in response to injury, experience, or change.

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Postcentral Gyrus

Main sensory area for touch, heat, and cold.

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Precentral Gyrus

Main motor area that sends signals to muscles.

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Primary Auditory Area

In temporal lobe; processes sound.

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Primary Visual Area

Located in the occipital lobe; processes sight.

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Somatic Senses

Sensations of touch, pressure, temperature, and body position.

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Special Senses

Vision, hearing, and other perceptions needing complex organs.

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Primary Sensory Areas Relay

Sensory info is passed to sensory association areas and other brain parts for evaluation.

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Sensory Receptor Mapping

Sensory areas (like face or hand) have more receptors, leading to larger brain map sections.

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Limbic System Function

Part of the brain involved in processing emotions.

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Short-Term Memory

Storing information for a few seconds or minutes.

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Spinal Cord Function

Connects brain to body. Conducts reflexes and impulses.

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Grey Matter Function

Processes reflexes and filters information.

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White Matter Function

Carries sensory and motor information.

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Brainstem Function

Integrates basic vital functions like breathing and heart rate.

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Medulla Oblongata Function

Controls vital reflexes like breathing and blood pressure

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Pons Function

Controls autonomic functions like respiration

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Midbrain Function

Controls cranial nerve reflexes, e.g. eye movement, sound reflex.

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Reticular Formation Function

Regulates consciousness and alertness.

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Cerebellum Function

Coordinates movement, balance, and posture.

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Diencephalon Function

Processes sensory information and controls autonomic functions.

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Thalamus Function

Relays sensory information to the cerebral cortex.

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Hypothalamus Function

Regulates hormones and certain body functions.

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Pineal Gland Function

Produces melatonin, involved in biological rhythms.

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Cerebrum Function

Highest level of brain function for processing information.

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Cerebral Cortex Function

Processes sensory and motor information, including conscious control.

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Cerebral Tracts Function

Connects different parts of the brain for communication.

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Basal Nuclei Function

Controls automatic movements and posture

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Study Notes

Learning Outcomes

  • Describe the blood supply of the brain
  • Differentiate between anterior and posterior circulations
  • Describe the structure of the cerebral cortex
  • Understand sensory and motor functions of the cerebral cortex
  • Explain language functions of the cerebral cortex
  • Describe pathways in the spinal cord for motor and sensory functions
  • Recognize Parkinson's disease features
  • Recognize the presentation of a stroke and TIA
  • List risk factors for a stroke
  • Outline initial stroke investigation
  • Describe key features of a randomized, double-blind, placebo-controlled study
  • Outline initial treatment for an acute stroke

The Brain

  • Uses 20% of the total energy expenditure
  • Independent of how hard you think
  • Blood supply is vital for delivering oxygen and nutrients
  • Needs sleep
  • Contains 86 billion neurons with a quadrillion synapses (1 followed by 15 zeros)
  • Essential for movement and balance

Brain Anatomy (Page 2)

  • Sensory cortex processes information from the senses
  • Motor cortex controls movements
  • Specific areas of the cortex are dedicated to different functions (hearing, vision, touch, speech, language, emotions, breathing, circulation, appetite, thirst, dreams, ideas)
  • Different parts of the body have different levels of representation in the brain (face & hands are overrepresented)

Motor and Sensory Pathways (Page 3)

  •  Neurons cross over in the medulla (brain stem), controlling opposite sides of the body.
  •  Illustrates the pathways between the brain, spinal cord.

Stroke and TIA (Page 3, 4)

  • Stroke and TIA are caused by interruption of blood supply to the brain.
  •  TIA usually lasts 90 minutes but can be temporary.
  •  Risk increases with age, more common for men.

Types of Stroke (Page 5)

  • Divided based on circulation patterns (anterior and posterior)
  • Anterior circulation: Carotid arteries, Anterior cerebral, Middle cerebral arteries.
  • Posterior circulation: Basilar and Vertebral arteries.

Treatment of Stroke (Page 6)

  •  Aspirin beneficial for heart attacks, reduces platelet stickiness.
  •  Heparin thins blood for clotting in veins; benefit in strokes is unclear.
  • Treatment of choice is oral aspirin.
  •  Lifetime risk 1 in 4 men, 1 in 5 women.

Conditions Mimicking Stroke (Page 7)

  • Brain tumors, Brain abscesses
  • Bleeding around the brain
  • Hypoglycemia (low blood sugar)
  • Neurological conditions (multiple sclerosis, epilepsy)
  • Epileptic seizures

Modifiable Risk Factors for Stroke (Page 7)

  • Hypertension (high blood pressure)
  • Smoking
  • Hyperlipidemia (high blood fat)
  • Diabetes mellitus (high blood sugar)
  • Excessive alcohol use
  • Atrial fibrillation (irregular heart rhythm)

Arteries Supplying the Brain (Pages 27-28)

  •  Detailed diagram displays circulatory routes to the brain
  • Anterior and Posterior Circulation branches.

Anterior/Posterior Circulation Strokes (Page 29)

  • Anterior: loss of movement and/or sensory function affecting face.
  • Posterior: Facial weakness, eye movement problems, coordination loss.

Treatment of Stroke (Page 30)

  • Aspirin: reduces platelet stickiness.
  • Heparin: thins blood, treats clots in veins.
  • Oral aspirin is the standard treatment.

Brain and Spinal Cord Coverings (Pages 8, 9, 12)

  • The outer layer is the dura mater.
  •  Inner layer, Pia mater.
  • Middle layer, Arachnoid mater.
  •   Meninges protect brain and spinal cord.

Central Nervous System (CNS) - Brain and Spinal Cord (Pages 10, 13, 20)

  •  Details of anatomy parts and locations.
  • Illustrates cerebrospinal fluid (CSF) and formation.

Cerebral Cortex, White Matter, Association Fibers (Pages 14, 15, 16, 17)

  •  Grey matter (outside) and white matter (inside).
  •  Different types of tract fibers (projection, association, commissural) connecting different parts of the brain and other portions of the nervous system.

Basal Nuclei, Structures of the Limbic System (Pages 18, 22)

  •  Brain regions associated with motor control, learning, thinking, memory and emotion.
  • Short-term and long-term memory storage illustrated.

Brainstem Structures (Page 23)

  •  Illustrated overview, key roles relating to basic life functions, and integration of functions.
  •  Details locations, structures and roles of the brainstem structures (Medulla, Pons, Midbrain).

Reticular Formation (Pages 20-21)

  •  Critical in maintaining consciousness.
  •  Plays a role in regulating levels of consciousness, and how the body responds to stimuli and information processing.

Functions Localized to Brain Areas (Pages 19, 24)

  • Precise functions and roles of different brain regions.
  •  Sensory areas receive impulses from specific body parts/ sensory receptors.
  • Visual and auditory processing occur in specific areas in the brain.

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