Podcast
Questions and Answers
Which structure is directly involved in both visual processing AND spatial awareness?
Which structure is directly involved in both visual processing AND spatial awareness?
- Cuneus (correct)
- Cingulate gyrus
- Thalamus
- Uncus
Which of these functions is NOT primarily associated with the right hemisphere?
Which of these functions is NOT primarily associated with the right hemisphere?
- Logical reasoning (correct)
- Facial recognition
- Creativity
- Visual spatial processing
Which brain structure interfaces directly with the thalamus to relay information about touch and pressure from the body?
Which brain structure interfaces directly with the thalamus to relay information about touch and pressure from the body?
- Pre-motor cortex
- Cerebellum
- Somatosensory cortex (correct)
- Primary motor cortex
The Precentral gyri are entirely motor, meaning they are involved in...
The Precentral gyri are entirely motor, meaning they are involved in...
What is the primary function of the corpus callosum?
What is the primary function of the corpus callosum?
Which of the following brain regions plays a crucial role in memory, emotions, and smell?
Which of the following brain regions plays a crucial role in memory, emotions, and smell?
Which of these is NOT a key section of the corpus callosum?
Which of these is NOT a key section of the corpus callosum?
Which two major fissures delineate the cerebrum from other brain structures?
Which two major fissures delineate the cerebrum from other brain structures?
A patient exhibits difficulty producing speech, suggesting damage to which brain area?
A patient exhibits difficulty producing speech, suggesting damage to which brain area?
Which lobe of the brain is primarily responsible for processing auditory information?
Which lobe of the brain is primarily responsible for processing auditory information?
What is the primary function of the thalamus?
What is the primary function of the thalamus?
What is the primary difference between the Pre-motor cortex and the Primary motor cortex?
What is the primary difference between the Pre-motor cortex and the Primary motor cortex?
Which of the following brain structures is NOT located on the inferior aspect of the brain?
Which of the following brain structures is NOT located on the inferior aspect of the brain?
What is the main purpose of the olfactory bulb?
What is the main purpose of the olfactory bulb?
In which lobe of the brain is Wernicke's area primarily located?
In which lobe of the brain is Wernicke's area primarily located?
The central sulcus divides which two lobes of the brain?
The central sulcus divides which two lobes of the brain?
What condition is characterized by bleeding occurring between the dura mater and the arachnoid mater due to a tear in a blood vessel?
What condition is characterized by bleeding occurring between the dura mater and the arachnoid mater due to a tear in a blood vessel?
Which type of stroke occurs when a clot blocks a vessel supplying blood to the brain?
Which type of stroke occurs when a clot blocks a vessel supplying blood to the brain?
What is a common diagnostic procedure used to assess conditions like a stroke by examining the subarachnoid space?
What is a common diagnostic procedure used to assess conditions like a stroke by examining the subarachnoid space?
Which of the following statements accurately describes a subarachnoid hematoma?
Which of the following statements accurately describes a subarachnoid hematoma?
In the context of stroke management, which statement regarding the clinical presentation is true?
In the context of stroke management, which statement regarding the clinical presentation is true?
What symptoms may result from damage to the anterior inferior cerebellar artery?
What symptoms may result from damage to the anterior inferior cerebellar artery?
Which artery is primarily responsible for supplying blood to the largest part of the cerebellum?
Which artery is primarily responsible for supplying blood to the largest part of the cerebellum?
What is a common result of vertebrobasilar artery occlusion?
What is a common result of vertebrobasilar artery occlusion?
What role do the cranial meninges have in protecting the central nervous system?
What role do the cranial meninges have in protecting the central nervous system?
What is true about the superior sagittal sinus?
What is true about the superior sagittal sinus?
What structures drain blood into the internal jugular veins?
What structures drain blood into the internal jugular veins?
Which layer of the cranial meninges is the most superficial?
Which layer of the cranial meninges is the most superficial?
Which type of drainage is facilitated by deep cerebral veins?
Which type of drainage is facilitated by deep cerebral veins?
What is a consequence of damage to the dural sinuses?
What is a consequence of damage to the dural sinuses?
Which artery is considered a common location for strokes?
Which artery is considered a common location for strokes?
What is the primary treatment approach for ischemic strokes?
What is the primary treatment approach for ischemic strokes?
Which artery supplies the lateral aspects of the frontal, temporal, and parietal lobes?
Which artery supplies the lateral aspects of the frontal, temporal, and parietal lobes?
Which symptom is commonly associated with a stroke in the anterior cerebral artery?
Which symptom is commonly associated with a stroke in the anterior cerebral artery?
What is the thinnest portion of the brain's ventricular system?
What is the thinnest portion of the brain's ventricular system?
What common issue can lead to hydrocephalus?
What common issue can lead to hydrocephalus?
Which symptom is associated with a basilar artery stroke?
Which symptom is associated with a basilar artery stroke?
How does CSF flow through the ventricular system?
How does CSF flow through the ventricular system?
In which area of the brain does the third ventricle reside?
In which area of the brain does the third ventricle reside?
What is the primary consequence of an AVM in the brain?
What is the primary consequence of an AVM in the brain?
What occurs during recanalization in the treatment of ischemic stroke?
What occurs during recanalization in the treatment of ischemic stroke?
What does a score of 0 indicate on the NIH Stroke Scale?
What does a score of 0 indicate on the NIH Stroke Scale?
Which imaging method is considered the fastest for diagnosing stroke?
Which imaging method is considered the fastest for diagnosing stroke?
What is a significant risk associated with administering tPA to stroke patients?
What is a significant risk associated with administering tPA to stroke patients?
What condition is indicated when a head CT shows a region of decreased density associated with cerebral ischemia?
What condition is indicated when a head CT shows a region of decreased density associated with cerebral ischemia?
What does the penumbra refer to in the context of ischemic strokes?
What does the penumbra refer to in the context of ischemic strokes?
Which of the following is a primary treatment option for acute ischemic stroke?
Which of the following is a primary treatment option for acute ischemic stroke?
Which score on the NIH Stroke Scale suggests moderate impairment in a stroke patient?
Which score on the NIH Stroke Scale suggests moderate impairment in a stroke patient?
What is a contraindication for administering tPA in a stroke patient?
What is a contraindication for administering tPA in a stroke patient?
Which imaging method is most sensitive to ischemic strokes?
Which imaging method is most sensitive to ischemic strokes?
What is a potential outcome of hemorrhagic conversion following an ischemic stroke?
What is a potential outcome of hemorrhagic conversion following an ischemic stroke?
What should be the first step after assessing vital signs and serum glucose in suspected stroke patients?
What should be the first step after assessing vital signs and serum glucose in suspected stroke patients?
What condition is indicated by sudden weakness or numbness in the face, arm, or leg?
What condition is indicated by sudden weakness or numbness in the face, arm, or leg?
Which of the following best describes TNK (Tenecteplase)?
Which of the following best describes TNK (Tenecteplase)?
What is one limitation of MRI compared to head CT?
What is one limitation of MRI compared to head CT?
Which of the following is NOT a function of the insular lobe?
Which of the following is NOT a function of the insular lobe?
Damage to the occipital lobe can result in various visual disturbances. Which of the following is NOT a common consequence of occipital lobe damage?
Damage to the occipital lobe can result in various visual disturbances. Which of the following is NOT a common consequence of occipital lobe damage?
How does the Circle of Willis contribute to maintaining adequate cerebral perfusion?
How does the Circle of Willis contribute to maintaining adequate cerebral perfusion?
Which of the following is a primary function of the parietal lobe?
Which of the following is a primary function of the parietal lobe?
What is the primary characteristic of apraxia?
What is the primary characteristic of apraxia?
Which of these is NOT part of the Circle of Willis?
Which of these is NOT part of the Circle of Willis?
What is the primary function of the anterior communicating artery in the Circle of Willis?
What is the primary function of the anterior communicating artery in the Circle of Willis?
What is the role of the insular cortex in interoception?
What is the role of the insular cortex in interoception?
Damage to the insular lobe can lead to a range of problems. Which of the following is NOT a typical consequence of insular lobe damage?
Damage to the insular lobe can lead to a range of problems. Which of the following is NOT a typical consequence of insular lobe damage?
What is the primary role of the vertebral arteries in the brain's blood supply?
What is the primary role of the vertebral arteries in the brain's blood supply?
Which of the following statements accurately describes the function of the prefrontal cortex?
Which of the following statements accurately describes the function of the prefrontal cortex?
A patient presents with difficulty understanding spoken language, producing fluent but meaningless sentences. This is likely caused by damage to which brain region?
A patient presents with difficulty understanding spoken language, producing fluent but meaningless sentences. This is likely caused by damage to which brain region?
Which of the following is NOT a function associated with the parietal lobe?
Which of the following is NOT a function associated with the parietal lobe?
What is the primary function of the olfactory bulbs?
What is the primary function of the olfactory bulbs?
Damage to which brain region would likely result in difficulties with speech production and articulation?
Damage to which brain region would likely result in difficulties with speech production and articulation?
Which of the following statements accurately describes the relationship between the cerebral hemispheres and the body?
Which of the following statements accurately describes the relationship between the cerebral hemispheres and the body?
Which of the following brain regions is NOT directly involved in language processing?
Which of the following brain regions is NOT directly involved in language processing?
The term 'contralateral representation' refers to:
The term 'contralateral representation' refers to:
Which of the following lobes is primarily responsible for processing visual information?
Which of the following lobes is primarily responsible for processing visual information?
What is the role of the 'insular cortex'?
What is the role of the 'insular cortex'?
What is the significance of the 'Cortical Homunculus'?
What is the significance of the 'Cortical Homunculus'?
Which of the following statements BEST describes the function of the primary motor cortex?
Which of the following statements BEST describes the function of the primary motor cortex?
Which of the following statements accurately describes the location of Broca's area?
Which of the following statements accurately describes the location of Broca's area?
A patient presents with difficulty initiating and controlling voluntary movements, particularly in the right arm and leg. Damage to which brain region is MOST likely responsible for these symptoms?
A patient presents with difficulty initiating and controlling voluntary movements, particularly in the right arm and leg. Damage to which brain region is MOST likely responsible for these symptoms?
Which of the following statements best explains the difference between Broca's aphasia and Wernicke's aphasia?
Which of the following statements best explains the difference between Broca's aphasia and Wernicke's aphasia?
Which of the following brain regions is MOST closely associated with the processing of information related to touch, temperature, and pain?
Which of the following brain regions is MOST closely associated with the processing of information related to touch, temperature, and pain?
Which of the following statements about the arachnoid mater is incorrect?
Which of the following statements about the arachnoid mater is incorrect?
What is the primary function of dural reflections?
What is the primary function of dural reflections?
Identify the correct order of the meninges from the outermost to the innermost layer.
Identify the correct order of the meninges from the outermost to the innermost layer.
The tentorium cerebelli is a dural reflection that separates which structures?
The tentorium cerebelli is a dural reflection that separates which structures?
Which of the following is not a characteristic of the dura mater?
Which of the following is not a characteristic of the dura mater?
The epidural space is located between which layers?
The epidural space is located between which layers?
What is the primary difference between the dura mater of the brain and the dura mater of the spinal cord?
What is the primary difference between the dura mater of the brain and the dura mater of the spinal cord?
Where is the subarachnoid space located?
Where is the subarachnoid space located?
Which of the following statements about the lumbar cistern is true?
Which of the following statements about the lumbar cistern is true?
What is the primary function of the pia mater?
What is the primary function of the pia mater?
Which of the following is not a characteristic of a meningoma?
Which of the following is not a characteristic of a meningoma?
Which of the following statements about an epidural hematoma is correct?
Which of the following statements about an epidural hematoma is correct?
Which of the following structures is not a dural reflection?
Which of the following structures is not a dural reflection?
What is the primary function of the cerebrospinal fluid (CSF)?
What is the primary function of the cerebrospinal fluid (CSF)?
Which of the following statements about meningitis is incorrect?
Which of the following statements about meningitis is incorrect?
Which of the following is not a space within the cranial meninges?
Which of the following is not a space within the cranial meninges?
What is the primary function of the anterior communicating artery?
What is the primary function of the anterior communicating artery?
Which of these structures is NOT directly supplied by the Circle of Willis?
Which of these structures is NOT directly supplied by the Circle of Willis?
What is the likely consequence of damage to the posterior cerebral artery (PCA)?
What is the likely consequence of damage to the posterior cerebral artery (PCA)?
Which of the following accurately describes the relationship between the Circle of Willis and the anterior circulation?
Which of the following accurately describes the relationship between the Circle of Willis and the anterior circulation?
Which artery directly supplies the medial portions of the frontal lobes and the superior medial parietal lobes?
Which artery directly supplies the medial portions of the frontal lobes and the superior medial parietal lobes?
What is the primary function of the posterior communicating arteries?
What is the primary function of the posterior communicating arteries?
What is the most likely consequence of damage to the middle cerebral artery (MCA)?
What is the most likely consequence of damage to the middle cerebral artery (MCA)?
Which statement BEST describes the role of the Circle of Willis in cerebrovascular events?
Which statement BEST describes the role of the Circle of Willis in cerebrovascular events?
What is the primary function of the superior cerebellar artery?
What is the primary function of the superior cerebellar artery?
Which statement accurately describes the difference between the anterior and posterior cerebral circulation?
Which statement accurately describes the difference between the anterior and posterior cerebral circulation?
What is the significance of the fact that the internal carotid arteries and vertebral arteries course through the neck and base of the skull?
What is the significance of the fact that the internal carotid arteries and vertebral arteries course through the neck and base of the skull?
Which statement BEST describes the role of the Circle of Willis in ensuring comprehensive care within an interdisciplinary team?
Which statement BEST describes the role of the Circle of Willis in ensuring comprehensive care within an interdisciplinary team?
Which brain region is MOST likely to be affected by a blockage in the anterior cerebral artery (ACA)?
Which brain region is MOST likely to be affected by a blockage in the anterior cerebral artery (ACA)?
What is the significance of the anterior cerebral artery being crucial for higher cognitive functions?
What is the significance of the anterior cerebral artery being crucial for higher cognitive functions?
Which statement BEST describes the relationship between the Circle of Willis and the posterior circulation?
Which statement BEST describes the relationship between the Circle of Willis and the posterior circulation?
Which artery is MOST likely to be affected by a cerebral aneurysm?
Which artery is MOST likely to be affected by a cerebral aneurysm?
Flashcards
Auditory Cortex
Auditory Cortex
Part of the temporal lobe that processes sound information.
Broca's Area
Broca's Area
Region critical for speech production and articulation, located in the frontal lobe.
Olfactory Bulbs
Olfactory Bulbs
Forebrain structures that process smell information.
Cortical Homunculus
Cortical Homunculus
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Primary Motor Cortex
Primary Motor Cortex
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Primary Somatosensory Cortex
Primary Somatosensory Cortex
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Contralateral Representation
Contralateral Representation
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Frontal Lobe
Frontal Lobe
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Wernicke’s Area
Wernicke’s Area
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Temporal Lobe
Temporal Lobe
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Parietal Lobe
Parietal Lobe
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Broca’s Aphasia
Broca’s Aphasia
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Wernicke’s Aphasia
Wernicke’s Aphasia
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Insular Cortex
Insular Cortex
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Limbic System
Limbic System
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Cerebrum
Cerebrum
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Cerebral Cortex
Cerebral Cortex
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Left Hemisphere Function
Left Hemisphere Function
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Wernicke's Area
Wernicke's Area
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Right Hemisphere Function
Right Hemisphere Function
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Central Sulcus
Central Sulcus
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Cerebellum
Cerebellum
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Thalamus
Thalamus
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Corpus Callosum
Corpus Callosum
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Somatosensory Cortex
Somatosensory Cortex
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Cingulate Gyrus
Cingulate Gyrus
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Occipital Lobe
Occipital Lobe
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Lateral Sulcus
Lateral Sulcus
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Apraxia
Apraxia
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Functions of the Occipital Lobe
Functions of the Occipital Lobe
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Visual Disturbances
Visual Disturbances
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Insular Lobe
Insular Lobe
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Interoception
Interoception
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Functions of the Insular Lobe
Functions of the Insular Lobe
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Circle of Willis
Circle of Willis
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Main Arterial Components
Main Arterial Components
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Implications of Understanding the Circle of Willis
Implications of Understanding the Circle of Willis
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Internal carotid arteries
Internal carotid arteries
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Vertebral arteries
Vertebral arteries
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Anterior communicating artery
Anterior communicating artery
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Middle Cerebral Artery (MCA)
Middle Cerebral Artery (MCA)
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Anterior cerebral artery (ACA)
Anterior cerebral artery (ACA)
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Posterior cerebral artery (PCA)
Posterior cerebral artery (PCA)
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Contralateral hemiplegia
Contralateral hemiplegia
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Cerebellar ataxia
Cerebellar ataxia
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Aneurysms
Aneurysms
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Subarachnoid space
Subarachnoid space
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Homonymous hemianopsia
Homonymous hemianopsia
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Basilar artery
Basilar artery
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Cerebral circulation
Cerebral circulation
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Anterior Inferior Cerebellar Artery
Anterior Inferior Cerebellar Artery
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Symptoms of Anterior Inferior Cerebellar Artery Damage
Symptoms of Anterior Inferior Cerebellar Artery Damage
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Posterior Inferior Cerebellar Artery
Posterior Inferior Cerebellar Artery
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Symptoms of PICA Damage
Symptoms of PICA Damage
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Vertebrobasilar Arteries
Vertebrobasilar Arteries
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Symptoms of Vertebrobasilar Occlusion
Symptoms of Vertebrobasilar Occlusion
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Vertebrobasilar Insufficiency
Vertebrobasilar Insufficiency
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Cerebral Veins
Cerebral Veins
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Superior Sagittal Sinus
Superior Sagittal Sinus
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Cranial Meninges
Cranial Meninges
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Subdural Hemorrhage (SDH)
Subdural Hemorrhage (SDH)
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Subarachnoid Hematoma (SAH)
Subarachnoid Hematoma (SAH)
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Lumbar Puncture (LP)
Lumbar Puncture (LP)
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Ischemic Stroke
Ischemic Stroke
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Hemorrhagic Stroke
Hemorrhagic Stroke
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Reperfusion
Reperfusion
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tPA/TNK
tPA/TNK
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Thrombectomy
Thrombectomy
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Anterior Cerebral Artery
Anterior Cerebral Artery
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Posterior Cerebral Artery
Posterior Cerebral Artery
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Hydrocephalus
Hydrocephalus
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Cerebral Aqueduct
Cerebral Aqueduct
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Lateral Ventricles
Lateral Ventricles
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Ventricular System
Ventricular System
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Dura Mater
Dura Mater
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Arachnoid Mater
Arachnoid Mater
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Pia Mater
Pia Mater
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Epidural Space
Epidural Space
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Subdural Space
Subdural Space
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Falx Cerebri
Falx Cerebri
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Tentorium Cerebelli
Tentorium Cerebelli
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Falx Cerebelli
Falx Cerebelli
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Dural Reflections
Dural Reflections
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Cerebrospinal Fluid
Cerebrospinal Fluid
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Meningitis
Meningitis
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Meningiomas
Meningiomas
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Epidural Hematoma
Epidural Hematoma
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Hyperacute Stage Symptoms
Hyperacute Stage Symptoms
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NIH Stroke Scale
NIH Stroke Scale
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NIH Stroke Scale Levels
NIH Stroke Scale Levels
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Imaging Tests Post-Stroke
Imaging Tests Post-Stroke
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Head CT Purpose
Head CT Purpose
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tPA Administration
tPA Administration
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Penumbra in Stroke
Penumbra in Stroke
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Hemorrhagic Conversion
Hemorrhagic Conversion
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Criteria for tPA
Criteria for tPA
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Limitations of MRIs
Limitations of MRIs
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CT vs. MRI in Stroke
CT vs. MRI in Stroke
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Acute Stroke Signs
Acute Stroke Signs
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Thrombectomy Purpose
Thrombectomy Purpose
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tPA Contraindications
tPA Contraindications
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Stroke Imaging Guidelines
Stroke Imaging Guidelines
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Study Notes
Cerebrum and Cerebral Cortex
- The cerebrum is responsible for higher-level functions like interpretation of senses, speech, reasoning, emotions, learning, and movement.
- It consists of two cerebral hemispheres and subcortical structures.
- The left hemisphere is typically dominant, controlling the right side of the body and associated with logic and analytical reasoning, and houses language centers. Broca's area is for verbal expression and speech production. Wernicke's area deals with verbal comprehension.
- The right hemisphere is non-dominant, controlling the left side of the body and associated with creativity, visual spatial processing, and facial recognition.
- The cerebral cortex is the outermost gray matter layer, heavily folded into gyri and sulci. It's divided into motor, sensory, and association areas.
- Motor areas include the primary motor cortex, premotor cortex, and supplementary motor cortex.
- Sensory areas include the primary somatosensory, primary visual, and auditory cortexes. Other areas are dedicated to smell, taste, and vestibular senses.
- Association areas integrate information from multiple brain regions for complex sensory perceptions, cognitive functions, and motor processes.
Cerebellum and Brainstem
- The cerebellum, located under the cerebrum, coordinates muscle movements and maintains posture and balance.
- The brainstem acts as a relay center connecting the cerebrum and cerebellum to the spinal cord.
Surface Features - Lobes and Landmarks
- Sulci (grooves) and gyri (ridges) divide the cerebral hemispheres into four lobes: frontal, parietal, temporal, and occipital.
- Lateral sulcus and central sulcus are major sulci.
- The central sulcus separates the frontal lobe from the parietal lobe.
- The parietal-occipital sulcus separates the parietal lobe from the occipital lobe.
- The cingulate sulcus and calcarine sulcus are other important sulci.
- Frontal lobe: responsible for cognitive and motor functions, including voluntary movement, executive functions (problem-solving, reasoning, planning, attention, and working memory), and expressive language (Broca's area).
- Parietal lobe: responsible for sensory perception and spatial awareness, including proprioception.
- Occipital lobe: processes visual information and contains the primary visual cortex.
- Temporal lobe: processes auditory information and is important for language comprehension (Wernicke's area), memory formation, and emotion regulation.
- Insular cortex: located deep within the lateral sulcus, integrating visceral, pain, and temperature sensations, involved in interoception, emotional processing, and other functions.
Corpus Callosum and Other Substructures
- The corpus callosum is a massive band of white matter connecting the cerebral hemispheres. Its components (from anterior to posterior) are the rostrum, genu, body, and splenium.
- The anterior commissure lies beneath the corpus callosum.
- Precentral gyri are entirely motor, while postcentral gyri are entirely sensory.
- The cingulate gyri is part of the limbic system and involved in behavior, pain, memory, attention, and autonomic motor function.
- Cuneus (wedge-shaped) plays a role in visual processing.
- The uncus is a hook-shaped structure in the temporal lobe, involved in memory, emotions, and smell.
- The thalamus is an egg-shaped structure that acts as a relay station for sensory and motor information from the body.
Surface Features - Inferior Aspect
- The longitudinal fissure separates the two cerebral hemispheres.
- The olfactory bulb processes smell information.
- The optic chiasm is where optic nerve fibers cross to allow both eyes' visual information to be processed by the occipital cortex.
- The midbrain is the topmost part of the brain stem and a connector between the brain and spinal cord.
- Temporal pole, frontal pole, occipital pole, and uncus are identifiable landmarks on the inferior aspect.
Functional Areas of the Cerebral Cortex
- Primary cortexes: receive information from various lobes to carry out body movements. Association with premotor regions plans and executes these movements.
- Premotor cortex: plans more complex movements by processing sensory information.
- Somatosensory cortex: receives touch and pressure information from the body via the thalamus and processes sensory information, spatial awareness.
- Occipital lobe: contains the primary visual area and language processing and reading areas (Wernicke's).
- Auditory cortex: in the temporal lobe, processes auditory information and is responsible for hearing.
- Broca's area: critical for speech production.
- Olfactory bulbs: process smell information.
Cortical Homunculi
- The cortical homunculus illustrates the distorted representation of body parts in the primary motor and somatosensory cortices to reflect the degree of precision/complexity of sensation or movement.
- Contralateral representations: One hemisphere of the brain controls and receives information from the opposite body side.
Brain Blood Supply
- The Circle of Willis is a ring-shaped network at the base of the brain, ensuring blood supply to all parts of the brain via alternative pathways in case of blockages.
- Major components: Anterior/posterior cerebral arteries, anterior communicating artery, internal carotid arteries, posterior cerebral arteries, posterior communicating arteries, basilar artery, and vertebral arteries.
- Arising from the internal carotid arteries are three main branches: Anterior Cerebral Artery (ACA), Middle Cerebral Artery (MCA), and Posterior Cerebral Artery(PCA).
- Anterior circulation (internal carotid arteries) supplies the majority of the cerebrum, with the largest artery being the MCA.
- Posterior circulation (vertebral and basilar arteries) supplies the brainstem and cerebellum.
- Cerebellar and brainstem vasculature includes the superior cerebellar artery, anterior inferior cerebellar artery (AICA), and posterior inferior cerebellar artery (PICA).
- These arteries have specific functions and areas supplied, with injuries yielding particular sets of neurological impairments.
Venous System of the Brain
- Cerebral veins drain blood from the brain to the dural sinuses.
- Dural sinuses are venous channels in the dura mater (eg. Superior sagittal sinus, transverse sinus, and sigmoid sinus).
- Drainage pathway: Superior sagittal sinus to transverse sinus to sigmoid sinus to internal jugular veins.
Cranial Meninges
- The meninges (dura mater, arachnoid mater, pia mater) surround and protect the CNS.
- Dura mater: thick, outermost layer, with two layers (meningeal and periosteal), houses dural sinuses and reflections.
- Arachnoid mater: thin, middle layer with trabeculae connecting to the pia mater and containing cerebrospinal fluid, providing a cushioning effect.
- Pia mater: innermost layer, tightly adhering to the brain's surface, highly vascularized, aiding in the blood-brain barrier and containing CSF.
- Cranial spaces include epidural, subdural, and subarachnoid.
- Meningitis, meningiomas, hematomas/hemorrhages (epidural, subdural, subarachnoid) are clinically relevant conditions.
Clinical Relevance of Stroke
- Stroke: is a leading cause of disability. Ischemic stroke occurs when a vessel is blocked; hemorrhagic stroke involves a blood vessel bursting.
- Common signs and symptoms: Sudden weakness/numbness, vision loss, speech difficulty, severe headache, dizziness/falls.
- NIH Stroke Scale: measures stroke severity via a neurological examination to predict outcomes.
- Acute stroke management: Imaging (CT, MRI, angiographies), clot-busting medications (tPA, TNK), thrombectomy for reperfusion.
- Stroke-Related Terminology: Penumbra (reversible tissue injury); hemorrhagic conversion (complication from tPA, reperfusion).
- Types of strokes with focus on blood vessels affected and associated symptoms.
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