Brachial Plexus Anatomy and Clinical Significance

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Questions and Answers

Explain how the anatomical positioning of the brachial plexus between the anterior and middle scalene muscles can make it vulnerable to compression injuries.

The brachial plexus passes through the narrow space between the anterior and middle scalene muscles, making it susceptible to compression if these muscles are tight or if there is an abnormal structure in this area.

Describe the functional consequence if the anterior division of the inferior trunk of the brachial plexus is damaged.

Damage to the anterior division of the inferior trunk primarily affects the nerves supplying the anterior compartment of the forearm and hand, leading to weakness in wrist and finger flexion, as well as sensory deficits in the medial aspect of the hand.

How would a lesion affecting the roots of C5 and C6 prior to their union impact both motor and sensory functions in the upper limb?

A lesion at this level causes weakness in the shoulder and upper arm muscles (deltoid, biceps), along with sensory loss along the lateral aspect of the arm. This is because C5 and C6 roots contribute to nerves innervating these areas.

Explain the clinical significance of the intercostobrachial nerve in the context of axillary lymph node dissection.

<p>The intercostobrachial nerve provides cutaneous innervation to the axilla and medial upper arm. During axillary lymph node dissection, this nerve is at risk of injury, potentially resulting in numbness, pain, or altered sensation in the affected area.</p> Signup and view all the answers

Describe a scenario where the anatomical relationship between the brachial plexus and the subclavian artery becomes clinically relevant.

<p>In cases of subclavian artery aneurysm or compression, the adjacent brachial plexus can be affected, leading to neurological symptoms in the upper limb due to pressure on the nerves. Similarly, during surgical procedures involving the subclavian artery, care must be taken to avoid injury to the surrounding plexus.</p> Signup and view all the answers

A patient presents with weakness in shoulder abduction and external rotation. Based on your knowledge of the brachial plexus, which specific nerve(s) and root(s) are most likely involved?

<p>The axillary nerve (C5, C6) is most likely involved, as it innervates the deltoid (abduction) and teres minor (external rotation) muscles. Damage to the suprascapular nerve (also C5, C6), which innervates the supraspinatus and infraspinatus muscles, could also contribute to weakness in abduction and external rotation.</p> Signup and view all the answers

Explain how a 'prefixed' brachial plexus differs from a 'postfixed' brachial plexus in terms of root contribution.

<p>A prefixed brachial plexus receives a greater contribution from C4 than T1, shifting the plexus origin superiorly (C4-C8), whereas a postfixed brachial plexus receives a greater contribution from T2, shifting the plexus origin inferiorly, with the superior root being C6.</p> Signup and view all the answers

A patient presents with weakness in abduction and external rotation of the arm. Which nerve is most likely affected, and how is this nerve related to the posterior cord of the brachial plexus?

<p>The axillary nerve is most likely affected. It is a terminal branch of the posterior cord of the brachial plexus and innervates the deltoid and teres minor muscles, responsible for abduction and external rotation respectively.</p> Signup and view all the answers

If the thoracodorsal nerve is damaged, which specific movement would be most noticeably impaired, and which muscle is primarily affected?

<p>Adduction, extension, and internal rotation of the arm would be most noticeably impaired. The latissimus dorsi muscle is primarily affected, as it is innervated by the thoracodorsal nerve.</p> Signup and view all the answers

Describe the path of the radial nerve after it branches from the posterior cord, and outline the general functional consequence of its damage.

<p>After branching from the posterior cord, the radial nerve passes out of the axilla and into the posterior compartment of the arm. Damage to the radial nerve typically results in impaired extension of the elbow, wrist, and fingers, as well as sensory loss on the posterior arm and forearm.</p> Signup and view all the answers

A patient has lost sensation on the palmar surface of their little finger and medial half of their ring finger, along with associated motor deficits in most intrinsic hand muscles. Which nerve is likely damaged?

<p>The ulnar nerve is likely damaged. It innervates the skin over these areas and most intrinsic hand muscles (excluding thenar muscles and two lumbricals).</p> Signup and view all the answers

Outline the course of the axillary nerve, including the anatomical space it traverses and the muscles it innervates.

<p>The axillary nerve, a terminal branch of the posterior cord, exits the axilla through the quadrangular space and passes posteriorly around the surgical neck of the humerus, innervating the teres minor and deltoid muscles.</p> Signup and view all the answers

Explain how the structure of the brachial plexus, specifically the arrangement of cords around the axillary artery, aids in accurately locating nerve damage during surgical procedures.

<p>The spatial relationship of the cords (lateral, medial, and posterior) relative to the axillary artery serves as a consistent anatomical reference. Surgeons can use this to identify and trace the cords, and their branches, to pinpoint the site and extent of nerve damage.</p> Signup and view all the answers

A patient presents with an inability to abduct their arm beyond 90 degrees and weakness in external rotation. Which specific nerve(s) originating from the supraclavicular branches of the brachial plexus are MOST likely affected?

<p>The suprascapular nerve (C5-6) is most likely affected. This nerve supplies the supraspinatus (responsible for initiating abduction) and infraspinatus (responsible for external rotation) muscles.</p> Signup and view all the answers

Describe the potential consequences of damage to the long thoracic nerve (C5-C7) and explain the resulting clinical presentation, including the specific anatomical reason for this presentation.

<p>Damage to the long thoracic nerve results in paralysis of the serratus anterior muscle. This causes 'winging' of the scapula, where the medial border of the scapula protrudes from the back because the serratus anterior can no longer hold it against the ribcage.</p> Signup and view all the answers

How does the anatomical course of the musculocutaneous nerve (C5-7) through the coracobrachialis muscle increase its vulnerability to injury, and what specific functional deficits would result from such an injury?

<p>The musculocutaneous nerve's passage through the coracobrachialis muscle makes it susceptible to compression or injury during trauma or surgery involving the shoulder. Damage results in weakened elbow flexion (biceps brachii and brachialis paralysis) and loss of cutaneous sensation along the lateral forearm.</p> Signup and view all the answers

A patient is diagnosed with a lesion affecting the anterior division of the inferior trunk of the brachial plexus. Which major nerve is MOST likely compromised and what specific motor function would be impaired as a result?

<p>The medial cord, which is a continuation of the anterior division of the inferior trunk, would be compromised. Given that the ulnar nerve is a terminal branch of the medial cord, fine motor control of the hand would be impaired due to deficits in the intrinsic hand muscles.</p> Signup and view all the answers

Explain why damage to the dorsal scapular nerve (C5) might be difficult to detect initially and how would you differentiate it from trapezius muscle impairment?

<p>Damage to the dorsal scapular nerve, innervating the rhomboids and levator scapulae, may initially be subtle as other muscles can compensate for scapular retraction. It can be differentiated from trapezius impairment (Spinal Accessory Nerve) because the trapezius is responsible for shoulder shrugging. Therefore, difficulty shrugging would not be present in dorsal scapular nerve injury.</p> Signup and view all the answers

A surgeon isolates the lateral cord during a procedure. What specific nerves can the surgeon expect to identify arising directly from this cord, and what muscles do these nerves innervate?

<p>The surgeon can expect to identify the lateral pectoral nerve and the musculocutaneous nerve arising from the lateral cord. The lateral pectoral nerve innervates the pectoralis major muscle, and the musculocutaneous nerve innervates the flexor muscles (biceps brachii, brachialis, coracobrachialis) in the anterior compartment of the arm.</p> Signup and view all the answers

Describe the anatomical path of the Suprascapular Nerve (C5-6) and explain how compression at the suprascapular notch can lead to isolated weakness in only external rotation of the shoulder.

<p>The suprascapular nerve passes through the suprascapular foramen (or notch). Compression at this notch can selectively affect the nerve's signal to the infraspinatus muscle <em>after</em> the nerve has already innervated the supraspinatus muscle. This results in isolated weakness in external rotation, while abduction strength (primarily supraspinatus) remains relatively intact.</p> Signup and view all the answers

Explain how the musculocutaneous nerve's path and innervation contribute to its susceptibility to injury, referencing specific muscles affected.

<p>The musculocutaneous nerve's path through the anterior compartment of the arm, innervating the biceps brachii, brachialis, and coracobrachialis, makes it vulnerable to injury. Trauma to the arm can directly impact these muscles, leading to impaired flexion and supination of the forearm.</p> Signup and view all the answers

Describe the clinical presentation one might expect from damage to the lateral root of the median nerve and explain why this presentation occurs.

<p>Damage to the lateral root of the median nerve may result in weakened wrist flexion, pronation, and thumb abduction and opposition, as it contributes to innervating muscles in the anterior forearm and thenar eminence. Numbness or paresthesia in the thumb, index, and middle fingers might also be present.</p> Signup and view all the answers

How would a lesion exclusively affecting the medial root of the median nerve differ in its presentation from a lesion affecting the median nerve distally at the wrist, such as in carpal tunnel syndrome?

<p>A lesion of the medial root would cause motor and sensory deficits in areas innervated by nerve branches originating from C8-T1. A lesion at the wrist would spare the forearm muscles but affect motor function and sensation in the hand.</p> Signup and view all the answers

Explain why damage to the median nerve in the forearm spares the flexor carpi ulnaris and the medial half of the flexor digitorum profundus, and which nerve innervates these muscles.

<p>The median nerve innervates most anterior forearm muscles except the flexor carpi ulnaris and medial half of the flexor digitorum profundus. These are innervated by the ulnar nerve, and therefore spared in damage to the median nerve.</p> Signup and view all the answers

Describe the specific sensory deficits a patient would experience with damage to the median nerve at the wrist, and explain why these deficits occur in the described distribution.

<p>Damage to the median nerve at the wrist would cause sensory loss over the palmar surface of the lateral three and one-half digits (thumb, index, middle, and radial half of the ring finger) and the lateral side of the palm. This distribution reflects the sensory innervation territory of the median nerve in the hand.</p> Signup and view all the answers

What functional impairments would result from damage to the thenar muscles due to median nerve injury, and how would these impairments affect hand function?

<p>Damage to the thenar muscles (abductor pollicis brevis, flexor pollicis brevis, opponens pollicis) due to median nerve injury would impair thumb abduction, flexion, and opposition. This significantly affects grip strength, precision pinch, and the ability to perform tasks requiring fine motor control.</p> Signup and view all the answers

Explain the functional significance of the lumbrical muscles innervated by the median nerve, and how their dysfunction manifests clinically.

<p>The two lateral lumbricals, innervated by the median nerve, flex the metacarpophalangeal joints and extend the interphalangeal joints of the index and middle fingers. Dysfunction leads to difficulty in performing fine motor tasks such as typing or playing musical instruments.</p> Signup and view all the answers

How does the anatomical relationship between the medial pectoral nerve, axillary artery, and axillary vein contribute to the potential for iatrogenic injury during surgical procedures in the axilla?

<p>The medial pectoral nerve passes anteriorly between the axillary artery and vein. During axillary surgeries, this close proximity increases the risk of nerve damage due to retraction, compression, or direct injury, potentially affecting the pectoralis minor and major muscles.</p> Signup and view all the answers

Explain the clinical relevance of the medial cutaneous nerve of the forearm being known as the 'fool's nerve'.

<p>The term 'fool's nerve' implies that patients may underestimate the impact of injury to the medial cutaneous nerve of the forearm. While purely sensory, damage can cause significant discomfort and altered sensation on the medial forearm, impacting daily activities despite not causing motor weakness.</p> Signup and view all the answers

Describe the path of the ulnar nerve as it traverses the arm and forearm, and how this path contributes to its vulnerability to injury at specific anatomical locations.

<p>The ulnar nerve travels through the arm and into the forearm without branching, making it vulnerable to injury at the elbow (cubital tunnel) and wrist (Guyon's canal). Compression or trauma at these points can affect its function, leading to motor and sensory deficits in the hand.</p> Signup and view all the answers

Flashcards

Brachial Plexus

Network of nerves for cutaneous and muscular innervation of the upper limb (except trapezius and axilla area).

Roots of Brachial Plexus

Lower four cervical nerves (C5-C8) and the greater part of the first thoracic nerve (T1).

Root Passage

Pass through the gap between the anterior and middle scalene muscles with the subclavian artery.

Brachial Plexus Trunks

Superior, middle and inferior; formed by the union of roots at the inferior border of the neck.

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Superior Trunk Formation

Formed by C5 & C6.

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Divisions of Trunks

Anterior divisions supply anterior compartments; posterior divisions supply posterior compartments.

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Lateral Cord

Formed by the union of anterior divisions of the superior and middle trunks.

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Medial Cord

Formed as a continuation of the anterior division of the inferior trunk.

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Posterior Cord

Formed by the union of the posterior divisions of the three trunks.

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Dorsal Scapular Nerve (C5)

Passes deep to supply the levator scapulae and rhomboids muscles.

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Suprascapular Nerve (C5-6)

Passes through suprascapular foramen; supplies supraspinatus, infraspinatus and glenohumeral joint.

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Nerve to Subclavius (C5-6)

Originates from the superior trunk; innervates the subclavius muscle.

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Long Thoracic Nerve (C5-C7)

Supplies the serratus anterior muscle.

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Lateral Pectoral Nerve (C5-7)

Innervates the pectoralis major muscle.

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Ulnar Nerve Function

Innervates all intrinsic hand muscles, except the thenar muscles and two lumbricals. Also supplies skin on the palmar surface of the little finger and medial ring finger.

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Upper Subscapular Nerve

Innervates the subscapularis muscle.

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Thoracodorsal Nerve

Innervates the latissimus dorsi muscle.

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Lower Subscapular Nerve

Innervates the teres major and inferior subscapularis muscles.

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Axillary Nerve Function

Innervates the teres minor and deltoid muscles.

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Radial Nerve Function

Supplies all extensor muscles in the posterior upper limb and skin on the posterior arm and forearm.

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Musculocutaneous Nerve

Innervates the Biceps brachii, Brachialis, and Coracobrachialis muscles; becomes the lateral cutaneous nerve of the forearm.

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Lateral Root of Median Nerve

Largest terminal branch of the lateral cord; joins the medial root to form the median nerve.

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Medial Root of Median Nerve

Joins the lateral root from the lateral cord to form the median nerve (C5-T1).

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Median Nerve Formation

Formed by the union of lateral and medial roots anterior to the third part of the axillary artery.

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Median Nerve (Forearm)

Innervates most anterior forearm muscles (except flexor carpi ulnaris and medial half of flexor digitorum profundus).

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Median Nerve (Hand)

Innervates the three thenar muscles of the thumb and the two lateral lumbricals.

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Medial Pectoral Nerve

Receives a branch from the lateral pectoral nerve; innervates pectoralis minor and part of pectoralis major.

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Medial Cutaneous Nerve of Arm

Supplies the skin of the medial arm and superior forearm, plus the floor of the axilla.

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Medial Cutaneous Nerve of Forearm

Innervates the skin on the medial side of the forearm.

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Ulnar Nerve (Forearm)

Innervates the flexor carpi ulnaris and the medial half of the flexor digitorum profundus in the forearm.

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Study Notes

Brachial Plexus Introduction

  • The brachial plexus is a network of nerves responsible for cutaneous and muscular innervation of the upper limb, with two exceptions.
  • The trapezius muscle is innervated by the spinal accessory nerve.
  • The area which is close to the axilla is innervated by the intercostobrachialis nerve.
  • The brachial plexus begins in the neck and extends through the axillary inlet into the axilla.
  • Most branches of the plexus arise after it has crossed the first rib.

Arrangement/Formation of the Plexus

  • The brachial plexus is formed by the union of the ventral rami of the lower four cervical nerves (C5-C8) and the first thoracic nerve (T1).
  • These roots pass through the gap between the anterior and middle scalene muscles with the subclavian artery.
  • The roots unite to form three trunks at the inferior border of the neck.
  • The superior trunk is formed by the union of C5 and C6 at the lateral border of the scalenus medius muscle.
  • The middle trunk is formed as a continuation of C7.
  • The inferior trunk is formed from the union of C8 & T1 posterior to the scalenius anterior muscle.
  • The three trunks incline laterally and divide into an anterior and a posterior division either just behind or above the clavicle.
  • The anterior division supplies the anterior compartments of the upper limb.
  • The posterior division supplies the extensor (posterior) compartment of the upper limb.
  • Six divisions unite to form three cords: lateral, medial and posterior.
  • The lateral cord is formed by the union of the anterior divisions of the superior and middle trunks.
  • The medial cord is formed as a continuation of the anterior division of the inferior trunk.
  • The posterior cord is formed by the union of the posterior divisions of the three trunks.
  • The cords' relationship to the second part of the axillary artery is indicated by their names.
  • The lateral cord is lateral to the axillary artery, the medial cord is medial to it, and the posterior cord is posterior to it.

Branches of the Plexus

  • Branches are described as supraclavicular and infraclavicular.
  • The supraclavicular branches arise from the roots and trunks and are approachable through the neck.

Supraclavicular Branches:

  • Dorsal Scapular Nerve (C5) pierces the middle scalene muscle and runs deep to supply the levator scapulae and rhomboids.
  • Suprascapular Nerve (C5-6) passes laterally through the posterior triangle of the neck and through the suprascapular foramen to enter the posterior scapular region.
  • It supplies the supraspinatus, infraspinatus muscles, and the glenohumeral joint.
  • Nerve to Subclavius (C5-6) originates from the superior trunk of the brachial plexus and innervates the subclavius muscle.
  • Long Thoracic Nerve (C5-C7) passes through the cervicoaxillary canal and posterior to other brachial plexus components to supply the serratus anterior muscle.

Infraclavicular Branches of the Plexus:

  • Lateral Cord: The lateral pectoral nerve (C5-C7) is the most proximal of its branches and innervates the pectoralis major muscle.
  • Musculocutaneous Nerve (C5-7) is a large terminal branch of the lateral cord.
  • It penetrates the coracobrachialis muscle and passes between the biceps brachii and brachialis muscles in the arm.
  • It innervates three flexor muscles in the anterior compartment of the arm (Biceps brachii, Brachialis and Coracobrachialis muscles), and continues as the lateral cutaneous nerve of the forearm.
  • Lateral Root of Median Nerve (C5-7): this is the largest terminal branch of the lateral cord, and passes medially to join a similar branch from the medial cord to form the median nerve.
  • Medial Cord: The medial root of the median nerve (C8-T1) joins the lateral roots from the lateral cord to form the median nerve (C5-T1).
  • The median nerve is formed anterior to the third part of the axillary artery by the union of lateral and medial roots originating from the lateral and medial cords of the brachial plexus.
  • It passes into the arm anterior to the brachial artery, through the arm into the forearm.
  • Branches innervate most of the muscles in the anterior compartment of the forearm, but the flexor carpi ulnaris muscle and the medial half of the flexor digitorum profundus muscle are innervated by the ulnar nerve.
  • The median nerve continues into the hand to innervate the three thenar muscles associated with the thumb, and the two lateral lumbrical muscles associated with movement of the index and middle fingers.
  • The median nerve also innervates the skin over the palmar surface of the lateral three and one-half digits as well as the lateral side of the palm and middle of the wrist.
  • Medial Pectoral Nerve (C8-T1) receives a communicating branch from the lateral pectoral nerve and then passes anteriorly between the axillary artery and axillary vein.
  • It innervates the pectoralis minor muscle and part of the pectoralis major muscle.
  • Medial Cutaneous Nerve of the arm (C8-T1) , supplies the skin of the medial side of the arm and superior part of the forearm and also the floor of the axilla.
  • Medial Cutaneous Nerve of the Forearm (C8-T1), innervates the skin on the medial side of the forearm, which is also known as the "fools nerve".
  • Ulnar Nerve (C8-T1) , a large terminal branch of the medial cord transverse the arm into the forearm without branching.
  • It innervates one and a half muscles in the anterior compartment of the forearm (flexor carpi ulnaris, flexor digitorum profundus).
  • It also innervates all the intrinsic muscles of the hand except the three thenar muscles and two lumbricals.
  • It innervates the skin over the palmar surface of the little finger and medial half of the ring finger, associated palm and wrist, and the skin over the dorsal surface of the medial part of the hand.
  • Posterior Cord: The upper subscapular nerve (C5-6) is short passing into the subscapularis muscle, innervating it.
  • The thoracodorsal nerve (C6-8) is the longest of the three side branches of the posterior cord.
  • It passes vertically along the posterior axillary wall, and innervates latissimus dorsi.
  • The lower subscapular nerve (C5-6) innervates the teres major muscle as well as the inferior part of the subscapularis muscle.
  • Axillary Nerve (C5-6) is a terminal branch of the posterior cord, it exits the axilla through the quadrangular space, and it passes posteriorly around the surgical neck of the humerus.
  • It innervates the teres minor muscle and the deltoid muscle.
  • Radial Nerve (C5-8, T1) is the largest terminal branch of the posterior cord.
  • This is the largest branch of the brachial plexus.
  • It passes out of the axilla and into the posterior compartment of the arm, it supplies all the extensor muscles of the posterior compartment of the upper limb, as well as the skin on the posterior aspect of the arm and forearm.

Variations in the Formation of the Brachial Plexus

  • Variations in the formations of the brachial plexus are common.
  • In addition to the five (5) ventral rami (C5-8) and T1 that form the roots of the brachial plexus, small contributions may be made by the ventral ramus of C4 or T2.
  • In cases where the contribution from C4 is more than T1, the root of the plexus starts from C4 and ends at C8 and this type of brachial plexus is termed prefixed.
  • In cases where the contribution from T2 is more than C4 and the superior root is C6, it is termed postfixed.
  • Variation also occurs in the formation of trunks, divisions and cords, the origin and contribution of branches, the relation to the axillary artery and scalene muscle, and in other ways.
  • In some individuals, divisions, trunk or cord formations may be absent in one or other parts of the plexus; however the make up of the terminal branches remain unchanged.

Relationships of Some Brachial Nerves to Bones

  • Surgical neck of the humerus: the Axillary nerve which supplies the deltoid and teres minor muscles is a major abductor of the humerus at the shoulder joint.
  • Radial groove contains the radial nerve which supplies all the extensor muscles of the upper limb.
  • Medial epicondyle has the ulnar nerve that supplies the medial one and a half part of the hand and the anterior compartment of the forearm.

Clinical and Applied Anatomy of the Brachial Plexus

  • The brachial plexus is an extremely complex structure, and when damaged it requires meticulous taking of clinical history and examination.
  • Brachial plexus injuries are important, as they can affect movements and cutaneous sensations in the upper limb.
  • Diseases, stretching, and wounds in the posterior triangle of the neck or in the axilla may produce brachial plexus injury.
  • Signs and symptoms of injuries depends on the side of the plexus that is involved.
  • Injuries to superior parts of the brachial plexus (C5 and C6) usually result from an excessive increase in the angle between the neck and the shoulder.
  • This can occur when a person is thrown from a motorcycle or horse and lands on the shoulder in a way that widely separates the neck and shoulder.
  • Injury to the superior trunk of the plexus is apparent by the characteristic position of the limb (“waiter’s tip position”), in which the limb hangs by the side in medial rotation.
  • Upper brachial plexus injuries may occur in newborns because of excessive stretching of the neck during delivery.
  • Terms for superior brachial plexus injuries include Erb palsy or paralysis, Erb-Duchenne palsy or paralysis, Duchenne-Erb palsy or paralysis, and upper radicular syndrome.
  • The inferior parts of the brachial plexus may also be injured during a breech birth when the limb is pulled over the head.
  • This injures the inferior trunk of the brachial plexus (C8-T1), potentially pulling the spinal nerves’ dorsal and ventral roots from the spinal cord.
  • As a result The short muscles of the hand are affected, and a "claw hand" can result from the trauma.

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