BPH Quiz

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Questions and Answers

Which of the following is a common symptom of benign prostatic hyperplasia (BPH)?

  • Difficulty in breathing
  • Increased appetite
  • Chest pain
  • Difficulty in urination (correct)

Which grade of benign prostatic hyperplasia (BPH) is characterized by permanent micturition disturbance and a maximal urinary flow of less than 10ml/sec?

  • Grade 1
  • Grade 4 (correct)
  • Grade 3
  • Grade 2

What is the recommended therapy for Grade II phase of benign prostatic hyperplasia (BPH)?

  • Alcohol abstinence and avoiding low temperature
  • Pharmacotherapy or phytotherapy
  • Spasmolytics and bowel regulation (correct)
  • Surgery: TURP or prostatectomy

Which plants are used for treatment in therapy?

<p>Both Serenoa Repens and Prunus Africana (C)</p> Signup and view all the answers

What are the important constituents of Serenoa Repens (Saw Palmetto)?

<p>Fatty acid and Phytosterols (β-sitosterol) (A)</p> Signup and view all the answers

What undesirable effect may occur when using Serenoa Repens (Saw Palmetto)?

<p>All of the above (D)</p> Signup and view all the answers

Which one of the following is a common symptom of benign prostatic hyperplasia (BPH)?

<p>Increased frequency of urination (A)</p> Signup and view all the answers

Which grade of benign prostatic hyperplasia (BPH) is characterized by intermittent micturition disturbance and a maximal urinary flow of 10-15ml/sec?

<p>Grade II, phase of growth (B)</p> Signup and view all the answers

What is the recommended therapy for Grade III residual volume phase of benign prostatic hyperplasia (BPH)?

<p>Pharmacotherapy or phytotherapy (D)</p> Signup and view all the answers

Which enzyme does Serenoa Repens (Saw Palmetto) inhibit in the prostate?

<p>5α-reductase (A)</p> Signup and view all the answers

What is the pharmacotherapeutic group of Serenoa Repens (Saw Palmetto)?

<p>Benign prostatic hyperplasia (C)</p> Signup and view all the answers

Which medicinal product has been reported to have potential interactions with Serenoa Repens (Saw Palmetto)?

<p>Warfarin (C)</p> Signup and view all the answers

Which of the following is a common symptom of benign prostatic hyperplasia (BPH)?

<p>Frequent urination (C)</p> Signup and view all the answers

What is the recommended therapy for Grade I phase of benign prostatic hyperplasia (BPH)?

<p>Bowel regulation and abstinence of alcohol (A)</p> Signup and view all the answers

Which enzyme does Serenoa Repens (Saw Palmetto) inhibit in the prostate?

<p>5-alpha-reductase (A)</p> Signup and view all the answers

Which plant is used for treatment of benign prostatic hyperplasia (BPH) and inhibits the enzyme responsible for converting testosterone to dihydrotestosterone in the prostate?

<p>Serenoa Repens (Saw Palmetto) (D)</p> Signup and view all the answers

Which plant contains a specific androgen receptor antagonist and esters of ferulic acid with anti-inflammatory effects?

<p>Prunus Africana (Pruni Africani Cortex) (C)</p> Signup and view all the answers

Which plant has the potential to interact with warfarin and may increase INR values?

<p>Serenoa Repens (Saw Palmetto) (D)</p> Signup and view all the answers

What is the main activity of Serenoa Repens (Saw Palmetto) in the prostate?

<p>Inhibition of 5α-reductase (D)</p> Signup and view all the answers

Which undesirable effect may occur when using Serenoa Repens (Saw Palmetto)?

<p>GI disorders (nausea, abdominal pain) (C)</p> Signup and view all the answers

Which grade of benign prostatic hyperplasia (BPH) is characterized by a bladder wall that starts to be thickened?

<p>Grade II, phase of growth (B)</p> Signup and view all the answers

What is the recommended therapy for Grade III residual volume phase of benign prostatic hyperplasia (BPH)?

<p>Pharmacotherapy or phytotherapy (B)</p> Signup and view all the answers

Which symptom is associated with Grade IV phase of benign prostatic hyperplasia (BPH)?

<p>Permanent micturition disturbance, maximal urinary flow &lt;10ml/sec, residual urinary volume &gt;100ml (A)</p> Signup and view all the answers

Which grade of benign prostatic hyperplasia (BPH) is characterized by a bladder wall that starts to be thickened?

<p>Grade II (C)</p> Signup and view all the answers

Which enzyme does Serenoa Repens (Saw Palmetto) inhibit in the prostate?

<p>5-alpha reductase (B)</p> Signup and view all the answers

Which plant is used for the treatment of benign prostatic hyperplasia (BPH)?

<p>Serenoa Repens (Saw Palmetto) (B)</p> Signup and view all the answers

What are the important constituents of Serenoa Repens (Saw Palmetto)?

<p>Fatty acid and Phytosterols (β-sitosterol) (D)</p> Signup and view all the answers

Which undesirable effect may occur when using Serenoa Repens (Saw Palmetto)?

<p>All of the above (D)</p> Signup and view all the answers

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Study Notes

Benign Prostatic Hyperplasia (BPH)

  • A common symptom of BPH is nocturia (frequent nighttime urination)

BPH Grades

  • Grade I: characterized by minimal symptoms
  • Grade II: characterized by intermittent micturition disturbance and a maximal urinary flow of 10-15ml/sec
  • Grade III: characterized by permanent micturition disturbance and a maximal urinary flow of less than 10ml/sec
  • Grade IV: characterized by a bladder wall that starts to be thickened, and symptoms such as urinary retention and incontinence

Treatment of BPH

  • Recommended therapy for Grade I BPH: watchful waiting
  • Recommended therapy for Grade II BPH: medical therapy
  • Recommended therapy for Grade III residual volume BPH: surgery

Serenoa Repens (Saw Palmetto)

  • Used for treatment of BPH
  • Important constituents: phytosterols, fatty acids, and flavonoids
  • Inhibits the enzyme 5-alpha-reductase in the prostate, which converts testosterone to dihydrotestosterone
  • Pharmacotherapeutic group: plant-based medication
  • May interact with warfarin and increase INR values
  • Undesirable effect: gastrointestinal disturbances

Other Plants Used for BPH Treatment

  • Some plants used for BPH treatment inhibit the enzyme responsible for converting testosterone to dihydrotestosterone in the prostate
  • Some plants contain specific androgen receptor antagonists and esters of ferulic acid with anti-inflammatory effects

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