Podcast
Questions and Answers
What passes through the fenestrations into Bowman's space?
What passes through the fenestrations into Bowman's space?
What prevents giant proteins in red and white blood cells from leaking through?
What prevents giant proteins in red and white blood cells from leaking through?
What type of cells are the tubule cells that help line the nephron?
What type of cells are the tubule cells that help line the nephron?
What happens to the rate of filtration if the diameter of the afferent arteriole is increased?
What happens to the rate of filtration if the diameter of the afferent arteriole is increased?
Signup and view all the answers
What happens to the filtration rate if the diameter of the efferent arteriole is increased?
What happens to the filtration rate if the diameter of the efferent arteriole is increased?
Signup and view all the answers
What can be compared to a marathon in terms of blood flow in the glomerulus?
What can be compared to a marathon in terms of blood flow in the glomerulus?
Signup and view all the answers
What is the effect of decreasing the diameter of the afferent arteriole on the filtration rate?
What is the effect of decreasing the diameter of the afferent arteriole on the filtration rate?
Signup and view all the answers
What is the function of podocytes in the nephron?
What is the function of podocytes in the nephron?
Signup and view all the answers
What happens to the filtration rate if the diameter of the efferent arteriole is decreased?
What happens to the filtration rate if the diameter of the efferent arteriole is decreased?
Signup and view all the answers
What is Bowman's space?
What is Bowman's space?
Signup and view all the answers
Why is it unusual to have an arteriole giving off another arteriole?
Why is it unusual to have an arteriole giving off another arteriole?
Signup and view all the answers
What is the term for a very narrow or stenosed vessel?
What is the term for a very narrow or stenosed vessel?
Signup and view all the answers
What is the result of renal artery stenosis on the filtration rate?
What is the result of renal artery stenosis on the filtration rate?
Signup and view all the answers
What happens to the ions, amino acids, and glucose in the blood if the diameter of the efferent arteriole is decreased?
What happens to the ions, amino acids, and glucose in the blood if the diameter of the efferent arteriole is decreased?
Signup and view all the answers
What is the purpose of learning about what can go wrong with the filtration process?
What is the purpose of learning about what can go wrong with the filtration process?
Signup and view all the answers
What is the term for the space where filtered substances are collected?
What is the term for the space where filtered substances are collected?
Signup and view all the answers
Study Notes
Bowman's Space and Filtration
- Smaller ions, amino acids, glucose, and water can leak through fenestrations into Bowman's space.
- Podocytes hug the arterioles by holding onto endothelial cells.
- The basement membrane prevents giant proteins in red and white blood cells from leaking through.
- Tubule cells, which are epithelial cells, line the other side of Bowman's space.
Afferent and Efferent Arterioles
- An increase in the diameter of the afferent arteriole increases the rate of filtration, as more blood flows into the glomerulus.
- A decrease in the diameter of the afferent arteriole decreases the rate of filtration, as less blood flows into the glomerulus.
- An increase in the diameter of the efferent arteriole decreases the rate of filtration, as blood flows away from the glomerulus more quickly.
- A decrease in the diameter of the efferent arteriole increases the rate of filtration, as blood backs up and spends more time near the fenestrations.
Effects on Filtration Rate
- Renal artery stenosis (narrowing of the renal artery) decreases the filtration rate, as less blood flows into the afferent arteriole.
- Decreasing the diameter of the efferent arteriole can increase the filtration rate, as blood backs up and spends more time near the fenestrations.
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
Description
Understand the structure and function of Bowman's space in the nephron, including the role of podocytes and endothelial cells in filtering ions and glucose.
