Bowel Neoplasms

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72 Questions

Which type of tumour arises from smooth muscle in the gastrointestinal tract?

Leiomyoma

Which site in the bowel is more likely to have low-grade neuroendocrine tumours?

Appendix

Which type of tumour is the most important entity to discuss in the context of colorectal diseases?

Carcinoma

Which of the following is a descriptive term for a large bowel adenocarcinoma that means 'mushroom-like'?

Fungating

What is the most common type of cancer that occurs in the bowel?

Adenocarcinoma

What is the second most common cancer in men?

Bowel cancer

What is the lifetime risk of dying from bowel cancer?

1 in 46

Which of the following is NOT a type of epithelial polyp that may occur in the bowel?

Malignant polyps

Which of the following is NOT a contributing factor to the development of colorectal carcinoma?

Epigenetics

Which of the following is NOT a common non-epithelial neoplasm of the large bowel?

Adenocarcinoma

Which of the following is a key factor in the development of colorectal adenocarcinoma?

Familial cancer syndromes

Which pathway is involved in the development of colorectal adenocarcinoma?

APC, p53, KRAS pathway

What is the main purpose of the National Bowel Cancer Screening Program?

To identify patients with cancer or precursor lesions early

What is the precursor lesion in most colorectal carcinomas?

Adenomas

Which of the following is NOT a type of benign epithelial tumor or precursor included in the classification of bowel neoplasms?

Gastrointestinal stromal tumors

Which of the following is classified as a malignant epithelial tumor in the classification of bowel neoplasms?

Medullary adenocarcinoma

Which of the following is NOT a type of mesenchymal tumor included in the classification of bowel neoplasms?

Schwannoma

Which of the following is NOT a type of neuroendocrine tumor included in the classification of bowel neoplasms?

Mucosal melanoma

Which of the following is NOT a type of malignant epithelial tumor included in the classification of bowel neoplasms?

Adenoma

Which of the following locations in the bowel is more likely to have leiomyosarcoma?

Serosa

Which of the following sites in the bowel is more likely to have a higher risk of gastrointestinal stromal tumour?

Submucosa

Which of the following is a risk factor for bowel cancer?

Obesity

What is the most common type of cancer that occurs in the bowel?

Adenocarcinoma

What is the second most common cancer in women?

Bowel cancer

What is the lifetime risk of dying from bowel cancer?

1 in 46

Which of the following is NOT a common type of epithelial polyp that may occur in the bowel?

Malignant polyp

What is the main purpose of the National Bowel Cancer Screening Program?

To detect early signs of colorectal cancer

Which of the following is NOT a contributing factor to the development of colorectal carcinoma?

Epigenetics

Which of the following is NOT a precursor lesion of colon adenocarcinoma?

Lynch syndrome

What is the main pathway involved in the development of colorectal adenocarcinoma?

APC pathway

What is the main purpose of the National Bowel Cancer Screening Program?

To detect and diagnose colorectal adenocarcinoma

Which of the following is NOT a contributing factor to the development of colorectal carcinoma?

Epigenetics

Which of the following is NOT a type of benign epithelial tumor or precursor included in the classification of bowel neoplasms?

Inflammatory myofibroblastic tumor

What is the main purpose of the National Bowel Cancer Screening Program?

To detect and prevent bowel cancer

Which of the following is NOT a type of mesenchymal tumor included in the classification of bowel neoplasms?

Ganglioneuroma

What is the lifetime risk of dying from bowel cancer?

1 in 10

Which of the following is a potential site of origin for tumours in the bowel?

Muscularis

Which of the following is NOT a potential precursor lesion of colon adenocarcinoma?

Carcinoma

Which of the following is a key factor in the development of colorectal adenocarcinoma?

Mitotic activity

Which of the following is NOT a precursor lesion of colon adenocarcinoma?

Familial cancer syndromes

Which of the following is NOT a common risk factor for the development of colorectal carcinoma?

Epigenetics

Which of the following is NOT a common non-epithelial neoplasm of the large bowel?

Leiomyosarcoma

Which of the following is NOT a contributing factor to the development of colorectal carcinoma?

Familial cancer syndromes

Which type of tumour is the most important entity to discuss in the context of colorectal diseases?

Adenocarcinoma

Which of the following is NOT a type of benign epithelial tumor or precursor included in the classification of bowel neoplasms?

Neuroendocrine tumour

Which of the following is NOT a risk factor for developing bowel cancer?

Family history of bowel cancer

What is the most common type of cancer that occurs in the bowel?

Adenocarcinoma

What is the second most common cancer in men?

Colorectal cancer

Which of the following is NOT a type of benign epithelial tumor or precursor included in the classification of bowel neoplasms?

Inflammatory polyp

What is the lifetime risk of dying from bowel cancer?

1 in 46

Which of the following is NOT a type of malignant epithelial tumor included in the classification of bowel neoplasms?

Medullary adenocarcinoma

Which of the following is NOT a type of mesenchymal tumor included in the classification of bowel neoplasms?

Rhabdomyosarcoma

Which of the following is NOT a type of neuroendocrine tumor included in the classification of bowel neoplasms?

PP/PYY-producing tumor

Which of the following is NOT a type of benign epithelial tumor or precursor included in the classification of bowel neoplasms?

Gastrointestinal stromal tumors

Which of the following is a malignant epithelial tumor included in the classification of bowel neoplasms?

Carcinoma

Which of the following is a risk factor for developing bowel cancer?

Smoking

What is the most common type of cancer that occurs in the bowel?

Carcinoma

Which of the following is NOT a potential precursor lesion of colon adenocarcinoma?

Hyperplastic polyps

Which of the following is a descriptive term for a large bowel adenocarcinoma that means 'mushroom-like'?

Villous adenoma

Which site in the bowel is more likely to have low-grade neuroendocrine tumours?

Rectum

Which of the following is NOT a common risk factor for the development of bowel cancer?

Smoking

What is the second most common cancer in men?

Bowel cancer

What is the lifetime risk of dying from bowel cancer?

1 in 46

Which of the following is NOT a type of malignant epithelial tumor included in the classification of bowel neoplasms?

Lymphoma

Which of the following is NOT a contributing factor to the development of colorectal carcinoma?

Familial cancer syndromes

What is the main purpose of the National Bowel Cancer Screening Program?

To detect FOB in asymptomatic individuals

Which of the following is the most common type of epithelial polyp that may occur in the bowel?

Benign polyps

What is the second most common cancer in women?

Colorectal cancer

Which of the following is NOT a type of neuroendocrine tumor included in the classification of bowel neoplasms?

Somatostatin-producing tumor

Which of the following is NOT a type of malignant epithelial tumor included in the classification of bowel neoplasms?

Medullary adenocarcinoma

Which of the following is NOT a type of mesenchymal tumor included in the classification of bowel neoplasms?

Rhabdomyosarcoma

Which of the following is NOT a type of benign epithelial tumor or precursor included in the classification of bowel neoplasms?

Tubulovillous adenocarcinoma

Study Notes

Classification of Bowel Neoplasms (WHO 5th Edition, 2019)

  • The classification includes various types of benign and malignant tumors in the bowel.
  • Benign epithelial tumors and precursors include hyperplastic polyps, serrated dysplasia, adenomatous polyps, tubular adenomas, villous adenomas, and tubulovillous adenomas.
  • Gastrointestinal stromal tumors and adipose tissue and (myo)fibroblastic tumors are also classified.
  • Malignant epithelial tumors include adenocarcinoma, adenoma-like adenocarcinoma, micropapillary adenocarcinoma, mucinous adenocarcinoma, poorly cohesive carcinoma, signet ring cell carcinoma, medullary adenocarcinoma, adenosquamous carcinoma, carcinoma with sarcomatoid component, and undifferentiated carcinoma.
  • Mesenchymal tumors, such as inflammatory myofibroblastic tumor, desmoid fibromatosis, solitary fibrous tumor, lipoma, inflammatory fibroid polyp, plexiform fibromyxoma, leiomyoma, leiomyosarcoma, rhabdomyosarcoma, haemangioma, and glomus tumor, are also included.
  • Neural tumors like schwannoma, granular cell tumor, perineurioma, ganglioneuroma, and ganglioneuromatosis are part of the classification.
  • Site-specific hematolymphoid tumors, including MALT lymphoma, duodenal-type follicular lymphoma, enteropathy-associated T-cell lymphoma, and intestinal T-cell lymphoma, are categorized.
  • Haematolymphoid tumors occurring with some frequency in the digestive system, such as diffuse large B-cell lymphoma, follicular lymphoma, mantle cell lymphoma, Burkitt lymphoma, plasmablastic lymphoma, and posttransplant lymphoproliferative disorders, are included.
  • Neuroendocrine tumors are classified based on grade, including grade 1, grade 2, grade 3, L cell tumor, glucagon-like peptide-producing tumor, PP/PYY-producing tumor, and enterochromaffin cell carcinoid.
  • Tumors of uncertain differentiation, such as hematolymphoid tumors, PEComa, synovial sarcoma, and gastrointestinal clear cell sarcoma/malignant gastrointestinal neuroectodermal tumor, are also categorized.
  • Other tumors of the digestive system, including mucosal melanoma, serotonin-producing carcinoid, germ cell tumors, neuroendocrine carcinoma, and digestive system metastases, are included.
  • The simplified classification of bowel neoplasms includes categories for epithelial tumors (benign and malignant), neuroendocrine tumors, mesenchymal tumors, and others.

Classification of Bowel Neoplasms (WHO 5th Edition, 2019)

  • The classification includes various types of benign and malignant tumors in the bowel.
  • Benign epithelial tumors and precursors include hyperplastic polyps, serrated dysplasia, adenomatous polyps, tubular adenomas, villous adenomas, and tubulovillous adenomas.
  • Gastrointestinal stromal tumors and adipose tissue and (myo)fibroblastic tumors are also classified.
  • Malignant epithelial tumors include adenocarcinoma, adenoma-like adenocarcinoma, micropapillary adenocarcinoma, mucinous adenocarcinoma, poorly cohesive carcinoma, signet ring cell carcinoma, medullary adenocarcinoma, adenosquamous carcinoma, carcinoma with sarcomatoid component, and undifferentiated carcinoma.
  • Mesenchymal tumors, such as inflammatory myofibroblastic tumor, desmoid fibromatosis, solitary fibrous tumor, lipoma, inflammatory fibroid polyp, plexiform fibromyxoma, leiomyoma, leiomyosarcoma, rhabdomyosarcoma, haemangioma, and glomus tumor, are also included.
  • Neural tumors like schwannoma, granular cell tumor, perineurioma, ganglioneuroma, and ganglioneuromatosis are part of the classification.
  • Site-specific hematolymphoid tumors, including MALT lymphoma, duodenal-type follicular lymphoma, enteropathy-associated T-cell lymphoma, and intestinal T-cell lymphoma, are categorized.
  • Haematolymphoid tumors occurring with some frequency in the digestive system, such as diffuse large B-cell lymphoma, follicular lymphoma, mantle cell lymphoma, Burkitt lymphoma, plasmablastic lymphoma, and posttransplant lymphoproliferative disorders, are included.
  • Neuroendocrine tumors are classified based on grade, including grade 1, grade 2, grade 3, L cell tumor, glucagon-like peptide-producing tumor, PP/PYY-producing tumor, and enterochromaffin cell carcinoid.
  • Tumors of uncertain differentiation, such as hematolymphoid tumors, PEComa, synovial sarcoma, and gastrointestinal clear cell sarcoma/malignant gastrointestinal neuroectodermal tumor, are also categorized.
  • Other tumors of the digestive system, including mucosal melanoma, serotonin-producing carcinoid, germ cell tumors, neuroendocrine carcinoma, and digestive system metastases, are included.
  • The simplified classification of bowel neoplasms includes categories for epithelial tumors (benign and malignant), neuroendocrine tumors, mesenchymal tumors, and others.

Classification of Bowel Neoplasms (WHO 5th Edition, 2019)

  • The classification includes various types of benign and malignant tumors in the bowel.
  • Benign epithelial tumors and precursors include hyperplastic polyps, serrated dysplasia, adenomatous polyps, tubular adenomas, villous adenomas, and tubulovillous adenomas.
  • Gastrointestinal stromal tumors and adipose tissue and (myo)fibroblastic tumors are also classified.
  • Malignant epithelial tumors include adenocarcinoma, adenoma-like adenocarcinoma, micropapillary adenocarcinoma, mucinous adenocarcinoma, poorly cohesive carcinoma, signet ring cell carcinoma, medullary adenocarcinoma, adenosquamous carcinoma, carcinoma with sarcomatoid component, and undifferentiated carcinoma.
  • Mesenchymal tumors, such as inflammatory myofibroblastic tumor, desmoid fibromatosis, solitary fibrous tumor, lipoma, inflammatory fibroid polyp, plexiform fibromyxoma, leiomyoma, leiomyosarcoma, rhabdomyosarcoma, haemangioma, and glomus tumor, are also included.
  • Neural tumors like schwannoma, granular cell tumor, perineurioma, ganglioneuroma, and ganglioneuromatosis are part of the classification.
  • Site-specific hematolymphoid tumors, including MALT lymphoma, duodenal-type follicular lymphoma, enteropathy-associated T-cell lymphoma, and intestinal T-cell lymphoma, are categorized.
  • Haematolymphoid tumors occurring with some frequency in the digestive system, such as diffuse large B-cell lymphoma, follicular lymphoma, mantle cell lymphoma, Burkitt lymphoma, plasmablastic lymphoma, and posttransplant lymphoproliferative disorders, are included.
  • Neuroendocrine tumors are classified based on grade, including grade 1, grade 2, grade 3, L cell tumor, glucagon-like peptide-producing tumor, PP/PYY-producing tumor, and enterochromaffin cell carcinoid.
  • Tumors of uncertain differentiation, such as hematolymphoid tumors, PEComa, synovial sarcoma, and gastrointestinal clear cell sarcoma/malignant gastrointestinal neuroectodermal tumor, are also categorized.
  • Other tumors of the digestive system, including mucosal melanoma, serotonin-producing carcinoid, germ cell tumors, neuroendocrine carcinoma, and digestive system metastases, are included.
  • The simplified classification of bowel neoplasms includes categories for epithelial tumors (benign and malignant), neuroendocrine tumors, mesenchymal tumors, and others.

Classification of Bowel Neoplasms (WHO 5th Edition, 2019)

  • The classification includes various types of benign and malignant tumors in the bowel.
  • Benign epithelial tumors and precursors include hyperplastic polyps, serrated dysplasia, adenomatous polyps, tubular adenomas, villous adenomas, and tubulovillous adenomas.
  • Gastrointestinal stromal tumors and adipose tissue and (myo)fibroblastic tumors are also classified.
  • Malignant epithelial tumors include adenocarcinoma, adenoma-like adenocarcinoma, micropapillary adenocarcinoma, mucinous adenocarcinoma, poorly cohesive carcinoma, signet ring cell carcinoma, medullary adenocarcinoma, adenosquamous carcinoma, carcinoma with sarcomatoid component, and undifferentiated carcinoma.
  • Mesenchymal tumors, such as inflammatory myofibroblastic tumor, desmoid fibromatosis, solitary fibrous tumor, lipoma, inflammatory fibroid polyp, plexiform fibromyxoma, leiomyoma, leiomyosarcoma, rhabdomyosarcoma, haemangioma, and glomus tumor, are also included.
  • Neural tumors like schwannoma, granular cell tumor, perineurioma, ganglioneuroma, and ganglioneuromatosis are part of the classification.
  • Site-specific hematolymphoid tumors, including MALT lymphoma, duodenal-type follicular lymphoma, enteropathy-associated T-cell lymphoma, and intestinal T-cell lymphoma, are categorized.
  • Haematolymphoid tumors occurring with some frequency in the digestive system, such as diffuse large B-cell lymphoma, follicular lymphoma, mantle cell lymphoma, Burkitt lymphoma, plasmablastic lymphoma, and posttransplant lymphoproliferative disorders, are included.
  • Neuroendocrine tumors are classified based on grade, including grade 1, grade 2, grade 3, L cell tumor, glucagon-like peptide-producing tumor, PP/PYY-producing tumor, and enterochromaffin cell carcinoid.
  • Tumors of uncertain differentiation, such as hematolymphoid tumors, PEComa, synovial sarcoma, and gastrointestinal clear cell sarcoma/malignant gastrointestinal neuroectodermal tumor, are also categorized.
  • Other tumors of the digestive system, including mucosal melanoma, serotonin-producing carcinoid, germ cell tumors, neuroendocrine carcinoma, and digestive system metastases, are included.
  • The simplified classification of bowel neoplasms includes categories for epithelial tumors (benign and malignant), neuroendocrine tumors, mesenchymal tumors, and others.

Test your knowledge of the Classification of Bowel Neoplasms according to the WHO 5th Edition in this quiz. Explore various types of benign and malignant tumors in the bowel, including epithelial tumors, mesenchymal tumors, neural tumors, hematolymphoid tumors, and more. Expand your understanding of the classification of bowel neoplasms with this informative quiz.

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