72 Questions
Which type of tumour arises from smooth muscle in the gastrointestinal tract?
Leiomyoma
Which site in the bowel is more likely to have low-grade neuroendocrine tumours?
Appendix
Which type of tumour is the most important entity to discuss in the context of colorectal diseases?
Carcinoma
Which of the following is a descriptive term for a large bowel adenocarcinoma that means 'mushroom-like'?
Fungating
What is the most common type of cancer that occurs in the bowel?
Adenocarcinoma
What is the second most common cancer in men?
Bowel cancer
What is the lifetime risk of dying from bowel cancer?
1 in 46
Which of the following is NOT a type of epithelial polyp that may occur in the bowel?
Malignant polyps
Which of the following is NOT a contributing factor to the development of colorectal carcinoma?
Epigenetics
Which of the following is NOT a common non-epithelial neoplasm of the large bowel?
Adenocarcinoma
Which of the following is a key factor in the development of colorectal adenocarcinoma?
Familial cancer syndromes
Which pathway is involved in the development of colorectal adenocarcinoma?
APC, p53, KRAS pathway
What is the main purpose of the National Bowel Cancer Screening Program?
To identify patients with cancer or precursor lesions early
What is the precursor lesion in most colorectal carcinomas?
Adenomas
Which of the following is NOT a type of benign epithelial tumor or precursor included in the classification of bowel neoplasms?
Gastrointestinal stromal tumors
Which of the following is classified as a malignant epithelial tumor in the classification of bowel neoplasms?
Medullary adenocarcinoma
Which of the following is NOT a type of mesenchymal tumor included in the classification of bowel neoplasms?
Schwannoma
Which of the following is NOT a type of neuroendocrine tumor included in the classification of bowel neoplasms?
Mucosal melanoma
Which of the following is NOT a type of malignant epithelial tumor included in the classification of bowel neoplasms?
Adenoma
Which of the following locations in the bowel is more likely to have leiomyosarcoma?
Serosa
Which of the following sites in the bowel is more likely to have a higher risk of gastrointestinal stromal tumour?
Submucosa
Which of the following is a risk factor for bowel cancer?
Obesity
What is the most common type of cancer that occurs in the bowel?
Adenocarcinoma
What is the second most common cancer in women?
Bowel cancer
What is the lifetime risk of dying from bowel cancer?
1 in 46
Which of the following is NOT a common type of epithelial polyp that may occur in the bowel?
Malignant polyp
What is the main purpose of the National Bowel Cancer Screening Program?
To detect early signs of colorectal cancer
Which of the following is NOT a contributing factor to the development of colorectal carcinoma?
Epigenetics
Which of the following is NOT a precursor lesion of colon adenocarcinoma?
Lynch syndrome
What is the main pathway involved in the development of colorectal adenocarcinoma?
APC pathway
What is the main purpose of the National Bowel Cancer Screening Program?
To detect and diagnose colorectal adenocarcinoma
Which of the following is NOT a contributing factor to the development of colorectal carcinoma?
Epigenetics
Which of the following is NOT a type of benign epithelial tumor or precursor included in the classification of bowel neoplasms?
Inflammatory myofibroblastic tumor
What is the main purpose of the National Bowel Cancer Screening Program?
To detect and prevent bowel cancer
Which of the following is NOT a type of mesenchymal tumor included in the classification of bowel neoplasms?
Ganglioneuroma
What is the lifetime risk of dying from bowel cancer?
1 in 10
Which of the following is a potential site of origin for tumours in the bowel?
Muscularis
Which of the following is NOT a potential precursor lesion of colon adenocarcinoma?
Carcinoma
Which of the following is a key factor in the development of colorectal adenocarcinoma?
Mitotic activity
Which of the following is NOT a precursor lesion of colon adenocarcinoma?
Familial cancer syndromes
Which of the following is NOT a common risk factor for the development of colorectal carcinoma?
Epigenetics
Which of the following is NOT a common non-epithelial neoplasm of the large bowel?
Leiomyosarcoma
Which of the following is NOT a contributing factor to the development of colorectal carcinoma?
Familial cancer syndromes
Which type of tumour is the most important entity to discuss in the context of colorectal diseases?
Adenocarcinoma
Which of the following is NOT a type of benign epithelial tumor or precursor included in the classification of bowel neoplasms?
Neuroendocrine tumour
Which of the following is NOT a risk factor for developing bowel cancer?
Family history of bowel cancer
What is the most common type of cancer that occurs in the bowel?
Adenocarcinoma
What is the second most common cancer in men?
Colorectal cancer
Which of the following is NOT a type of benign epithelial tumor or precursor included in the classification of bowel neoplasms?
Inflammatory polyp
What is the lifetime risk of dying from bowel cancer?
1 in 46
Which of the following is NOT a type of malignant epithelial tumor included in the classification of bowel neoplasms?
Medullary adenocarcinoma
Which of the following is NOT a type of mesenchymal tumor included in the classification of bowel neoplasms?
Rhabdomyosarcoma
Which of the following is NOT a type of neuroendocrine tumor included in the classification of bowel neoplasms?
PP/PYY-producing tumor
Which of the following is NOT a type of benign epithelial tumor or precursor included in the classification of bowel neoplasms?
Gastrointestinal stromal tumors
Which of the following is a malignant epithelial tumor included in the classification of bowel neoplasms?
Carcinoma
Which of the following is a risk factor for developing bowel cancer?
Smoking
What is the most common type of cancer that occurs in the bowel?
Carcinoma
Which of the following is NOT a potential precursor lesion of colon adenocarcinoma?
Hyperplastic polyps
Which of the following is a descriptive term for a large bowel adenocarcinoma that means 'mushroom-like'?
Villous adenoma
Which site in the bowel is more likely to have low-grade neuroendocrine tumours?
Rectum
Which of the following is NOT a common risk factor for the development of bowel cancer?
Smoking
What is the second most common cancer in men?
Bowel cancer
What is the lifetime risk of dying from bowel cancer?
1 in 46
Which of the following is NOT a type of malignant epithelial tumor included in the classification of bowel neoplasms?
Lymphoma
Which of the following is NOT a contributing factor to the development of colorectal carcinoma?
Familial cancer syndromes
What is the main purpose of the National Bowel Cancer Screening Program?
To detect FOB in asymptomatic individuals
Which of the following is the most common type of epithelial polyp that may occur in the bowel?
Benign polyps
What is the second most common cancer in women?
Colorectal cancer
Which of the following is NOT a type of neuroendocrine tumor included in the classification of bowel neoplasms?
Somatostatin-producing tumor
Which of the following is NOT a type of malignant epithelial tumor included in the classification of bowel neoplasms?
Medullary adenocarcinoma
Which of the following is NOT a type of mesenchymal tumor included in the classification of bowel neoplasms?
Rhabdomyosarcoma
Which of the following is NOT a type of benign epithelial tumor or precursor included in the classification of bowel neoplasms?
Tubulovillous adenocarcinoma
Study Notes
Classification of Bowel Neoplasms (WHO 5th Edition, 2019)
- The classification includes various types of benign and malignant tumors in the bowel.
- Benign epithelial tumors and precursors include hyperplastic polyps, serrated dysplasia, adenomatous polyps, tubular adenomas, villous adenomas, and tubulovillous adenomas.
- Gastrointestinal stromal tumors and adipose tissue and (myo)fibroblastic tumors are also classified.
- Malignant epithelial tumors include adenocarcinoma, adenoma-like adenocarcinoma, micropapillary adenocarcinoma, mucinous adenocarcinoma, poorly cohesive carcinoma, signet ring cell carcinoma, medullary adenocarcinoma, adenosquamous carcinoma, carcinoma with sarcomatoid component, and undifferentiated carcinoma.
- Mesenchymal tumors, such as inflammatory myofibroblastic tumor, desmoid fibromatosis, solitary fibrous tumor, lipoma, inflammatory fibroid polyp, plexiform fibromyxoma, leiomyoma, leiomyosarcoma, rhabdomyosarcoma, haemangioma, and glomus tumor, are also included.
- Neural tumors like schwannoma, granular cell tumor, perineurioma, ganglioneuroma, and ganglioneuromatosis are part of the classification.
- Site-specific hematolymphoid tumors, including MALT lymphoma, duodenal-type follicular lymphoma, enteropathy-associated T-cell lymphoma, and intestinal T-cell lymphoma, are categorized.
- Haematolymphoid tumors occurring with some frequency in the digestive system, such as diffuse large B-cell lymphoma, follicular lymphoma, mantle cell lymphoma, Burkitt lymphoma, plasmablastic lymphoma, and posttransplant lymphoproliferative disorders, are included.
- Neuroendocrine tumors are classified based on grade, including grade 1, grade 2, grade 3, L cell tumor, glucagon-like peptide-producing tumor, PP/PYY-producing tumor, and enterochromaffin cell carcinoid.
- Tumors of uncertain differentiation, such as hematolymphoid tumors, PEComa, synovial sarcoma, and gastrointestinal clear cell sarcoma/malignant gastrointestinal neuroectodermal tumor, are also categorized.
- Other tumors of the digestive system, including mucosal melanoma, serotonin-producing carcinoid, germ cell tumors, neuroendocrine carcinoma, and digestive system metastases, are included.
- The simplified classification of bowel neoplasms includes categories for epithelial tumors (benign and malignant), neuroendocrine tumors, mesenchymal tumors, and others.
Classification of Bowel Neoplasms (WHO 5th Edition, 2019)
- The classification includes various types of benign and malignant tumors in the bowel.
- Benign epithelial tumors and precursors include hyperplastic polyps, serrated dysplasia, adenomatous polyps, tubular adenomas, villous adenomas, and tubulovillous adenomas.
- Gastrointestinal stromal tumors and adipose tissue and (myo)fibroblastic tumors are also classified.
- Malignant epithelial tumors include adenocarcinoma, adenoma-like adenocarcinoma, micropapillary adenocarcinoma, mucinous adenocarcinoma, poorly cohesive carcinoma, signet ring cell carcinoma, medullary adenocarcinoma, adenosquamous carcinoma, carcinoma with sarcomatoid component, and undifferentiated carcinoma.
- Mesenchymal tumors, such as inflammatory myofibroblastic tumor, desmoid fibromatosis, solitary fibrous tumor, lipoma, inflammatory fibroid polyp, plexiform fibromyxoma, leiomyoma, leiomyosarcoma, rhabdomyosarcoma, haemangioma, and glomus tumor, are also included.
- Neural tumors like schwannoma, granular cell tumor, perineurioma, ganglioneuroma, and ganglioneuromatosis are part of the classification.
- Site-specific hematolymphoid tumors, including MALT lymphoma, duodenal-type follicular lymphoma, enteropathy-associated T-cell lymphoma, and intestinal T-cell lymphoma, are categorized.
- Haematolymphoid tumors occurring with some frequency in the digestive system, such as diffuse large B-cell lymphoma, follicular lymphoma, mantle cell lymphoma, Burkitt lymphoma, plasmablastic lymphoma, and posttransplant lymphoproliferative disorders, are included.
- Neuroendocrine tumors are classified based on grade, including grade 1, grade 2, grade 3, L cell tumor, glucagon-like peptide-producing tumor, PP/PYY-producing tumor, and enterochromaffin cell carcinoid.
- Tumors of uncertain differentiation, such as hematolymphoid tumors, PEComa, synovial sarcoma, and gastrointestinal clear cell sarcoma/malignant gastrointestinal neuroectodermal tumor, are also categorized.
- Other tumors of the digestive system, including mucosal melanoma, serotonin-producing carcinoid, germ cell tumors, neuroendocrine carcinoma, and digestive system metastases, are included.
- The simplified classification of bowel neoplasms includes categories for epithelial tumors (benign and malignant), neuroendocrine tumors, mesenchymal tumors, and others.
Classification of Bowel Neoplasms (WHO 5th Edition, 2019)
- The classification includes various types of benign and malignant tumors in the bowel.
- Benign epithelial tumors and precursors include hyperplastic polyps, serrated dysplasia, adenomatous polyps, tubular adenomas, villous adenomas, and tubulovillous adenomas.
- Gastrointestinal stromal tumors and adipose tissue and (myo)fibroblastic tumors are also classified.
- Malignant epithelial tumors include adenocarcinoma, adenoma-like adenocarcinoma, micropapillary adenocarcinoma, mucinous adenocarcinoma, poorly cohesive carcinoma, signet ring cell carcinoma, medullary adenocarcinoma, adenosquamous carcinoma, carcinoma with sarcomatoid component, and undifferentiated carcinoma.
- Mesenchymal tumors, such as inflammatory myofibroblastic tumor, desmoid fibromatosis, solitary fibrous tumor, lipoma, inflammatory fibroid polyp, plexiform fibromyxoma, leiomyoma, leiomyosarcoma, rhabdomyosarcoma, haemangioma, and glomus tumor, are also included.
- Neural tumors like schwannoma, granular cell tumor, perineurioma, ganglioneuroma, and ganglioneuromatosis are part of the classification.
- Site-specific hematolymphoid tumors, including MALT lymphoma, duodenal-type follicular lymphoma, enteropathy-associated T-cell lymphoma, and intestinal T-cell lymphoma, are categorized.
- Haematolymphoid tumors occurring with some frequency in the digestive system, such as diffuse large B-cell lymphoma, follicular lymphoma, mantle cell lymphoma, Burkitt lymphoma, plasmablastic lymphoma, and posttransplant lymphoproliferative disorders, are included.
- Neuroendocrine tumors are classified based on grade, including grade 1, grade 2, grade 3, L cell tumor, glucagon-like peptide-producing tumor, PP/PYY-producing tumor, and enterochromaffin cell carcinoid.
- Tumors of uncertain differentiation, such as hematolymphoid tumors, PEComa, synovial sarcoma, and gastrointestinal clear cell sarcoma/malignant gastrointestinal neuroectodermal tumor, are also categorized.
- Other tumors of the digestive system, including mucosal melanoma, serotonin-producing carcinoid, germ cell tumors, neuroendocrine carcinoma, and digestive system metastases, are included.
- The simplified classification of bowel neoplasms includes categories for epithelial tumors (benign and malignant), neuroendocrine tumors, mesenchymal tumors, and others.
Classification of Bowel Neoplasms (WHO 5th Edition, 2019)
- The classification includes various types of benign and malignant tumors in the bowel.
- Benign epithelial tumors and precursors include hyperplastic polyps, serrated dysplasia, adenomatous polyps, tubular adenomas, villous adenomas, and tubulovillous adenomas.
- Gastrointestinal stromal tumors and adipose tissue and (myo)fibroblastic tumors are also classified.
- Malignant epithelial tumors include adenocarcinoma, adenoma-like adenocarcinoma, micropapillary adenocarcinoma, mucinous adenocarcinoma, poorly cohesive carcinoma, signet ring cell carcinoma, medullary adenocarcinoma, adenosquamous carcinoma, carcinoma with sarcomatoid component, and undifferentiated carcinoma.
- Mesenchymal tumors, such as inflammatory myofibroblastic tumor, desmoid fibromatosis, solitary fibrous tumor, lipoma, inflammatory fibroid polyp, plexiform fibromyxoma, leiomyoma, leiomyosarcoma, rhabdomyosarcoma, haemangioma, and glomus tumor, are also included.
- Neural tumors like schwannoma, granular cell tumor, perineurioma, ganglioneuroma, and ganglioneuromatosis are part of the classification.
- Site-specific hematolymphoid tumors, including MALT lymphoma, duodenal-type follicular lymphoma, enteropathy-associated T-cell lymphoma, and intestinal T-cell lymphoma, are categorized.
- Haematolymphoid tumors occurring with some frequency in the digestive system, such as diffuse large B-cell lymphoma, follicular lymphoma, mantle cell lymphoma, Burkitt lymphoma, plasmablastic lymphoma, and posttransplant lymphoproliferative disorders, are included.
- Neuroendocrine tumors are classified based on grade, including grade 1, grade 2, grade 3, L cell tumor, glucagon-like peptide-producing tumor, PP/PYY-producing tumor, and enterochromaffin cell carcinoid.
- Tumors of uncertain differentiation, such as hematolymphoid tumors, PEComa, synovial sarcoma, and gastrointestinal clear cell sarcoma/malignant gastrointestinal neuroectodermal tumor, are also categorized.
- Other tumors of the digestive system, including mucosal melanoma, serotonin-producing carcinoid, germ cell tumors, neuroendocrine carcinoma, and digestive system metastases, are included.
- The simplified classification of bowel neoplasms includes categories for epithelial tumors (benign and malignant), neuroendocrine tumors, mesenchymal tumors, and others.
Test your knowledge of the Classification of Bowel Neoplasms according to the WHO 5th Edition in this quiz. Explore various types of benign and malignant tumors in the bowel, including epithelial tumors, mesenchymal tumors, neural tumors, hematolymphoid tumors, and more. Expand your understanding of the classification of bowel neoplasms with this informative quiz.
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