Bone Tissue Overview and Functions
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Questions and Answers

What is the primary role of the articular cartilage found at the ends of bones?

  • To serve as a storage area for yellow bone marrow
  • To provide a cushioning effect between articulating bones (correct)
  • To form the periosteum that covers the bone
  • To facilitate the growth of bone during childhood

Which part of a long bone is responsible for growth during childhood and adolescence?

  • Diaphysis
  • Epiphysis
  • Metaphysis (correct)
  • Medullary cavity

Which component of a long bone is primarily involved in nutrient supply and healing post-fracture?

  • Articular cartilage
  • Diaphysis
  • Periosteum (correct)
  • Endosteum

What is contained within the medullary cavity of a long bone?

<p>Yellow bone marrow and blood vessels (D)</p> Signup and view all the answers

Which layer surrounds the bone and is associated with its blood supply?

<p>Periosteum (A)</p> Signup and view all the answers

What is the role of chondroblasts in the development of cartilage?

<p>They secrete the cartilage extracellular matrix. (B)</p> Signup and view all the answers

What is the primary purpose of the perichondrium during cartilage development?

<p>To serve as a mesenchymal covering around the cartilage model. (B)</p> Signup and view all the answers

What occurs during appositional growth of the cartilage model?

<p>New chondroblasts deposit extracellular matrix on the surface. (B)</p> Signup and view all the answers

What triggers the differentiation of osteoprogenitor cells into osteoblasts in the primary ossification center?

<p>Penetration of a nutrient artery into the perichondrium. (B)</p> Signup and view all the answers

Which of the following best describes the primary ossification center (POC)?

<p>It indicates the location where most cartilage is replaced by bone. (C)</p> Signup and view all the answers

What is the primary role of bones in assisting with movement?

<p>Bones provide attachment points for skeletal muscles. (B)</p> Signup and view all the answers

Which function is associated with the storage of essential minerals in bones?

<p>Mineral storage and release (B)</p> Signup and view all the answers

What is the primary function of red bone marrow in the skeletal system?

<p>Produces red and white blood cells. (B)</p> Signup and view all the answers

How many types of bones are categorized in the human skeleton?

<p>5 (B)</p> Signup and view all the answers

What role does the skeleton play in protecting internal organs?

<p>The skeleton surrounds and supports vital organs. (C)</p> Signup and view all the answers

Which of the following types of bones is primarily responsible for storing fat?

<p>Yellow bone marrow in irregular bones (D)</p> Signup and view all the answers

What distinguishes irregular bones from other types of bones in the body?

<p>Their complex shapes and functions (A)</p> Signup and view all the answers

Which component of the skeletal system is primarily involved in the continuous process of rebuilding and breaking down bone?

<p>Bone remodeling (D)</p> Signup and view all the answers

What structures contain osteocytes within compact bone tissue?

<p>Lacunae (C)</p> Signup and view all the answers

What is the primary function of canaliculi in compact bone tissue?

<p>Facilitate communication between osteocytes (B)</p> Signup and view all the answers

Which type of bone tissue is also known as trabecular bone?

<p>Spongy bone (D)</p> Signup and view all the answers

What are the thin columns within spongy bone tissue called?

<p>Trabeculae (B)</p> Signup and view all the answers

Which of the following best describes the process of ossification?

<p>Process of bone formation (A)</p> Signup and view all the answers

During which form of bone formation does bone develop directly from mesenchyme?

<p>Intramembranous ossification (A)</p> Signup and view all the answers

What type of cartilage is involved in endochondral ossification?

<p>Hyaline cartilage (C)</p> Signup and view all the answers

What occurs during the first step of endochondral ossification?

<p>Mesenchymal cells develop into a cartilage model (A)</p> Signup and view all the answers

What process is primarily responsible for creating the medullary cavity?

<p>Osteoclast degradation of spongy bone (C)</p> Signup and view all the answers

Which statement accurately describes secondary ossification centers?

<p>They involve the entry of branches of the epiphyseal artery into epiphyses. (B)</p> Signup and view all the answers

What type of cartilage forms articular cartilage?

<p>Hyaline cartilage (B)</p> Signup and view all the answers

At what stage does the epiphyseal plate continue to function until puberty?

<p>Zone of resting cartilage (A)</p> Signup and view all the answers

What is the primary function of osteoblasts during bone formation?

<p>Building new bone tissue (B)</p> Signup and view all the answers

Which zone of the epiphyseal plate is primarily involved in cartilage growth?

<p>Zone of proliferating cartilage (D)</p> Signup and view all the answers

What triggers the differentiation of osteoprogenitor cells into osteoblasts?

<p>Increase of nutrient arteries (C)</p> Signup and view all the answers

What occurs in the zone of calcified cartilage?

<p>Chondrocytes die as calcification occurs. (A)</p> Signup and view all the answers

What characterizes the zone of proliferating cartilage?

<p>Chondrocytes are arranged like stacks of coins. (A)</p> Signup and view all the answers

In which zone do chondrocytes mature and arrange themselves in columns?

<p>Zone of hypertrophic cartilage (A)</p> Signup and view all the answers

Which process describes bone growth in thickness?

<p>Appositional growth (B)</p> Signup and view all the answers

What is the first step in the process of bone growth in thickness?

<p>Periosteum ridges create grooves for blood vessels. (B)</p> Signup and view all the answers

Which cell type is responsible for breaking down bone?

<p>Osteoclasts (C)</p> Signup and view all the answers

What is produced as a result of osteoblasts replacing cartilage?

<p>Bone extracellular matrix (A)</p> Signup and view all the answers

What type of bone growth occurs through the differentiation of mesenchymal cells into osteoblasts?

<p>Intramembranous ossification (D)</p> Signup and view all the answers

Flashcards

What is unique about bone tissue?

Bone is a dynamic tissue that does more than just support and anchor muscles. It's constantly being remodeled, building new bone while breaking down old bone.

What does the skeletal system consist of?

The skeletal system is the complete framework of bones and their associated cartilages.

What is osteology?

Osteology is the study of bone structure and treatment of bone disorders.

What is bone tissue made of?

Bone, or osseous tissue, is composed of various tissues working together.

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What is the main function of the skeleton?

The skeleton serves as the structural framework of the body, providing support.

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What other important function does the skeleton have?

The skeleton protects vital internal organs from injury.

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How does the skeleton help with movement?

Skeletal muscles attach to bones, and their contractions allow for movement.

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What is one of the key roles bones play in mineral metabolism?

Bones store and release minerals, particularly calcium and phosphorus, essential for body functions.

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Diaphysis

The main shaft or central part of a long bone.

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Epiphysis

The ends of a long bone, responsible for joint formation.

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Metaphysis

Regions between the diaphysis and epiphysis, containing the growth plate in growing bones.

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Articular Cartilage

A thin layer of hyaline cartilage covering the epiphysis, which helps reduce friction and absorb shock during movement.

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Periosteum

The tough outer membrane of bone that provides blood supply, helps in fracture repair, and serves as an attachment point for tendons and ligaments.

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Canaliculi

Small channels radiating from lacunae in bone tissue.

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Lacunae in Bone

Spaces within bone tissue that house osteocytes.

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Osteocytes

Mature bone cells responsible for maintaining the bone matrix.

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Spongy Bone

Internal layer of bone, often referred to as trabecular bone.

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Trabeculae

Thin columns of bone that make up spongy bone.

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Ossification

Process of bone formation; can happen in two ways, intramembranous or endochondral.

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Intramembranous Ossification

Bone formation directly from mesenchymal cells, typical for flat bones.

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Endochondral Ossification

Bone formation within a pre-existing hyaline cartilage model, used for most bones.

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Zone of proliferating cartilage

The region of cartilage where chondrocytes divide and create new cartilage, allowing the bone to grow in length.

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Chondrocytes

Cartilage cells that are responsible for creating and maintaining cartilage tissue.

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Zone of hypertrophic cartilage

Zone where large, mature chondrocytes align in columns, contributing to the length increase of the bone.

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Zone of calcified cartilage

The zone where chondrocytes have died and the cartilage matrix has hardened (calcified), preparing the bone for replacement by real bone tissue.

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Appositional growth

The process by which bones grow in width or thickness, involving the formation of new bone tissue on the outer surface.

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Osteoclasts

Cells that break down bone tissue, essential for bone remodeling and calcium release.

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Osteoblasts

Cells that build new bone tissue by secreting collagen and other matrix components.

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What are chondrocytes?

Specialized cells embedded in cartilage extracellular matrix.

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What is interstitial growth?

Growth of cartilage model in length, due to chondrocytes dividing.

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What is appositional growth?

Increase in thickness of cartilage model, due to new chondroblasts from the perichondrium depositing matrix.

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What happens to the cartilage matrix during endochondral ossification?

The process where the inner cartilage matrix calcifies, causing chondrocytes to die due to lack of nutrients.

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What is a primary ossification center?

The formation of bone tissue on the diaphysis, replacing most of the cartilage.

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What is endochondral ossification?

The formation of bone from hyaline cartilage model.

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What is the medullary cavity?

A cavity within the diaphysis of a long bone that contains bone marrow.

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What are osteoclasts?

Specialized cells that break down bone tissue, responsible for the formation of the medullary cavity.

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What is secondary ossification?

The process of bone formation in the epiphyses of long bones, resulting in secondary ossification centers.

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What is articular cartilage?

A layer of hyaline cartilage that covers the epiphysis, responsible for smooth joint articulation.

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What is the epiphyseal plate?

The region of hyaline cartilage between the diaphysis and epiphysis, responsible for longitudinal bone growth.

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How does bone growth in length occur?

Bone growth in length occurs by growth of cartilage on the epiphyseal side of the epiphyseal plate and its replacement by bone on the diaphyseal side.

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What is the zone of resting cartilage?

The zone of the epiphyseal plate where chondrocytes are inactive and anchor the plate to the epiphysis.

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Study Notes

Bone Tissue Overview

  • Bone is more than just support; it also remodels continuously, building new bone and breaking down old bone.
  • The skeletal system includes the bones and their cartilages.
  • Osteology studies bone structure and disorders.

Functions of Bones

  • Support: The skeleton forms the body's framework.
  • Protection: Bones shield vital organs from injury.
  • Movement: Skeletal muscles attach to bones, and their contraction causes movement.
  • Mineral storage and release: Bones store calcium and phosphorus, essential for bodily functions. Ninety-nine percent of the body's total calcium is stored in bones.
  • Blood cell production: Red bone marrow—a connective tissue—produces red blood cells, white blood cells, and platelets. Red bone marrow produces two million red blood cells per second.
  • Triglyceride storage: Yellow bone marrow, made of fat cells, stores triglycerides (energy).

Types of Bones

  • There are 206 bones in an adult skeleton
  • Five types: long, short, flat, irregular, and sesamoid

Anatomy of a Bone

  • Diaphysis: The bone's shaft or body.
  • Epiphysis: The proximal and distal ends of the bone.
  • Metaphysis: The regions between the diaphysis and epiphysis. In growing bones, the metaphysis contains the epiphyseal plate (growth plate).
  • Articular cartilage: Covers the epiphysis; reduces friction during joint movement.
  • Periosteum: Tough connective tissue; nourishes bone, assists in fracture repair, and provides attachment points for tendons and ligaments.
  • Medullary cavity: The marrow cavity; contains yellow bone marrow in adults.
  • Endosteum: Thin membrane lining the medullary cavity.

Histology of Bone

  • Bone cells: Osteocytes, osteoblasts, osteoclasts, and osteoprogenitors
  • Compact bone: Dense outer layer; composed of repeating structural units called osteons.
  • Spongy bone: Located in the interior of bones; referred to as trabecular bone tissue; consists of trabeculae (thin columns) made of lamellae; Red and yellow bone marrow fill the spaces between trabeculae.

Bone Formation

  • Osteogenesis (ossification): The process of bone formation.
  • Two methods: Intramembranous and endochondral ossification.
  • Intramembranous ossification: Forms flat bones directly from mesenchyme.
  • Endochondral ossification: Forms most bones from hyaline cartilage
  • Bone growth in length: Cartilage growth within the epiphyseal plate is replaced by osseous tissue.
    • Zone of resting cartilage: Anchors the epiphyseal plate to the epiphysis.
    • Zone of proliferating cartilage: Chondrocytes multiply and arrange themselves like stacks of coins.
    • Zone of hypertrophic cartilage: Chondrocytes mature and enlarge.
    • Zone of calcified cartilage: Chondrocytes die, and the matrix calcifies.
  • Bone growth in thickness (appositional growth): The periosteum forms new bone on the outer surface, increasing bone diameter.

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Description

Explore the essential functions of bone tissue, including support, protection, and mineral storage. Learn about the different types of bones and the role of osteology in understanding bone structure and disorders. This quiz covers the significant aspects of the skeletal system and its continuous remodeling.

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