Bone Tissue and Structure
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Questions and Answers

During endochondral ossification, what specific tissue is replaced by bone?

  • Hyaline cartilage (correct)
  • Fibrocartilage
  • Elastic cartilage
  • Connective tissue membranes

Which of the following best describes the role of canaliculi in bone tissue?

  • They provide a pathway for blood vessels to enter the bone.
  • They form the central canal of an osteon.
  • They house osteocytes within the bone matrix.
  • They facilitate communication and nutrient exchange between osteocytes. (correct)

What is the primary reason longitudinal bone growth ceases after puberty?

  • The epiphyseal plate ossifies and becomes the epiphyseal line. (correct)
  • The yellow bone marrow expands and inhibits growth.
  • The bone has reached its genetically determined length.
  • Increased levels of calcium inhibit chondrocyte activity.

A patient is diagnosed with osteopenia. This condition is most directly related to a deficiency in which component of bone?

<p>Calcium phosphate (hydroxyapatite) (A)</p> Signup and view all the answers

Which of the following sequences accurately describes the typical order of events in bone fracture repair?

<p>Hematoma formation → fibrocartilage callus formation → bony callus formation → bone remodeling (B)</p> Signup and view all the answers

Which of the following correctly identifies the membrane covering the outer surface of long bones and the membrane lining the medullary cavity?

<p>Periosteum; Endosteum (C)</p> Signup and view all the answers

Which of the following best describes a foramen?

<p>A round or oval opening through a bone. (B)</p> Signup and view all the answers

During long bone formation, what crucial event occurs at the epiphyseal plate that contributes to bone lengthening?

<p>Chondrocytes proliferate and arrange themselves into a column-like structure, followed by ossification of the cartilage matrix. (D)</p> Signup and view all the answers

How do the diaphysis and epiphysis relate to a long bone's structure?

<p>Diaphysis is the shaft, epiphysis is the expanded end. (B)</p> Signup and view all the answers

What best describes how bones respond to long-term mechanical stress, according to Wolff's Law?

<p>Bones adapt their internal architecture, mass and external structure to withstand applied stresses. (C)</p> Signup and view all the answers

Which of the following best represents the order of events in the repair of a fractured bone?

<p>Hematoma formation → fibrocartilaginous callus formation → bony callus formation → bone remodeling (D)</p> Signup and view all the answers

How do hyaline, elastic, and fibrocartilage differ in function and location?

<p>Hyaline is most abundant; elastic is in the ear; fibrocartilage resists compression. (C)</p> Signup and view all the answers

What is the correct sequence of events in bone fracture repair?

<p>Fracture hematoma formation, fibrocartilaginous callus formation, bony callus formation, bone remodeling (A)</p> Signup and view all the answers

How does parathyroid hormone (PTH) influence bone remodeling in response to decreased blood calcium levels?

<p>PTH stimulates osteoclast activity, leading to bone resorption and the release of calcium into the bloodstream. (C)</p> Signup and view all the answers

What key characteristics differentiate osteoporosis from osteomalacia?

<p>Osteoporosis involves reduced bone mass; osteomalacia involves painful fractures. (B)</p> Signup and view all the answers

What is the primary distinction between osteomalacia and rickets in terms of who is affected?

<p>Osteomalacia affects adults, while rickets affects children. (C)</p> Signup and view all the answers

Which of the following is NOT a primary function of the skeletal system?

<p>Regulation of blood glucose levels through hormone secretion. (B)</p> Signup and view all the answers

Which of the following best describes the anatomical structure referred to as a 'tubercle' in bone anatomy?

<p>A bony expansion carried on a narrow neck (D)</p> Signup and view all the answers

Which cellular component is directly responsible for the formation of bone matrix?

<p>Osteoblast (B)</p> Signup and view all the answers

Which structural feature is characteristic of compact bone but not of spongy bone?

<p>Osteons (D)</p> Signup and view all the answers

During endochondral ossification, what roles do the primary and secondary ossification centers play in long bone development?

<p>The primary center forms the diaphysis; the secondary center forms the epiphyses. (D)</p> Signup and view all the answers

A bone is classified as a long bone if its length is:

<p>Greater in length than width. (A)</p> Signup and view all the answers

Which tissue type is NOT a primary component of bone organs?

<p>Adipose tissue. (A)</p> Signup and view all the answers

Where does hematopoiesis primarily occur in adults?

<p>Red bone marrow in spongy bone (A)</p> Signup and view all the answers

What is the primary structural difference between compact and spongy bone?

<p>The organization of osteons. (D)</p> Signup and view all the answers

Which of the following best describes the function of the epiphyseal plate?

<p>It allows for bone growth in length. (D)</p> Signup and view all the answers

The periosteum is secured to the underlying bone via:

<p>Sharpey's fibers. (D)</p> Signup and view all the answers

Which of the following is true regarding bone markings?

<p>They serve as sites for muscle attachment and joint formation. (B)</p> Signup and view all the answers

How do osteoblasts and osteoclasts work together to maintain bone homeostasis?

<p>Osteoblasts deposit bone matrix, while osteoclasts resorb bone matrix. (C)</p> Signup and view all the answers

Flashcards

Bone Shape Categories

Bones classified by their shape, such as long, short, flat, irregular, and sesamoid.

Functions of Bones

Support, protection, movement, mineral storage, blood cell formation, triglyceride storage, and hormone production.

Compact Bone

Dense outer layer of bone.

Spongy Bone

Internal layer of bone with trabeculae.

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Diaphysis

Shaft of a long bone.

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Epiphysis

Ends of a long bone.

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Cartilage

Hyaline cartilage providing support and flexibility to structures.

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Osteocytes

Mature bone cells. Monitor and maintain bone matrix.

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Periosteum

The outer fibrous connective tissue membrane on long bones.

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Endosteum

Connective tissue membrane lining the medullary cavity.

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Trochanter

A large, blunt, irregularly shaped bony projection.

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Foramen

A round or oval opening through a bone.

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Facet

A smooth, nearly flat articular (joint) surface.

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Head

A bony expansion carried on a narrow neck.

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How do bones thicken?

Bone thickening occurs through appositional growth, adding new layers to the outer surface.

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How do Bones Lengthen?

Bones lengthen at the epiphyseal plate, where cartilage cells divide and are replaced by bone.

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Epiphyseal Plate to Line

The epiphyseal plate is a layer of hyaline cartilage in the metaphysis of a growing bone. It becomes the epiphyseal line when bone growth stops and the cartilage is replaced by bone.

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Bone Response to Stress

Bones respond to mechanical stress by increasing bone density and strength in areas subjected to higher stress.

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Wolff's Law

Wolff's Law states that bone adapts to the loads placed upon it. Factors affecting remodeling include hormones and nutrient availability.

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Fossa

A shallow, basinlike depression in a bone, often serving as an articular surface.

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Hematopoiesis

Hematopoiesis is the formation of blood cells within the red marrow cavities of certain bones. In newborns, most bones contain red bone marrow.

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Bone Cells

Osteoblast (bone-forming), Osteocyte (mature bone), Osteoclast (bone-destroying), Osteogenic cell (bone stem cell).

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Bone Composition

Major inorganic minerals in bone's intercellular matrix; collagen is the major organic fiber.

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Osteogenesis

Bone formation via connective tissue membranes or hyaline cartilage replacement.

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Intramembranous Ossification

Process where connective tissue membranes are replaced with bony tissue.

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Endochondral Ossification

Process where hyaline cartilage is replaced with bony tissue.

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Yellow Bone Marrow

Replaces red marrow in the diaphysis of long bones in adults to keep bones light.

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Study Notes

  • A shallow, basinlike depression in a bone, often serving as an articular surface, is a fossa.
  • Hematopoiesis is the formation of blood cells within the red marrow cavities of certain bones like spongy bone.
  • In newborn infants, nearly all flat and long bones contain red bone marrow.
  • Osteoblasts are bone-forming cells.
  • Osteocytes are mature bone cells.
  • Osteoclasts are bone-destroying cells.
  • Osteoprogenitor (osteogenic) cells are bone stem cells.
  • The basic functional unit of compact bone is the osteon with rings of bone matrix called lamellae.
  • The epiphyseal plate is composed of hyaline cartilage and functions as the longitudinal growth region of the long bone.
  • A spine is a sharp, slender, often pointed projection.
  • Lacunae are cavities in bone where bone cells live.
  • Canaliculi are narrow passageways that contain cytoplasmic extensions of osteocytes for passage of nutrients and wastes.
  • The fibrous connective tissue membrane that covers the outer surface of long bone is called the periosteum, and the endosteum is the connective tissue membrane that lines the medullary cavity, a hollow space in the shaft of a long bone.
  • A trochanter is a very large, blunt, irregularly shaped process.
  • A foramen is a round or oval opening through a bone.
  • The diaphysis is the shaft of a long bone.
  • The epiphysis is the expanded portion of the long bone at its ends.
  • Hyaline cartilage is the most abundant skeletal cartilage.
  • Fibrocartilage is able to withstand large amounts of compression.
  • Elastic cartilage is located in the external ear and epiglottis.
  • The first stage of bone repair is hematoma formation.
  • Hematoma formation is caused by tearing of blood vessels in and around the fracture site.
  • Fibrocartilage callus follows the hematoma formation.
  • Fibrocartilage callus is caused by the activity of fibroblasts and osteoblasts to create an overgrown splint around the fracture site.
  • Bony callus formation occurs after fibrocartilage callus.
  • During bony callus formation, trabeculae invade the callus and begin to replace fibrous tissue.
  • Bone remodeling is the final step in bone repair.
  • Bone remodeling removes excess bony material from the external and internal surfaces of the diaphysis.
  • Osteopenia is a condition that occurs with aging that causes a gradual reduction in bone mass.
  • Osteoporosis is a painful condition that occurs when the bones become weak and thin and tend to fracture easily.
  • A head is a bony expansion carried on a narrow neck.
  • In endochondral ossification, the diaphysis is the primary ossification center.
  • In endochondral ossification, the epiphysis is the secondary ossification center, and the epiphyseal plate is the site of length increase in long bones.
  • A facet is a smooth, nearly flat articular surface.
  • Calcium phosphate (hydroxyapatite) are the major inorganic minerals contained in the intercellular matrix of bone.
  • Collagen is the major organic fiber of bone.
  • Osteogenesis, intramembranous ossification, and endochondral ossification are the processes of bone formation.
  • Osteogenesis is accomplished by either replacement of connective tissue membranes with bony tissue.
  • Intramembranous ossification is the replacement of connective tissue membranes with bony tissue.
  • Endochondral ossification is the replacement of hyaline cartilage with bony tissue.
  • Yellow bone marrow is found in the hollow interior of the diaphyseal portion of adult long bones, and the large marrow cavities keep the weight of the bones light.
  • Longitudinal bone growth ends after puberty because the epiphyseal plate of cartilage is ossified into the epiphyseal line.

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Description

Understanding bone tissue involves knowing its varied structures and cell types. Bones have shallow depressions called fossae. Red marrow is where blood cells form. Bones are made of osteoblasts, osteocytes, and osteoclasts.

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