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Questions and Answers
What is the primary function of osteoblasts?
What is the primary function of osteoblasts?
- They regulate calcium levels in the blood.
- They synthesize and mineralize the bone matrix. (correct)
- They signal the body to produce more red blood cells.
- They maintain bone density.
What triggers the multiplication of osteogenic cells into osteoblasts?
What triggers the multiplication of osteogenic cells into osteoblasts?
- Mechanical stress applied to the bone. (correct)
- Increased blood flow to the bone.
- The presence of vitamin D in the diet.
- The intake of calcium supplements.
Where do osteocytes reside within the bone structure?
Where do osteocytes reside within the bone structure?
- In lacunae. (correct)
- In the central canal of osteons.
- Along the endosteum surface.
- Inside the periosteum layer.
What is the role of canaliculi in bone tissue?
What is the role of canaliculi in bone tissue?
How do osteocytes function in relation to mechanical stress?
How do osteocytes function in relation to mechanical stress?
What percentage of bone is composed of organic matter?
What percentage of bone is composed of organic matter?
Which component allows bones to support body weight without sagging?
Which component allows bones to support body weight without sagging?
What is the main inorganic component of bone?
What is the main inorganic component of bone?
Which of the following describes the polymer portion of bone?
Which of the following describes the polymer portion of bone?
How is organic matter in bone primarily synthesized?
How is organic matter in bone primarily synthesized?
What role does collagen play in bone structure?
What role does collagen play in bone structure?
Which of the following components are considered part of the ceramic portion of bone?
Which of the following components are considered part of the ceramic portion of bone?
What is the overall structure of bone classified as?
What is the overall structure of bone classified as?
What is the primary function of the epiphyseal plate in children’s bones?
What is the primary function of the epiphyseal plate in children’s bones?
Which structure is primarily responsible for the entry of blood vessels into the bone?
Which structure is primarily responsible for the entry of blood vessels into the bone?
What is found at the inner edge of a bone surrounding the marrow canal?
What is found at the inner edge of a bone surrounding the marrow canal?
Which part of the bone is primarily associated with muscle attachment and protection?
Which part of the bone is primarily associated with muscle attachment and protection?
What type of cartilage covers the joint surface for easier movement?
What type of cartilage covers the joint surface for easier movement?
Which type of cells are primarily located within the osteogenic layer of the periosteum?
Which type of cells are primarily located within the osteogenic layer of the periosteum?
What marks the transition from growth in length to the end of bone growth in adults?
What marks the transition from growth in length to the end of bone growth in adults?
Which structure actively participates in bone remodeling by dissolving osseous tissue?
Which structure actively participates in bone remodeling by dissolving osseous tissue?
What is one of the primary functions of the skeletal system?
What is one of the primary functions of the skeletal system?
Which of the following best describes the process of mineralization in bone development?
Which of the following best describes the process of mineralization in bone development?
What tissue types are found within an individual bone?
What tissue types are found within an individual bone?
Which component of long bone is important for providing leverage?
Which component of long bone is important for providing leverage?
What is the main purpose of red bone marrow?
What is the main purpose of red bone marrow?
What distinguishes compact bone from spongy bone?
What distinguishes compact bone from spongy bone?
Which of the following is NOT a major function of the skeletal system?
Which of the following is NOT a major function of the skeletal system?
Which part of a long bone helps protect the ends of the bone and facilitates joint movement?
Which part of a long bone helps protect the ends of the bone and facilitates joint movement?
What hormone is secreted by osteocytes and osteoblasts?
What hormone is secreted by osteocytes and osteoblasts?
How does osteocalcin affect insulin secretion?
How does osteocalcin affect insulin secretion?
Which of the following effects does insulin have on adipose tissue?
Which of the following effects does insulin have on adipose tissue?
What is one way that insulin lowers plasma fatty acid levels?
What is one way that insulin lowers plasma fatty acid levels?
How does osteocalcin influence male fertility?
How does osteocalcin influence male fertility?
What physiological states can lead to increased levels of osteocalcin?
What physiological states can lead to increased levels of osteocalcin?
Which of the following statements is true regarding osteocalcin-deficient mice?
Which of the following statements is true regarding osteocalcin-deficient mice?
What aspect of glucose metabolism is promoted by osteocalcin?
What aspect of glucose metabolism is promoted by osteocalcin?
Study Notes
Bone Structure and Composition
- Bone is a composed of 33% organic matter and 66% inorganic matter
- The organic matter is synthesized by osteoblasts and made up of collagen, carbohydrate–protein complexes, glycosaminoglycans, proteoglycans, and glycoproteins
- The inorganic matter is predominantly calcium and phosphate salts which form the ceramic portion of bone and contribute to its strength and ability to support weight
- The collagen component of bone provides flexibility
- The combination of ceramic and polymer components gives bone its unique structural properties
Types of Bone Tissue
- Compact bone forms the dense outer shell of bone
- Spongy or cancellous bone is loosely organized and has a lattice-like structure
- Bone marrow is found in the medullary cavity of long bones
General Features of Long Bones
- Long bones have a diaphysis (shaft) and epiphyses (ends)
- The epiphyseal plate is made of hyaline cartilage and allows for longitudinal bone growth in children
- Articular cartilage is smooth hyaline cartilage that covers joint surfaces, facilitating movement
- Nutrient foramina are tiny holes in the bone surface that allow blood vessels to penetrate
- Periosteum is the outer sheath of bone that contains fibrous collagen and osteogenic cells which are important for growth and healing
- Endosteum lines the marrow cavity and houses cells that dissolve and deposit osseous tissue
Bone Cells
- Osteoblasts are bone-forming cells responsible for osteogenesis
- Osteocytes are mature osteoblasts that become trapped in the matrix they deposited
- Osteoclasts are responsible for the resorption or breakdown of bone tissue
Osteocalcin
- Osteocalcin is a hormone secreted by osteoblasts and osteocytes
- Osteocalcin has various physiological effects including stimulation of insulin secretion by the pancreas, promotion of male fertility, promotion of glucose metabolism and energy utilization, and inhibition of parasympathetic innervation during stressful situations
- Research has shown that osteocalcin-deficient mice exhibit increased anxiety, decreased memory, and a more passive behavior
Functions of Bone and the Skeletal System
- Support: Bones provide structural support for the body, including limbs and vertebrae, and support for teeth and viscera
- Protection: Bones protect vital organs such as the brain, spinal cord, heart, and lungs
- Movement: Bones enable movement through muscle attachments and joint articulation
- Electrolyte Balance: Bones regulate blood calcium and phosphate levels
- Acid-Base Balance: Bones play a role in buffering blood pH changes
- Blood Formation: Red bone marrow, found in the medullary cavity, is the primary site of blood cell production
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Description
Explore the fundamental aspects of bone structure and composition, including organic and inorganic components. Understand the differences between compact and spongy bone tissue, and learn about the general features of long bones, including their growth patterns. This quiz is essential for students studying biology or anatomy.
