Bone Metabolism and Osteoporosis Quiz

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10 Questions

What is the primary organic component of bone matrix?

Collagen type I

In what form is the majority of calcium stored in the skeleton?

Hydroxyapatite

What type of cells do not develop into osteoclasts in cell cultures unless there are osteoblasts or similar cells?

Monocyte/macrophage lineage

What is the primary function of osteoblasts?

Bone formation

What is the main role of mesenchymal stem cells in bone metabolism?

Differentiation into osteoblasts

What is the primary inorganic component of bone matrix?

Calcium (Ca++)

Which cells are essential for the development of osteoclasts in cell cultures?

Osteoblasts

What type of cells are derived from mesenchymal stem cells in bone metabolism?

Osteoblasts

What is the main function of osteocytes in bone metabolism?

Regulate mineral homeostasis

Which cells are responsible for the majority of collagen production in bone matrix?

Osteoblasts

Test your knowledge of bone metabolism and osteoporosis with this quiz by Tammy L. Dela Rosa, MD, MMedSc. Learn about the functions of bone cells, osteoclastogenesis, calcium metabolism and regulation, pathologic conditions, osteoporosis, treatment strategies, and diagnostic tools like DEXA, FRAX, and OSTA.

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