Questions and Answers
What is the main function of bone marrow?
To produce blood cells
What is the composition of bone marrow?
70% hematopoietic stem cells, 30% stromal cells
What is the process of producing red blood cells?
Erythropoiesis
What type of stem cell can differentiate into different blood cell types?
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What is the name of the process of blood cell formation and development?
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What is the name of the type of bone marrow found in compact bones?
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What is a treatment for certain blood disorders and cancers?
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Study Notes
Function
- Produces blood cells: red blood cells, white blood cells, and platelets
- Responsible for hematopoiesis: the process of blood cell formation and development
Structure
- Spongy, fatty tissue found in the cavities of bones
- Divided into two types:
- Red bone marrow: found in spongy bones, responsible for hematopoiesis
- Yellow bone marrow: found in compact bones, composed mostly of fat cells
Composition
- 70% of bone marrow is composed of hematopoietic stem cells and their progeny
- 30% is composed of stromal cells: fat cells, reticular cells, and osteoblasts
Stem Cells
- Hematopoietic stem cells: capable of differentiating into different blood cell types
- Mesenchymal stem cells: capable of differentiating into stromal cells
Blood Cell Production
- Erythropoiesis: production of red blood cells
- Granulopoiesis: production of white blood cells (granulocytes)
- Thrombopoiesis: production of platelets
Clinical Significance
- Bone marrow disorders: anemia, leukemia, lymphoma, and multiple myeloma
- Bone marrow transplantation: a treatment for certain blood disorders and cancers
Function of Bone Marrow
- Produces blood cells: red blood cells, white blood cells, and platelets
- Responsible for hematopoiesis, the process of blood cell formation and development
Structure of Bone Marrow
- Spongy, fatty tissue found in the cavities of bones
- Divided into two types: red bone marrow and yellow bone marrow
- Red bone marrow: found in spongy bones, responsible for hematopoiesis
- Yellow bone marrow: found in compact bones, composed mostly of fat cells
Composition of Bone Marrow
- 70% composed of hematopoietic stem cells and their progeny
- 30% composed of stromal cells: fat cells, reticular cells, and osteoblasts
Types of Stem Cells
- Hematopoietic stem cells: capable of differentiating into different blood cell types
- Mesenchymal stem cells: capable of differentiating into stromal cells
Blood Cell Production Process
- Erythropoiesis: production of red blood cells
- Granulopoiesis: production of white blood cells (granulocytes)
- Thrombopoiesis: production of platelets
Clinical Significance of Bone Marrow
- Bone marrow disorders: anemia, leukemia, lymphoma, and multiple myeloma
- Bone marrow transplantation: a treatment for certain blood disorders and cancers
