Bone Health and Aging

Questions and Answers

Inability to move

Mobility

Immobilization

Improved mobility leads to improved perfusion and gas exchange Signup and view all the answers

Osteogenic cells, osteoblasts, osteoclasts, and osteocytes Signup and view all the answers

Bone strength Signup and view all the answers

Low bone density and increased risk of fracture Signup and view all the answers

Parathyroid hormone Signup and view all the answers

Hip, distal radius, and vertebrae Signup and view all the answers

Estrogens and androgens Signup and view all the answers

Compact bone (cortical) and spongy bone (trabecular) Signup and view all the answers

Genetics, sex, puberty, and lifestyle factors Signup and view all the answers

High turnover and remodeling imbalance Signup and view all the answers

Low calcium or Vit D Signup and view all the answers

Nail growth Signup and view all the answers

Bone remodeling Signup and view all the answers

Study Notes

Aging and Osteoporosis: Risk Factors and Conditions

Age-related changes can lead to falls, fractures, and loss of mobility
Factors critical for healthy aging include bone strength, muscle strength, joint health, neurological function, and nutrition
Bone tissue is composed of compact bone (cortical) and spongy bone (trabecular)
Bone tissue cell types include osteogenic cells, osteoblasts, osteoclasts, and osteocytes
Bone remodeling is a dynamic process crucial for maintaining, repairing, and adapting bone
Osteoporosis is characterized by low bone density and increased risk of fracture
Osteoporosis is more prevalent in women, with risk factors including age, low calcium or Vit D, genetics, hormone imbalance, race, and medications
Peak bone mass is influenced by genetics, sex, puberty, and lifestyle factors
Calcium homeostasis is regulated by parathyroid hormone and activated vitamin D
Estrogens and androgens play essential roles in bone growth and remodeling
Osteoporosis pathogenesis involves high turnover and remodeling imbalance, affecting both spongy and compact bone
Clinical manifestations of osteoporosis include fractures, pain, deformity, and additional falls, with common fracture sites being the hip, distal radius, and vertebrae