Body Weight and Energy Balance
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Questions and Answers

What percentage of body fat is present in a newborn?

  • 19%
  • 14% (correct)
  • 10%
  • 28%
  • What is the primary method used in Bioelectrical Impedance devices to determine body fat percentage?

  • Sending an electrical signal through the body (correct)
  • Measuring body density
  • Analyzing body water composition
  • Measuring mid-arm circumference
  • What is the primary purpose of skinfold measurements?

  • To determine total body potassium
  • To measure body density
  • To measure mid-arm circumference
  • To estimate body fat percentage (correct)
  • What is the typical body fat percentage of a female adult?

    <p>28%</p> Signup and view all the answers

    Which of the following is NOT a method of measuring body composition?

    <p>Ultracentrifugation</p> Signup and view all the answers

    What is the body fat percentage of an obese male adult?

    <p>28%</p> Signup and view all the answers

    What is the primary principle of air displacement plethysmography in measuring body composition?

    <p>Measuring the volume of the chamber with and without the subject to calculate body density</p> Signup and view all the answers

    What is the energy density of protein in kilojoules per gram?

    <p>22.7 kj/g</p> Signup and view all the answers

    What percentage of energy from food is lost as heat?

    <p>50%</p> Signup and view all the answers

    What is the energy requirement of an infant in the first year, compared to an adult?

    <p>Twice the energy requirement of an adult</p> Signup and view all the answers

    What is the approximate energy expenditure of an individual playing football, compared to their basal metabolic rate?

    <p>7 times the basal metabolic rate</p> Signup and view all the answers

    What is the energy density of fat in kilocalories per gram?

    <p>9.2 kcal/g</p> Signup and view all the answers

    What is the approximate energy requirement during lactation?

    <p>2 MJ or 500 kcal/day</p> Signup and view all the answers

    What is the part of the brain that regulates energy intake?

    <p>Hypothalamus</p> Signup and view all the answers

    According to the Finnish study, which of the following is a risk factor for obesity?

    <p>Little physical activity</p> Signup and view all the answers

    Which of the following conditions is associated with obesity?

    <p>Hypertension</p> Signup and view all the answers

    What is the relative risk of myocardial infarction associated with obesity?

    <p>1.9</p> Signup and view all the answers

    Which of the following diets is primarily used to reduce the frequency of epileptic seizures in children?

    <p>Keto diet</p> Signup and view all the answers

    What is the effect of starvation on metabolic rate?

    <p>It decreases by 15-30%</p> Signup and view all the answers

    Why are high protein diets often easier to follow?

    <p>Because of their satiety value of protein</p> Signup and view all the answers

    What is the primary concern with keto diets?

    <p>High saturated fat content</p> Signup and view all the answers

    What is the outcome of intermittent fasting compared to continuous calorie restriction?

    <p>It has the same outcome as continuous calorie restriction</p> Signup and view all the answers

    What is the primary function of leptin in regulating hunger and satiety?

    <p>To signal the state of the fat stores</p> Signup and view all the answers

    Which of the following neurotransmitters is involved in stimulating hunger pathways?

    <p>Neuropeptide Y (NPY)</p> Signup and view all the answers

    What is the primary function of insulin in regulating hunger and satiety?

    <p>To signal the fullness of carbohydrate stores</p> Signup and view all the answers

    Which of the following is NOT a short-term signal involved in regulating hunger and satiety?

    <p>Leptin</p> Signup and view all the answers

    What is the primary function of PYY 3-36 in regulating hunger and satiety?

    <p>To suppress appetite</p> Signup and view all the answers

    Which of the following is involved in integrating hunger and satiety signals in the hypothalamus?

    <p>The arcuate nucleus</p> Signup and view all the answers

    What is the primary function of AgRP in regulating hunger and satiety?

    <p>To block the action of melanocortin peptides</p> Signup and view all the answers

    What determines the last spoonful of food?

    <p>Short-term signals from the GI tract</p> Signup and view all the answers

    What is the basal metabolic rate of a moderately obese person in MJ/day?

    <p>7.6</p> Signup and view all the answers

    Which of the following is a socio-economic factor contributing to obesity?

    <p>Lower socio-economic class in the UK</p> Signup and view all the answers

    What is the primary cause of obesity in endocrinological factors?

    <p>Adrenal hyperactivity</p> Signup and view all the answers

    What is the percentage decrease in energy expenditure by children compared to 25 years ago?

    <p>65%</p> Signup and view all the answers

    What is the function of propionate produced by certain gut microbes?

    <p>Decreases appetite</p> Signup and view all the answers

    What is the effect of having 2 copies of the FTO gene on body weight?

    <p>3 kg heavier</p> Signup and view all the answers

    What is the characteristic of individuals with 'high-risk' FTO genotypes?

    <p>Preference for high-fat foods and reduced satiety responsiveness</p> Signup and view all the answers

    What is the enzyme encoded by the FTO gene?

    <p>2 oxoglutarate dependent dioxygenase</p> Signup and view all the answers

    Study Notes

    Body Composition

    • Body composition is measured using various methods, including:
      • Body density
      • Body water
      • Total body potassium (K)
      • Methyl histidine or creatinine excretion
      • Skinfold measurements (biceps, triceps, supra iliac, subscapular)
      • Mid-arm circumference
      • Bioelectrical impedance
      • Air displacement plethysmography (Bod Pod)
    • Newborns have 14% body fat, while adults have around 15-28% body fat
    • Obese males have around 28% body fat

    Energy Derived from Food

    • Energy is derived from food in the form of:
      • Carbohydrates (4 kcal/g, 16.8 kJ/g)
      • Fat (9.2 kcal/g, 38.6 kJ/g)
      • Protein (5.4 kcal/g, 22.7 kJ/g)
      • Alcohol (7 kcal/g, 29.4 kJ/g)

    Energy Balance and Control of Body Weight

    • Energy balance is the balance between energy intake and energy expenditure
    • Energy expenditure is influenced by:
      • Basal metabolic rate (BMR)
      • Diet-induced thermogenesis
      • Physical activity
      • Environmental temperature
      • Growth, pregnancy, and lactation
      • Age
    • Energy requirements depend on various factors, including BMR, diet, physical activity, and environmental temperature
    • Components of energy expenditure include:
      • BMR
      • Thermogenesis
      • Physical activity
      • Energy expenditure for growth, pregnancy, and lactation

    Regulation of Energy Intake

    • The hypothalamus plays a crucial role in regulating energy intake through:
      • Hunger centre
      • Satiety centre
      • Satiety signals (long-term and short-term)
    • Long-term satiety signals include:
      • Leptin and insulin
      • Neuropeptide Y (NPY) and ghrelin (hunger signals)
      • Pro-opiomelanocortin (POMC) related peptides (PYY3-36) and melanocortin peptides (inhibit hunger)
    • Short-term satiety signals come from:
      • The GI tract
      • The hepatic portal vein
      • The liver

    Causes of Obesity

    • Causes of obesity include:
      • Socio-economic and cultural factors
      • Endocrinological factors (rarely)
      • Physical activity
      • Microbiota (gut microbes)
      • Genetic factors (e.g., FTO gene)

    Consequences of Obesity

    • Obesity is associated with various conditions, including:
      • Cardiovascular disease
      • Diabetes mellitus type 2
      • Hypertension
      • Respiratory problems
      • Gall bladder stones
      • Osteoarthritis
      • Reduced fertility in men
      • Polycystic ovary syndrome
      • Breast, endometrial, colon, and prostate cancers

    Therapy: Diets

    • All diets work if energy intake is restricted, but most dieters regain weight
    • High protein diets can be easier to follow due to satiety value of protein
    • Keto diets are primarily used for reducing frequency of epileptic seizures in children, but may be used for weight loss
    • Intermittent fasting has been shown to have no benefit compared to continuous restriction of calories

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    Description

    This quiz covers the concept of body weight and energy balance, including body fat percentage in different age groups and genders. It's a part of the Nutrition and Metabolism module in MBBS stage 1.

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