Podcast
Questions and Answers
Which compartment in the body contains ⅔ of the total water weight?
Which compartment in the body contains ⅔ of the total water weight?
What is the primary determinant of intracellular/extracellular osmotic pressure?
What is the primary determinant of intracellular/extracellular osmotic pressure?
Which type of fluid overload is most commonly caused by medical treatment?
Which type of fluid overload is most commonly caused by medical treatment?
What is the ionic composition of Lactated Ringer's solution (LR) similar to?
What is the ionic composition of Lactated Ringer's solution (LR) similar to?
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What formula is used to calculate serum osmolality?
What formula is used to calculate serum osmolality?
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What type of fluid should be used for IV maintenance after major adult gastrointestinal surgery during the first 24 hours?
What type of fluid should be used for IV maintenance after major adult gastrointestinal surgery during the first 24 hours?
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Which medication is recommended for treating hyperphosphatemia associated with renal failure?
Which medication is recommended for treating hyperphosphatemia associated with renal failure?
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What is the most likely cause of hypophosphatemia associated with failure to wean from the ventilator and muscle weakness?
What is the most likely cause of hypophosphatemia associated with failure to wean from the ventilator and muscle weakness?
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What is the recommended treatment for respiratory acidosis due to high CO2 from low tidal volumes or low respiratory rate?
What is the recommended treatment for respiratory acidosis due to high CO2 from low tidal volumes or low respiratory rate?
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What is the primary cause of high anion gap acidosis known as 'MUDPILES'?
What is the primary cause of high anion gap acidosis known as 'MUDPILES'?
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What is the usual cause of normal anion gap acidosis?
What is the usual cause of normal anion gap acidosis?
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What can correction of acidosis lead to?
What can correction of acidosis lead to?
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What is the most important treatment for correcting the Cl− deficit in metabolic alkalosis?
What is the most important treatment for correcting the Cl− deficit in metabolic alkalosis?
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Which of the following is the best indicator of adequate volume replacement during open abdominal operations?
Which of the following is the best indicator of adequate volume replacement during open abdominal operations?
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What is the daily gastrointestinal fluid secretion range for the stomach?
What is the daily gastrointestinal fluid secretion range for the stomach?
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Which solution is recommended for replacement of fluid losses from sweat or gastric losses?
Which solution is recommended for replacement of fluid losses from sweat or gastric losses?
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What are the symptoms of hypernatremia?
What are the symptoms of hypernatremia?
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Which electrolyte can cause peaked T waves on EKG and arrhythmias when present in high levels?
Which electrolyte can cause peaked T waves on EKG and arrhythmias when present in high levels?
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What are the symptoms of hypokalemia?
What are the symptoms of hypokalemia?
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Which electrolyte imbalance may be caused by parathyroidectomy or magnesium deficiency?
Which electrolyte imbalance may be caused by parathyroidectomy or magnesium deficiency?
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What is the normal body potassium requirement per day in mEq/kg?
What is the normal body potassium requirement per day in mEq/kg?
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Which electrolyte imbalance can lead to perioral tingling and numbness, hyperreflexia, and prolonged QT interval?
Which electrolyte imbalance can lead to perioral tingling and numbness, hyperreflexia, and prolonged QT interval?
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What is the normal body sodium requirement per day in mEq/kg?
What is the normal body sodium requirement per day in mEq/kg?
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What is the most important treatment for correcting hyperkalemia?
What is the most important treatment for correcting hyperkalemia?
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What is the primary cause of high anion gap acidosis known as 'MUDPILES'?
What is the primary cause of high anion gap acidosis known as 'MUDPILES'?
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What type of fluid should be used for IV maintenance after major adult gastrointestinal surgery during the first 24 hours?
What type of fluid should be used for IV maintenance after major adult gastrointestinal surgery during the first 24 hours?
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Which compartment in the body contains ⅔ of the total water weight?
Which compartment in the body contains ⅔ of the total water weight?
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What are the symptoms of hypernatremia?
What are the symptoms of hypernatremia?
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Which electrolyte can cause peaked T waves on EKG and arrhythmias when present in high levels?
Which electrolyte can cause peaked T waves on EKG and arrhythmias when present in high levels?
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What is the ionic composition of normal saline (0.9%) solution?
What is the ionic composition of normal saline (0.9%) solution?
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Which fluid should be used for IV maintenance after major adult gastrointestinal surgery during the first 24 hours?
Which fluid should be used for IV maintenance after major adult gastrointestinal surgery during the first 24 hours?
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What is the recommended fluid to switch to after 24 hours of major adult gastrointestinal surgery?
What is the recommended fluid to switch to after 24 hours of major adult gastrointestinal surgery?
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What is the formula for calculating serum osmolality?
What is the formula for calculating serum osmolality?
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What is the most common cause of volume overload?
What is the most common cause of volume overload?
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Where does third space fluid reside in the body?
Where does third space fluid reside in the body?
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What determines the plasma/interstitial compartment oncotic pressures?
What determines the plasma/interstitial compartment oncotic pressures?
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Where does two-thirds of the extracellular water reside in the body?
Where does two-thirds of the extracellular water reside in the body?
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What is the primary cause of high anion gap acidosis known as 'MUDPILES'?
What is the primary cause of high anion gap acidosis known as 'MUDPILES'?
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What is the usual cause of normal anion gap acidosis?
What is the usual cause of normal anion gap acidosis?
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Which electrolyte imbalance may be caused by parathyroidectomy or magnesium deficiency?
Which electrolyte imbalance may be caused by parathyroidectomy or magnesium deficiency?
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What can correction of acidosis lead to?
What can correction of acidosis lead to?
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What is the most important treatment for correcting hyperkalemia?
What is the most important treatment for correcting hyperkalemia?
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Study Notes
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5% dextrose infusion stimulates insulin release and prevents protein breakdown, providing 150 g glucose per day (525 kcal/day).
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During open abdominal operations, normal fluid loss is 0.5–1.0 L/h, with insensible losses being 10 cc/kg/day (30 L/day for a 70 kg person).
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Best indicator of adequate volume replacement is urine output, with the goal being at least 0.5 cc/kg/h.
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Insensible losses increase with fever, burns, large open wounds, or ventilated patients.
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For significant dehydration, replace fluid losses with appropriate solutions based on the source: normal saline for sweat or gastric losses, and lactated Ringer's for pancreatic, biliary, or small bowel losses.
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Gastrointestinal fluid secretion ranges from 1–2 L/day for the stomach, 500–1,000 mL/day for the biliary and pancreatic systems, and 500–1,000 mL/day for the duodenum.
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Electrolyte losses include sodium, potassium, bicarbonate, and calcium, with various sources and methods for replacement depending on the electrolyte in question.
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Kidneys can remove electrolytes such as potassium, calcium, magnesium, phosphate, urea, and creatinine.
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Normal body potassium requirement is 0.5–1.0 mEq/kg/day, and normal sodium requirement is 1–2 mEq/kg/day.
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Hyperkalemia symptoms include peaked T waves on EKG and arrhythmias, and can be treated with calcium gluconate, insulin, and sodium bicarbonate.
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Hypokalemia symptoms include disappearing T waves, muscle cramps, fatigue, and weakness. It may also be due to pseudohyperkalemia.
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Hypernatremia symptoms include restlessness, irritability, seizures, and usually result from poor fluid intake.
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Hyponatremia symptoms include headaches, nausea, vomiting, seizures, and can be caused by fluid overload, isotonic fluid loss, or pseudohyponatremia.
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Hypocalcemia symptoms include perioral tingling and numbness, hyperreflexia, and prolonged QT interval, and may be caused by parathyroidectomy or magnesium deficiency.
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Hypomagnesemia symptoms include irritability, confusion, hyperreflexia, seizures, and may be caused by massive diuresis, chronic TPN without magnesium replacement, or ETOH abuse.
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Phosphate imbalances can result in various symptoms and may require specific treatment approaches.
-
Calcium levels can be affected by various factors and can cause significant symptoms.
-
Electrolyte balance is important to prevent complications and maintain overall health.
-
5% dextrose infusion stimulates insulin release and prevents protein breakdown, providing 150 g glucose per day (525 kcal/day).
-
During open abdominal operations, normal fluid loss is 0.5–1.0 L/h, with insensible losses being 10 cc/kg/day (30 L/day for a 70 kg person).
-
Best indicator of adequate volume replacement is urine output, with the goal being at least 0.5 cc/kg/h.
-
Insensible losses increase with fever, burns, large open wounds, or ventilated patients.
-
For significant dehydration, replace fluid losses with appropriate solutions based on the source: normal saline for sweat or gastric losses, and lactated Ringer's for pancreatic, biliary, or small bowel losses.
-
Gastrointestinal fluid secretion ranges from 1–2 L/day for the stomach, 500–1,000 mL/day for the biliary and pancreatic systems, and 500–1,000 mL/day for the duodenum.
-
Electrolyte losses include sodium, potassium, bicarbonate, and calcium, with various sources and methods for replacement depending on the electrolyte in question.
-
Kidneys can remove electrolytes such as potassium, calcium, magnesium, phosphate, urea, and creatinine.
-
Normal body potassium requirement is 0.5–1.0 mEq/kg/day, and normal sodium requirement is 1–2 mEq/kg/day.
-
Hyperkalemia symptoms include peaked T waves on EKG and arrhythmias, and can be treated with calcium gluconate, insulin, and sodium bicarbonate.
-
Hypokalemia symptoms include disappearing T waves, muscle cramps, fatigue, and weakness. It may also be due to pseudohyperkalemia.
-
Hypernatremia symptoms include restlessness, irritability, seizures, and usually result from poor fluid intake.
-
Hyponatremia symptoms include headaches, nausea, vomiting, seizures, and can be caused by fluid overload, isotonic fluid loss, or pseudohyponatremia.
-
Hypocalcemia symptoms include perioral tingling and numbness, hyperreflexia, and prolonged QT interval, and may be caused by parathyroidectomy or magnesium deficiency.
-
Hypomagnesemia symptoms include irritability, confusion, hyperreflexia, seizures, and may be caused by massive diuresis, chronic TPN without magnesium replacement, or ETOH abuse.
-
Phosphate imbalances can result in various symptoms and may require specific treatment approaches.
-
Calcium levels can be affected by various factors and can cause significant symptoms.
-
Electrolyte balance is important to prevent complications and maintain overall health.
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Description
Test your knowledge about the composition of total body water, including the distribution between intracellular and extracellular compartments, and the factors affecting it such as proteins and sodium. Explore the dynamics of body water and its implications for various physiological processes.