module 4 - acids-bases, electrolytes, fluids
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Questions and Answers

Which of the following is true about oncotic pressure?

  • It is constant along the length of the capillary (correct)
  • It decreases along the length of the capillary
  • It is higher when plasma protein concentration is low
  • It is lower when plasma protein concentration is high
  • What drives water and low molecular mass solutes out of the capillary?

  • Heart pumping
  • Osmotic pressure
  • Oncotic pressure
  • Hydrostatic pressure (correct)
  • What is the major cation in the extracellular fluid (ECF)?

  • Cl-
  • PO4-
  • Na+ (correct)
  • K+
  • Which of the following is true about the movement of water across cell membranes?

    <p>It is most affected by the concentration of serum sodium</p> Signup and view all the answers

    What happens to osmolality if serum glucose concentration is high?

    <p>It increases</p> Signup and view all the answers

    What is the formula to calculate plasma osmolality?

    <p>Osmolality = 2 x [Na+] + [glucose] + [urea nitrogen] in mmol/kg</p> Signup and view all the answers

    What is the major anion in the intracellular fluid (ICF)?

    <p>PO4-</p> Signup and view all the answers

    What is the role of sodium in the body?

    <p>Maintaining tonicity of extracellular fluid (ECF)</p> Signup and view all the answers

    What happens when there is too much sodium in the body?

    <p>The body filters more sodium into urine</p> Signup and view all the answers

    What happens to volume in the extracellular fluid (ECF) when there is water excess alone?

    <p>It increases</p> Signup and view all the answers

    Which of the following statements about pH is true?

    <p>If the [H+] is high, the pH is low (acidic)</p> Signup and view all the answers

    What is the pH range for arterial blood?

    <p>7.35 to 7.45</p> Signup and view all the answers

    Which of the following is a consequence of acidosis?

    <p>Excess acidity (low pH)</p> Signup and view all the answers

    What are the two broad classes of acid-base disorders?

    <p>Respiratory and metabolic</p> Signup and view all the answers

    What is the pKa value of His?

    <p>6.0</p> Signup and view all the answers

    Which body system excretes acid in the form of CO2?

    <p>Respiratory buffer system</p> Signup and view all the answers

    What is the pH range for most tissues?

    <p>7.0 to 7.4</p> Signup and view all the answers

    Which body system excretes H+ or regenerates/reabsorbs HCO3-?

    <p>Renal buffer system</p> Signup and view all the answers

    What is the net result of Imbalance (excess gain) in the bicarbonate-carbonic acid buffer system?

    <p>Leftwards increase</p> Signup and view all the answers

    Which body system shifts in response to excess acids and bases?

    <p>Blood buffer system</p> Signup and view all the answers

    Which of the following best defines osmosis?

    <p>The net flow of water across a semi-permeable barrier that equalizes solute concentrations</p> Signup and view all the answers

    Which of the following statements about osmotic potential is true?

    <p>Osmotic potential occurs when water moves from high osmolality to low osmolality</p> Signup and view all the answers

    Which of the following best describes tonicity?

    <p>The movement of water from low osmolality to high osmolality</p> Signup and view all the answers

    Which of the following is true about isotonic solutions?

    <p>There is no movement of water</p> Signup and view all the answers

    What is the formula for osmolality?

    <p>Osmolality = (Number of solute particles) / (Mass of water)</p> Signup and view all the answers

    Which of the following best describes hypertonic solutions?

    <p>Water moves out of the cell</p> Signup and view all the answers

    What is the main driving force for fluid shifts between the extracellular fluid (ECF) and intracellular fluid (ICF)?

    <p>Osmotic concentration of the ECF</p> Signup and view all the answers

    What is the difference between osmolality and osmolarity?

    <p>Osmolality cares about mass, while osmolarity cares about volume</p> Signup and view all the answers

    What happens to a cell in a hypotonic solution?

    <p>Water moves into the cell</p> Signup and view all the answers

    What drives fluid shifts between the extracellular fluid (ECF) and intracellular fluid (ICF)?

    <p>Disturbances to osmotic concentration of the ECF</p> Signup and view all the answers

    Study Notes

    Oncotic Pressure and Fluid Balance

    • Oncotic pressure drives water and low molecular mass solutes out of the capillary
    • The major cation in the extracellular fluid (ECF) is sodium
    • Water and low molecular mass solutes move out of the capillary due to hydrostatic pressure

    Osmolality and pH

    • Osmolality increases if serum glucose concentration is high
    • The formula to calculate plasma osmolality is not provided (but will be discussed later)
    • The major anion in the intracellular fluid (ICF) is not provided (but will be discussed later)

    Sodium and pH Regulation

    • Sodium plays a crucial role in the body, but excessive sodium leads to volume expansion in the extracellular fluid (ECF)
    • The body system that excretes acid in the form of CO2 is the respiratory system
    • The pH range for arterial blood is not provided (but will be discussed later)

    Acid-Base Balance

    • The two broad classes of acid-base disorders are respiratory and metabolic disorders
    • The pKa value of His is not provided (but will be discussed later)
    • Acidosis is a consequence of an imbalance in the bicarbonate-carbonic acid buffer system
    • The net result of an imbalance in the bicarbonate-carbonic acid buffer system is a change in pH

    Osmosis and Tonicity

    • Osmosis is the movement of water across cell membranes from high to low concentration
    • Osmotic potential is related to the concentration of solutes in a solution
    • Tonicity is the ability of a solution to change the volume of a cell
    • Isotonic solutions have the same concentration of solutes as the cell
    • Hypertonic solutions have a higher concentration of solutes than the cell
    • The formula for osmolality is not provided (but will be discussed later)
    • The main driving force for fluid shifts between the extracellular fluid (ECF) and intracellular fluid (ICF) is osmotic pressure
    • Osmolality and osmolarity differ in their units of measurement (osmolality is in osmoles per kilogram of solvent, osmolarity is in osmoles per liter of solution)
    • A cell in a hypotonic solution will swell and potentially lyse due to an influx of water

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    Midterm Review Quiz on Body Fluids, Electrolytes, and Acid-Base Balance

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