Body Fluids and Circulation Self-Assessment
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Questions and Answers

To maintain physiological function, the cells of the body require a constant supply of water (comprising ___ of the volume of fluid outside cells).

  • ~75%
  • ~25%
  • 100%
  • ~99% (correct)

Which one of the following does the extracellular fluid NOT comprise:

  • plasma
  • other body fluids
  • interstitial fluid
  • cytosol (correct)

The ionic concentrations and ____ of body fluids are as important as their absolute quantity:

  • density
  • volume
  • pH (correct)
  • mass

Stability of the volumes, solute concentrations and pH of the ECF and ICF involves each of the following inter-related processes, EXCEPT:

<p>density balance (D)</p> Signup and view all the answers

The body is in ___ when the amount of water gained each day is equal to the amount lost into the environment. The digestive system is the primary route for water gains while the urinary system is the primary route for water loss.

<p>fluid balance (B)</p> Signup and view all the answers

Fluid balance reflects primarily the control of ___ inside and outside of the cell and this is known as electrolyte balance.

<p>ionic concentrations (B)</p> Signup and view all the answers

___ are ions released through the breakdown of inorganic compounds and are so named because they conduct an electrical current in a solution.

<p>electrolytes (C)</p> Signup and view all the answers

Each day, body fluids gain electrolytes from ingested food and water, and lose electrolytes in urine, sweat and feces. If the gains and losses for each electrolyte are in balance, the body is said to be in:

<p>electrolyte balance (A)</p> Signup and view all the answers

Electrolyte balance primarily involves balancing the rates of absorption across the digestive tract with rates of loss at the:

<p>kidneys (A)</p> Signup and view all the answers

The body is in acid-base balance when the production of ___ in the body is precisely matched by their loss.

<p>hydrogen ions (C)</p> Signup and view all the answers

Preventing a reduction of pH is complicated as the body generates a variety of ___ during normal metabolism

<p>buffers (B)</p> Signup and view all the answers

The extracellular fluid (ECF) and the intracellular fluid (ICF) are called:

<p>fluid compartments (C)</p> Signup and view all the answers

The principal ions in the extracellular fluid (ECF) are all of the following, EXCEPT:

<p>potassium (K+) (B)</p> Signup and view all the answers

The principal components of the intracellular fluid (ICF) include large numbers of ___ proteins.

<p>polar (D)</p> Signup and view all the answers

Cell membranes are ___ and ions can only enter or leave by specific channels or carriers.

<p>selectively permeable (D)</p> Signup and view all the answers

Despite the differences in concentration of specific substances, the intracellular fluid (ICF) and extracellular fluid (ECF) ___ concentrations in most instances are identical as water can freely move across cell membranes.

<p>osmotic (C)</p> Signup and view all the answers

Minor components of the extracellular fluid (ECF) include each of the following, EXCEPT:

<p>lymph (A)</p> Signup and view all the answers

In clinical situations, it is customary to approximate that two-thirds of the total body water (TBW) is in the

<p>intracellular fluid (ICF) (A)</p> Signup and view all the answers

Continuous movement of water through the extracellular fluid (ECF) and intracellular fluid (ICF) functions to perform all of the following, EXCEPT:

<p>regulate body temperature (D)</p> Signup and view all the answers

Which of the following is NOT one of the four key concepts in the regulation of fluids and electrolytes?

<p>most fluids and electrolytes are normally lost by evaporation (D)</p> Signup and view all the answers

Which of the following hormones is NOT involved in the major physiological adjustments affecting fluid balance and electrolyte balance?

<p>insulin (A)</p> Signup and view all the answers

Which two major ions contribute to the osmotic concentrations of the extracellular fluid (ECF) and intracellular fluid (ICF), respectively?

<p>sodium and potassium (A)</p> Signup and view all the answers

___ are substances that combine with hydrogen (H+) ions (pH > 7).

<p>bases (D)</p> Signup and view all the answers

Slight changes in acid-base balance can cause each of the following, EXCEPT:

<p>edema (A)</p> Signup and view all the answers

Which of the following is NOT a major mechanism to maintain hydrogen (H+) ion homeostasis:

<p>chloride consumption (B)</p> Signup and view all the answers

Buffers are dissolved compounds that can remove:

<p>acids (B), hydroxide (OH-) ions (C)</p> Signup and view all the answers

Which of the following is NOT one of the three main acid-base buffer systems:

<p>carbohydrate (A)</p> Signup and view all the answers

The functions of blood include each of the following, EXCEPT:

<p>supporting and cushioning the central nervous system (CNS) (C)</p> Signup and view all the answers

Formed elements of blood include each of the following, EXCEPT:

<p>plasma (B)</p> Signup and view all the answers

Red blood cells are formed by differentiation of embryonic stem cells ______ in the red bone marrow.

<p>erythropoiesis</p> Signup and view all the answers

Which of the following white blood cell types is responsible for the body's specific defenses?

<p>lymphocytes (C)</p> Signup and view all the answers

Which of the following is NOT a function of platelets?

<p>scar formation (A)</p> Signup and view all the answers

The cessation of bleeding is also called:

<p>haemostasis (D)</p> Signup and view all the answers

The three phases of haemostasis include each of the following, EXCEPT:

<p>scar phase (D)</p> Signup and view all the answers

The ___ pathway - which begins when enzymes from either the extrinsic or intrinsic pathways activate Factor X starting a cascade ending with conversion of fibrinogen to fibrin.

<p>common</p> Signup and view all the answers

Which of the following is NOT an organ of the lymphatic system?

<p>kidney (D)</p> Signup and view all the answers

Lymphatic vessels carry lymph from peripheral tissues through the lymph nodes (which filtrate foreign substances from lymph) to the:

<p>venous system (B)</p> Signup and view all the answers

Movement of interstitial fluid into lymphatic vessels depends on the interstitial fluid ___ pressure.

<p>hydrostatic (B)</p> Signup and view all the answers

The blockage of lymphatic vessels can result in a rise in the volume of interstitial fluid, which can result in a massive regional:

<p>edema (C)</p> Signup and view all the answers

Which one of the following is part of the lymphatic system's non-specific defenses?

<p>inflammation (D)</p> Signup and view all the answers

Flashcards

Extracellular Fluid (ECF)

The fluid found outside of cells. It comprises about 1/3 of the total body water.

Intracellular Fluid (ICF)

The fluid found inside cells.

Fluid Balance

The process of maintaining a stable volume of water in the body.

Electrolyte Balance

Maintaining the proper concentration of electrolytes in the body fluids.

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Acid-Base Balance

Maintaining the proper pH of the body fluids.

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Digestive System

The primary route for water gain in the body.

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Urinary System

The primary route for water loss in the body.

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Electrolytes

Ions released through the breakdown of inorganic compounds that conduct electrical currents in solution.

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Electrolyte Balance

The body is considered to be in this state when the gain and loss of electrolytes are in balance.

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Kidneys

The primary site of electrolyte loss in the body.

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Acid-Base Balance

The production and loss of hydrogen ions in the body must be balanced to maintain proper pH.

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Bases

Substances that can remove hydrogen (H+) ions in a solution.

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Fluid Compartments

The ECF and ICF are referred to as this because they are separate compartments.

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Sodium (Na+), Potassium (K+), Chloride (Cl-), Bicarbonate (HCO3-)

The major ions found in the extracellular fluid.

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Negatively Charged Proteins

The major proteins found in the intracellular fluid.

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Selectively Permeable

Cell membranes allow some substances to pass through while blocking others.

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Osmotic Concentrations

The osmotic concentrations of the ICF and ECF are usually identical because water can move freely across cell membranes.

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Lymph, Aqueous Humor, Cerebrospinal Fluid (CSF), Plasma

Examples of minor components of the ECF.

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Intracellular Fluid (ICF)

The majority of total body water is located in this fluid compartment.

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Water Movement

The continuous movement of water between the ECF and ICF ensures communication and transport of substances.

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Water Transport

Cells cannot actively transport water molecules across their membranes.

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Antidiuretic Hormone (ADH), Insulin, Aldosterone, Natriuretic Peptides (ANP and BNP)

The major hormones involved in fluid and electrolyte balance.

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Sodium (Na+) and Potassium (K+)

The two major ions that determine the osmotic concentrations of the ECF and ICF.

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Bases

Substances that combine with hydrogen (H+) ions in a solution.

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Acid Generation

The body generates a variety of acids during normal metabolism, making it difficult to prevent a drop in pH.

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Bicarbonate, Phosphate, Protein

The three main acid-base buffer systems.

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Haemostasis

The cessation of bleeding, a vital process for maintaining blood volume and preventing blood loss.

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Vascular Phase, Platelet Phase, Coagulation Phase

The three phases of haemostasis.

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Common Pathway

The final stage of the coagulation cascade where fibrinogen is converted to fibrin, forming a stable clot.

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Kidney

The organ that is NOT part of the lymphatic system.

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Hydrostatic Pressure

Movement of interstitial fluid into lymphatic vessels is driven by this pressure.

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Edema

The blocking of lymphatic vessels can lead to this condition, resulting in accumulation of excess fluid in the interstitial space.

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Inflammation

Inflammation is a part of the body's non-specific defenses.

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Study Notes

Body Fluids and Circulation Self-Assessment

  • Water Requirements: Cells require a constant water supply, comprising approximately 75% of the fluid outside cells.

  • Extracellular Fluid Composition: Extracellular fluid does not include cytosol.

  • Ionic Concentrations: The concentrations and quantity of body fluid ions (e.g., volume, pH, density) are critical to bodily functions.

  • Fluid Balance Regulation: Stability of fluid volumes, solute concentrations, and pH is maintained through interconnected processes like fluid balance, electrolyte balance, and acid-base balance.

  • Water Balance: When water intake equals water output, it is considered a state of water balance

  • Fluid Balance Control: Fluid balance is primarily controlled by electrolyte balance processes. For example, the cell's control of ionic concentrations.

  • Electrolytes: Electrolytes are ions released through inorganic compounds, able to conduct electrical currents in solution.

  • Body Electrolyte Regulation: Daily gains and losses of electrolytes in fluids (ingested food and water vs. urine, sweat, feces) need to be balanced for the body to maintain homeostasis.

  • Acid-Base Balance: Acid-base balance occurs when the production of hydrogen ions is precisely matched by their loss.

  • Fluid Compartments: The body fluids are divided into extracellular fluid (ECF) and intracellular fluid (ICF).

  • Major Extracellular Ions: The ECF primarily consists of Sodium, potassium, chloride, and bicarbonate.

  • Intracellular Components : The ICF has numerous protein molecules.

  • Membrane Permeability: Cell membranes are selectively permeable, regulating the passage of ions and other substances.

  • Body Fluid Movement to Maintain Homeostasis: The continuous movement of water through the ECF and ICF helps maintain communication between fluids and regulates body temperature, accelerating the transport of nutrients, hormones, and dissolved gases.

  • Hormonal Regulation: Several hormones, like antidiuretic hormone (ADH), aldosterone, and the natriuretic peptides (ANP and BNP) play roles in regulating fluid and electrolyte balance.

  • Buffer Systems: The body uses buffer systems (e.g., bicarbonate, phosphate, protein) to maintain appropriate pH conditions.

  • Blood Functions: Blood transport dissolved gases, nutrients, hormones, and waste; supports and cushions the CNS; regulates temperature; and supports immunity.

  • Blood Components: Blood consists of formed elements (red blood cells, white blood cells, platelets) and plasma.

  • Lymphatic System Components: The organs of the lymphatic system are the lymph nodes, thymus, and spleen, among others.

  • Lymphatic Vessels: Lymphatic vessels transport lymph fluid with foreign substances filtered through lymph nodes before returning it to the circulatory system.

  • Interstitial Fluid Pressure and Movement: Movement of interstitial fluid into lymphatic vessels relies on hydrostatic pressure.

  • Body Blockage and Edema: Loss of lymphatic vessels can lead to the buildup of interstitial fluid and a condition known as edema.

  • Immune System Function: Lymphatic system components like lymphocytes play a role in the body's specific immune defenses. The lymphatic system also plays a role in non-specific defenses like inflammation.

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Description

Test your knowledge on body fluids and circulation with this self-assessment quiz. Explore key concepts such as water requirements, extracellular fluid composition, and the regulation of fluid balance. Understand the critical role of electrolytes and ionic concentrations in maintaining bodily functions.

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