Body Defence and Immunity Quiz
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Questions and Answers

Which of the following best defines immunity?

  • A temporary state of being free from illness.
  • The state of protection against infectious disease. (correct)
  • The process of getting sick from a disease.
  • The body's allergic reaction to foreign agents.
  • Innate immunity relies on previous exposure to a specific microorganism.

    False (B)

    Name two ways that passive immunity can be acquired naturally.

    Via the placenta or breast milk

    Adaptive immunity is characterized by immunological ________.

    <p>memory</p> Signup and view all the answers

    Match the type of immunity with the relevant description:

    <p>Innate Immunity = Present from birth, non-specific Adaptive Immunity = Develops after exposure, specific response Active Immunity = Body produces its own antibodies Passive Immunity = Receiving antibodies from another source</p> Signup and view all the answers

    Which of the following cells are NOT part of the innate immune response?

    <p>T lymphocytes (B)</p> Signup and view all the answers

    Immunization with a vaccine leads to passive immunity.

    <p>False (B)</p> Signup and view all the answers

    What type of immunity is gained through direct injection of antibodies?

    <p>Passive immunity</p> Signup and view all the answers

    Which of the following is an example of a live attenuated vaccine?

    <p>Oral polio vaccine (C)</p> Signup and view all the answers

    Antitoxins provide long-lasting immunity.

    <p>False (B)</p> Signup and view all the answers

    What is the main purpose of vaccines?

    <p>To stimulate the production of protective antibodies and other immune mechanisms against a specific disease.</p> Signup and view all the answers

    The BCG vaccine is given against ______.

    <p>Tuberculosis</p> Signup and view all the answers

    Match the following immunizing agents with their types:

    <p>Live attenuated vaccine = BCG vaccine Killed vaccine = Typhoid vaccine Toxoid = Tetanus toxoid Non-human immunoglobulin = Diphtheria antisera</p> Signup and view all the answers

    Which type of immunity is acquired through vaccination?

    <p>Artificially acquired active immunity (D)</p> Signup and view all the answers

    Gamma globulin provides long-term active immunity.

    <p>False (B)</p> Signup and view all the answers

    Immunoglobulins are also known as ______.

    <p>antibodies</p> Signup and view all the answers

    Which type of immunity is NOT present at birth?

    <p>Adaptive immunity (B)</p> Signup and view all the answers

    Artificially acquired active immunity results from the direct transfer of antibodies from another person or animal.

    <p>False (B)</p> Signup and view all the answers

    What is the primary way naturally acquired passive immunity is passed from mother to baby?

    <p>Through the placenta and breast milk</p> Signup and view all the answers

    A vaccine, like the BCG vaccine for Tuberculosis, provides ______ acquired active immunity.

    <p>artificially</p> Signup and view all the answers

    Exposure to which of these diseases can lead to naturally acquired active immunity?

    <p>Measles (D)</p> Signup and view all the answers

    Artificially acquired passive immunity results in the production of memory cells.

    <p>False (B)</p> Signup and view all the answers

    What is the key difference between naturally acquired active immunity and artificially acquired active immunity?

    <p>Naturally acquired results from natural exposure to an antigen whereas artificially acquired is delivered through vaccination.</p> Signup and view all the answers

    Match the type of immunity with its description:

    <p>Naturally Passive Acquired Immunity = Antibodies are passed from mother to baby. Naturally Active Acquired Immunity = Immunity develops after exposure to an antigen. Artificially Acquired Active Immunity = Immunity develops after vaccination. Artificially Acquired Passive Immunity = Immunity results from injection of antibodies.</p> Signup and view all the answers

    Which of the following is an example of a vaccine containing a killed or inactivated microbe?

    <p>Rabies vaccine (D)</p> Signup and view all the answers

    A toxoid vaccine contains a live, weakened form of a pathogen.

    <p>False (B)</p> Signup and view all the answers

    What type of immunity is provided by an antiserum?

    <p>Passive immunity</p> Signup and view all the answers

    The hepatitis B vaccine is an example of a vaccine produced using ______ technology.

    <p>recombinant DNA</p> Signup and view all the answers

    Which of these vaccines contain fragments of microorganisms?

    <p>Haemophilus influenzae type b vaccine (B)</p> Signup and view all the answers

    Match the following vaccine types with their appropriate examples:

    <p>Live (attenuated) virus = Measles vaccine Toxoid = Diphtheria vaccine Killed or inactivated microbe = Influenza vaccine Recombinant DNA = Hepatitis B vaccine</p> Signup and view all the answers

    Immune globulin (IG) provides active artificially acquired immunity.

    <p>False (B)</p> Signup and view all the answers

    What is the primary source of antibodies in an antiserum?

    <p>Animal blood (D)</p> Signup and view all the answers

    Flashcards

    Immunity

    The ability of an organism to resist infection and disease, either through an immune response triggered by immunization or previous infection, or via other non-immunological factors.

    Innate Immunity

    Refers to the body's innate, non-specific defense mechanisms present from birth. It's the first line of defense against foreign pathogens.

    Cells involved in innate immunity

    Consists of specialized cells like dendritic cells (DCs), natural killer (NK) cells, macrophages, neutrophils, basophils, eosinophils, and mast cells.

    Adaptive Immunity

    Protection developed after exposure to a specific antigen. It involves B and T lymphocytes, leading to immunological memory.

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    Acquired immunity

    Acquired immunity resulting from the active production or receipt of antibodies.

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    Naturally acquired active immunity

    Protection gained by getting the disease naturally.

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    Artificially acquired active immunity

    Protection gained through immunization with a vaccine that stimulates the body to produce its own antibodies.

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    Artificially acquired passive immunity

    Protection acquired by direct injection of antibodies (immunoglobulin).

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    Naturally Acquired Passive Immunity

    Immunity acquired by receiving antibodies from another person or animal, like a mother passing antibodies to her baby.

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    Natural Immunity

    The type of immunity that is naturally acquired through exposure to an antigen.

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    Artificial Immunity

    The type of immunity that is acquired through artificial means, such as vaccination.

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    Antiserum

    A substance containing antibodies or immune cells that is introduced into the body to provide passive immunity.

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    Antitoxin

    A type of antiserum that contains antibodies specifically against toxins produced by bacteria.

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    Gamma globulin

    A concentrated solution of antibodies extracted from the blood of human donors. It provides passive immunity against various diseases.

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    Active immunity

    Immunity acquired through direct exposure to an infectious agent, either naturally through illness or artificially through vaccination.

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    Passive immunity

    Immunity acquired by receiving pre-made antibodies, rather than your body producing them itself. This immunity is temporary.

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    Immunizing agents

    Substances used to stimulate the immune system to produce immunity against specific diseases.

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    Live attenuated vaccines

    Vaccines that use weakened forms of the infectious agent. While they can cause a mild form of the disease, they are effective in stimulating a strong immune response.

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    Inactivated vaccines

    Vaccines that contain inactive or killed versions of the infectious agent, stimulating the immune system without causing the disease.

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    Killed or Inactivated Microbial Vaccines

    Vaccines containing killed or inactivated microbes, such as the rabies vaccine with whole, killed rabies viruses and the influenza vaccine with inactivated influenza viruses.

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    Fragment Vaccines

    Vaccines containing fragments of microorganisms, like the Hemophilus influenzae type b vaccine.

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    Recombinant DNA Technology for Vaccines

    DNA from two or more sources combined in a single molecule, commonly used for vaccine creation. Examples include the Hepatitis B vaccine (HepB), Diphtheria, Tetanus, Acellular Pertussis (DTaP) vaccine, and Hepatitis A vaccine (HepA).

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    Toxoid Vaccines

    An exotoxin treated to be nonpoisonous but still capable of stimulating an immune response against the natural exotoxin. Examples include the tetanus and diphtheria vaccines.

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    Immune Globulin (IG)

    Antibody-containing serum obtained from another person. An example is Human Hepatitis B Immunoglobulin (HBIG) used to prevent hepatitis B in those not actively immunized.

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    Passive Artificially Acquired Immunity

    A type of vaccine that provides immediate but temporary protection. Examples include the measles, mumps, rubella (MMR) vaccine, the oral polio vaccine, and the yellow fever vaccine.

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    Study Notes

    Body Defence and Immunity

    • Immunity is the state of protection against infectious diseases. It's gained through immune responses from immunization or past infection, or other non-immunological factors.

    Learning Outcomes

    • Students should be able to define immunity.
    • Students should be able to describe different types of immunity.
    • Students should be able to identify methods for acquiring different types of immunity.
    • Students should be able to identify different types of vaccines.

    Types of Immunity

    • Innate Immunity: This is the non-specific first line of defense against foreign pathogens. It's an integral part of the overall immune response. It's mediated by cells like dendritic cells (DCs), natural killer (NK) cells, macrophages, neutrophils, basophils, eosinophils, and mast cells. Innate immunity is present from birth and is effective against potential infections. It does not rely on prior experience with microorganisms.

    • Adaptive Immunity: This type of immunity develops throughout life. It targets specific pathogens following exposure to specific antigens. It's mediated by B and T lymphocytes, and it features immunological memory. It isn't present from birth.

      • Naturally Acquired: Acquired immunity can be acquired in two ways:

        • Passive: Antibodies are received from another person or animal. This protection is usually temporary. Examples include IgG transfer from mother to fetus across the placenta, and IgA transfer from mother to baby in breast milk.
        • Active: Antibodies are produced by the immune system in response to the presence of antigens. This protection is generally long-lasting. Naturally acquired active immunity occurs after exposure to a pathogenic microorganism. Examples include infections with diseases like measles, mumps, and chicken pox.
      • Artificially Acquired: Acquired immunity can be artificially achieved:

        • Passive: Antibodies are directly injected from another person or animal. This protection is short-lived and provides immediate protection. Examples include using antiserum, antitoxin, and gamma globulin. This is used when the body does not have time to mount a response.
        • Active: Antigens are introduced into the body via vaccines to artificially stimulate an immune response. This leads to the production of memory cells. Examples of vaccines include:
          • Live attenuated vaccines: measles, mumps, rubella (MMR), BCG (Bacille Calmette-Guerin), oral polio,
          • Inactivated or killed vaccines: typhoid, cholera, rabies, polio (Salk),
          • Toxoids: diphtheria, tetanus

    Immunizing Agents

    • Vaccines: Immunological preparations used to induce immunity against specific diseases. They are prepared from live attenuated, inactivated, or killed microorganisms, or from antigens produced through recombinant DNA technology; or from toxoids. Examples:
      • BCG, which is used against tuberculosis
      • Toxoids to combat diphtheria and tetanus
      • Polio vaccines, both inactivated and live attenuated forms
      • Vaccines against hepatitis, including hepatitis A and B
      • MMR vaccine for measles, mumps, and rubella
    • Immunoglobulin (Ig): Antibody-containing serum from another person or animal.
      • Examples include:

      • Human immunoglobulin: normal Ig (used for general protection), specific Ig (used to target particular pathogens, e.g., hepatitis B immunoglobulin)

      • Non-human immunoglobulin (antisera): used to fight diphtheria, tetanus, gas gangrene, botulism, and rabies.

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    Description

    Test your understanding of body defence and immunity concepts. This quiz covers definitions, types of immunity, and methods of acquiring immunity. Ideal for students learning about the immune system and vaccinations.

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