BM402: Engineering in Medicine Pop Quiz
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Questions and Answers

What does EEG stand for?

Electroencephalogram

EEG is a picture/record of electrical signals in the brain.

True (A)

Which of the following is NOT a brain rhythm or frequency band?

  • Delta
  • Gamma
  • Beta
  • Theta
  • Lambda (correct)
  • Alpha

What are the main EEG artifacts in simultaneous EEG-fMRI?

<p>Cardioballistic artifacts (B), Gradient artifacts (C)</p> Signup and view all the answers

What is the frequency range of gamma brain waves?

<blockquote> <p>35 Hz</p> </blockquote> Signup and view all the answers

What is the frequency range of EEG ripples?

<p>80–200 Hz</p> Signup and view all the answers

Events related potentials (ERPs) are evoked by stimuli and measured at the scalp with EEG.

<p>True (A)</p> Signup and view all the answers

What is the name of the positive going ERP component at 300 ms?

<p>P300</p> Signup and view all the answers

The amplitude of the P300 decreases as the demand for cognitive resources increases.

<p>False (B)</p> Signup and view all the answers

What is the name of the disorder where the P300 latency is prolonged and the amplitude is reduced?

<p>Schizophrenia</p> Signup and view all the answers

The P300 amplitude is reduced in both chronic bipolar patients and schizophrenia patients.

<p>True (A)</p> Signup and view all the answers

A single dose of caffeine can lead to a smaller P300 amplitude and a shorter latency.

<p>True (A)</p> Signup and view all the answers

Emotions can have a significant impact on our physiological responses, including our heart rate and respiratory rate.

<p>True (A)</p> Signup and view all the answers

Which of the following brain structures is NOT involved in dealing with stress and fear?

<p>Hippocampus (A)</p> Signup and view all the answers

Recalling happy events activates various areas of the brain including the anterior cingulate cortex, prefrontal cortex, and insula.

<p>True (A)</p> Signup and view all the answers

Real-time fMRI (rtfMRI) allows investigation of human brain neuroplastic changes.

<p>True (A)</p> Signup and view all the answers

What is the name of the brain region that plays major roles in emotional processing?

<p>Amygdala</p> Signup and view all the answers

Subjects in neurofeedback training can self-regulate their amygdala activity.

<p>True (A)</p> Signup and view all the answers

Neurofeedback is a type of biofeedback that teaches self-regulation of brain activity.

<p>True (A)</p> Signup and view all the answers

A Brain-Computer Interface (BCI) allows users to control devices using thought.

<p>True (A)</p> Signup and view all the answers

What is the main technological difference between neurofeedback and a Brain-Computer Interface (BCI)?

<p>Neurofeedback focuses on self-regulation, while BCIs translate brain signals into commands. (B)</p> Signup and view all the answers

What is the term for the operant conditioning technique designed to learn how to control one's brain activity to improve cognitive performance, regulate stress levels, emotional functioning, and behavior?

<p>Neurofeedback</p> Signup and view all the answers

Neurofeedback can be used to improve working memory in individuals with schizophrenia.

<p>True (A)</p> Signup and view all the answers

Higher treatment doses of neurofeedback generally result in greater cognitive gains.

<p>True (A)</p> Signup and view all the answers

Participants in neurofeedback training often experience boredom and burnout with longer protocols.

<p>True (A)</p> Signup and view all the answers

Delivering the same treatment dose of neurofeedback over a shorter period, such as 12 hours over 6 weeks, could potentially improve efficacy.

<p>True (A)</p> Signup and view all the answers

Flashcards

EEG

Electroencephalogram; a measurement of electrical patterns on the scalp reflecting cortical activity (brainwaves).

fMRI

Functional Magnetic Resonance Imaging; a neuroimaging technique measuring brain activity by detecting changes associated with blood flow.

Simultaneous EEG-fMRI

Recording both EEG and fMRI data at the same time, allowing for study of brain activity and electrical patterns.

EEG Artifacts (Simultaneous EEG-fMRI)

Unwanted signals in EEG data (noise) during simultaneous EEG-fMRI recordings caused by magnetic fields and RF emissions.

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Event-related potential (ERP)

Neural response associated with a sensory, cognitive, or motor event recorded with scalp EEG, averaged over multiple trials.

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P300 (ERP)

Positive-going ERP component at 300ms; relates to memory processing and cognitive resources.

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ERP in Psychiatric Disorders

ERP changes observed in conditions like schizophrenia and bipolar disorder, often showing altered latency and amplitude (e.g., P300).

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Neurofeedback

Using real-time feedback from brain imaging (e.g., fMRI) to regulate brain activity.

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Real-time fMRI (rtfMRI)

fMRI data processed and displayed concurrently with data acquisition; enabling real-time neurofeedback.

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EEG Frequency Bands

Different ranges of brainwave frequencies (e.g., delta, theta, alpha, beta) associated with different brain states and activities.

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Alpha Rhythm

Brainwave pattern associated with periods of relaxation and inactivity, often generated by the thalamus.

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Cortical Inactivity

Period when the cerebral cortex is less active.

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EEG Ripples

Fast oscillations in the EEG (80-200 Hz) linked to various brain activities.

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Emotions and Physiology

Emotions have a significant impact on physiological responses like heart rate and breathing.

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Stress Hormones

Hormones like adrenaline released during stress and fear.

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Brain Structures for Stress

Certain brain areas involved in processing stress and fear (not specified by the provided text).

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Happiness and Brain Activation

Recalling happy events activates brain areas like the anterior cingulate cortex, prefrontal cortex, and insula.

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Gradient Artifacts

Distortions in EEG data caused by gradient fields in fMRI.

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Study Notes

BM402: Engineering in Medicine - Pop Quiz

  • Date: October 31, 2024
  • Time: 1:10 PM - 1:40 PM
  • Location: M 2170 - South Campus
  • Format: Pop quiz
  • Duration: Approximately 30 minutes
  • Break: 15 minutes

Topics for Pop Quiz

  • MRI
  • Functional MRI
  • Applications of MRI and fMRI
  • EEG
  • Challenges of EEG-fMRI
  • Literature
  • EEG basics
  • Electrical
  • EEG cap
  • Amplifier
  • Processing

EEG Basics

  • Electro-encephalo-gram (EEG): Measurement of electrical patterns on the scalp reflecting cortical activity.
  • Brainwaves: Electrical activity patterns in the brain.
  • Frequency Bands: EEG signals are categorized based on their frequency, impacting mental states.

EEG - Brain Rhythms & Frequency Bands

  • Gamma (γ): >35 Hz, associated with problem-solving and concentration.
  • Beta (β): 12-35 Hz, associated with busy, active mind, anxiety, external attention.
  • Alpha (α): 8-12 Hz, associated with reflective, restful states, relaxed, passive attention
  • Theta (θ): 4-8 Hz, associated with drowsiness, deeply relaxed, inward focused.
  • Delta (δ): 0.5-4 Hz, associated with sleep, dreaming

Simultaneous EEG-fMRI:

  • Compatibility Requirements: Maintaining image quality, mitigating artifacts (magnetic field effects, radiofrequency emissions), and preventing ferrous materials.

Simultaneous EEG-fMRI: Main Artifacts

  • Gradient and Cardioballistic Artifacts: These artifacts are corrected to improve data quality.
  • Definition: Neural responses associated with sensory, cognitive, or motor events.
  • Recording: Averaging voltage changes after stimulus onset across multiple trials.
  • Components: (e.g., P300), represent cognitive processing.
  • Significance of P300: Amplitude correlates with cognitive resources demanded and stimulus relevance.
  • Schizophrenia and Chronic Bipolar Patients: Both show latency prolongation and amplitude reduction in auditory P300 responses.

Caffeine effect on P300

  • Acute effect: A single dose of caffeine slightly decreases P300 amplitude and latency.

High-Frequency EEG

  • EEG Ripples: 80-200 Hz oscillations related to brain processes.
  • High-Frequency EEG Activity Application: Not explicitly stated in the provided documents.

Physiology, Emotions, and Brain

  • Emotional impact: Emotions affect physiological responses (e.g., heart rate, breathing).
  • Fear, Anger, and Anxiety: Release adrenaline, leading to increased heart rate and rapid breathing.
  • Happiness: Associated with endorphin release, slower heart rate, and shallower breathing.

Happiness and fMRI

  • Happy Memories Condition: Participants recall and experience happy memories to visualize and elevate brain activity.

Activation Network

  • Brain Activity: Happy memories activate brain regions including the anterior cingulate cortex, prefrontal cortex, and insula.

Neurofeedback (NFB)

  • Mechanism: Operant conditioning of brain activity, to enhance cognitive functions or manage conditions.
  • Tools: Using EEG and signal processing, the system provides real-time feedback to monitor and enhance mental state.

Brain-Computer Interface (BCI)

  • Mechanism: Enables direct communication between the brain and external devices using thought.
  • Relationship to Neurofeedback: Neurofeedback can be viewed as a specific application of BCI, but has a primary focus on self-regulation.

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Prepare for the BM402 pop quiz covering critical topics in Engineering in Medicine, including MRI, fMRI, and EEG basics. This quiz will test your understanding of brain activities and their measurement techniques. Get ready to demonstrate your knowledge!

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