Blood Pressure Regulation and ACE Inhibitors Quiz

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What is the primary physiological regulation of blood pressure in relation to vascular resistance?

Decreased total peripheral resistance (correct)

Activation of the RAAS system

Increased cardiac output

Sympathetic nervous system stimulation

Which medication class is specifically known for inhibiting the RAAS system and reducing the effects of angiotensin II?

Beta blockers

Diuretics

Calcium channel blockers

Angiotensin-converting enzyme inhibitors (ACEIs) (correct)

What is a common adverse drug reaction (ADR) associated with ACEIs?

Hypernatremia

Hypocalcemia

Hypokalemia

Hyperkalemia (correct)

Which medication is generally preferred for hypertension management during pregnancy?

Calcium channel blockers Signup and view all the answers

Which condition would be a contraindication for the use of aliskiren?

Chronic kidney disease Signup and view all the answers

What is a potential effect of ACE inhibitors (ACEIs) on potassium levels?

Decrease in potassium levels Signup and view all the answers

In terms of lipid profile, what effect do ARBs have on total cholesterol and LDL?

No effect on total cholesterol and LDL Signup and view all the answers

Which of the following is NOT a characteristic commonly associated with captopril?

Long-acting formulation Signup and view all the answers

What is the primary pharmacological mechanism of action (MOA) of aliskiren?

Direct renin inhibitor Signup and view all the answers

When considering the use of ACEIs or ARBs, which condition would generally be advised to avoid due to potential complications?

Chronic kidney disease Signup and view all the answers

What is a potential effect of aliskiren on potassium levels?

Hyperkalemia Signup and view all the answers

Which characteristic is NOT commonly associated with ACEIs in terms of their effects on lipid profile?

Increase in HDL levels Signup and view all the answers

What is a common contraindication for the use of ACEIs and ARBs?

Pregnancy Signup and view all the answers

Which medication class is known to have a primary effect on reducing peripheral vascular resistance (PVR)?

Calcium channel blockers Signup and view all the answers

Which drug is considered the top choice for managing hypertension specifically induced by other medications?

ACEIs Signup and view all the answers

What is the primary mechanism of action of angiotensin II effects in blood pressure regulation?

Stimulating aldosterone release Signup and view all the answers

Which characteristic differentiates ACEIs from ARBs in terms of their effects on lipid profile?

ACEIs increase HDL levels Signup and view all the answers

How does aliskiren primarily exert its pharmacological effect?

Directly inhibiting renin activity Signup and view all the answers

Which condition is generally advised to avoid when using ACEIs or ARBs to manage hypertension?

Hyperkalemia Signup and view all the answers

What is the drug of choice for hypertension management during pregnancy?

Captopril Signup and view all the answers