Blood Pressure Regulation and ACE Inhibitors Quiz
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Questions and Answers

What is the primary physiological regulation of blood pressure in relation to vascular resistance?

  • Decreased total peripheral resistance (correct)
  • Activation of the RAAS system
  • Increased cardiac output
  • Sympathetic nervous system stimulation
  • Which medication class is specifically known for inhibiting the RAAS system and reducing the effects of angiotensin II?

  • Beta blockers
  • Diuretics
  • Calcium channel blockers
  • Angiotensin-converting enzyme inhibitors (ACEIs) (correct)
  • What is a common adverse drug reaction (ADR) associated with ACEIs?

  • Hypernatremia
  • Hypocalcemia
  • Hypokalemia
  • Hyperkalemia (correct)
  • Which medication is generally preferred for hypertension management during pregnancy?

    <p>Calcium channel blockers</p> Signup and view all the answers

    Which condition would be a contraindication for the use of aliskiren?

    <p>Chronic kidney disease</p> Signup and view all the answers

    What is a potential effect of ACE inhibitors (ACEIs) on potassium levels?

    <p>Decrease in potassium levels</p> Signup and view all the answers

    In terms of lipid profile, what effect do ARBs have on total cholesterol and LDL?

    <p>No effect on total cholesterol and LDL</p> Signup and view all the answers

    Which of the following is NOT a characteristic commonly associated with captopril?

    <p>Long-acting formulation</p> Signup and view all the answers

    What is the primary pharmacological mechanism of action (MOA) of aliskiren?

    <p>Direct renin inhibitor</p> Signup and view all the answers

    When considering the use of ACEIs or ARBs, which condition would generally be advised to avoid due to potential complications?

    <p>Chronic kidney disease</p> Signup and view all the answers

    What is a potential effect of aliskiren on potassium levels?

    <p>Hyperkalemia</p> Signup and view all the answers

    Which characteristic is NOT commonly associated with ACEIs in terms of their effects on lipid profile?

    <p>Increase in HDL levels</p> Signup and view all the answers

    What is a common contraindication for the use of ACEIs and ARBs?

    <p>Pregnancy</p> Signup and view all the answers

    Which medication class is known to have a primary effect on reducing peripheral vascular resistance (PVR)?

    <p>Calcium channel blockers</p> Signup and view all the answers

    Which drug is considered the top choice for managing hypertension specifically induced by other medications?

    <p>ACEIs</p> Signup and view all the answers

    What is the primary mechanism of action of angiotensin II effects in blood pressure regulation?

    <p>Stimulating aldosterone release</p> Signup and view all the answers

    Which characteristic differentiates ACEIs from ARBs in terms of their effects on lipid profile?

    <p>ACEIs increase HDL levels</p> Signup and view all the answers

    How does aliskiren primarily exert its pharmacological effect?

    <p>Directly inhibiting renin activity</p> Signup and view all the answers

    Which condition is generally advised to avoid when using ACEIs or ARBs to manage hypertension?

    <p>Hyperkalemia</p> Signup and view all the answers

    What is the drug of choice for hypertension management during pregnancy?

    <p>Captopril</p> Signup and view all the answers

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