Cardio Lec 06

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Questions and Answers

What affects the mean arterial pressure (MAP)?

  • Heart rate and blood volume
  • Cardiac output and arteriolar resistance (correct)
  • Stroke volume and diaphragmatic movement
  • Venous return and kidney function

How is cardiac output calculated?

  • CO = PA - PV
  • CO = HR x SV (correct)
  • CO = SV/HF
  • CO = HR + SV

What role does aldosterone play in mean arterial pressure?

  • Decreases blood volume and pressure
  • Dilates arterioles to lower resistance
  • Increases reabsorption of salt and water (correct)
  • Regulates heart rate directly

What happens to blood flow in relation to total resistance?

<p>Flow decreases as resistance increases (D)</p> Signup and view all the answers

Which factor influences stroke volume?

<p>Force of contraction in the ventricular myocardium (C)</p> Signup and view all the answers

Which system controls blood volume and peripheral resistance?

<p>Renin-angiotensin-aldosterone system (RAAS) (D)</p> Signup and view all the answers

What governs local blood flow to tissues?

<p>Local mediators (B)</p> Signup and view all the answers

How is the distribution of blood related to mean arterial pressure?

<p>Changes in blood distribution can alter resistance (D)</p> Signup and view all the answers

Which of the following is directly proportional to flow?

<p>Pressure gradient (Pa - Pv) (C)</p> Signup and view all the answers

Which mechanism aids venous return?

<p>Skeletal muscle pump (C)</p> Signup and view all the answers

What is the definition of pulse pressure?

<p>The difference between systolic and diastolic blood pressure. (D)</p> Signup and view all the answers

Which sound is first heard at the systolic pressure when measuring blood pressure?

<p>Snapping sound. (C)</p> Signup and view all the answers

What is the mean arterial pressure (MAP) for a blood pressure reading of 120/80 mmHg?

<p>93.33 mmHg (B)</p> Signup and view all the answers

Which factor most significantly affects pulse pressure?

<p>Stroke volume (C)</p> Signup and view all the answers

What happens to blood pressure as it flows through the circulatory system?

<p>It decreases continuously. (B)</p> Signup and view all the answers

What is indicated by the silence heard when cuff pressure drops below diastolic blood pressure?

<p>Diastolic blood pressure. (D)</p> Signup and view all the answers

How is mean arterial pressure (MAP) most accurately described?

<p>It represents the time-average pressure in the arteries. (D)</p> Signup and view all the answers

Which of the following is NOT a characteristic of the Korotkoff sounds?

<p>The first sound is the loudest. (D)</p> Signup and view all the answers

What is the primary role of baroreceptors in the body?

<p>To regulate blood pressure (D)</p> Signup and view all the answers

Which mechanism is responsible for a fast response to changes in blood pressure?

<p>Baroreceptor reflex (A)</p> Signup and view all the answers

Which of the following is NOT a component of the baroreceptor reflex?

<p>Hormonal secretion (D)</p> Signup and view all the answers

In the context of the baroreceptor reflex, what does an increase in blood pressure trigger?

<p>Parasympathetic response (B)</p> Signup and view all the answers

What systemic response occurs due to activation of sympathetic neurons in the baroreceptor reflex?

<p>Increased heart rate (B)</p> Signup and view all the answers

How does the body compensate for low blood pressure during orthostatic hypotension?

<p>Increased cardiac output (D)</p> Signup and view all the answers

What happens in the baroreceptor reflex when there is a sudden drop in blood pressure?

<p>Compensatory sympathetic stimulation increases (D)</p> Signup and view all the answers

Which of the following actions is a result of the baroreceptor reflex in response to increased blood pressure?

<p>Excretion of fluid in urine (D)</p> Signup and view all the answers

What role do medullary cardiovascular control centers play in the baroreceptor reflex?

<p>They integrate sensory information and coordinate responses. (B)</p> Signup and view all the answers

What response occurs in the cardiovascular system during fast responses to increased blood pressure?

<p>Vasodilation of the arteries (A)</p> Signup and view all the answers

Flashcards

Blood Pressure

The force exerted by circulating blood on the walls of blood vessels.

Systolic Pressure

The pressure in the arteries during the contraction of the heart.

Diastolic Pressure

The pressure in the arteries when the heart is at rest between beats.

Pulse Pressure

The difference between systolic and diastolic pressures.

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Mean Arterial Pressure (MAP)

The average arterial pressure during a single cardiac cycle.

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Korotkoff Sounds

Sounds heard during the measurement of blood pressure using a stethoscope.

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Pressure Points

Locations on the body where the pulse can be easily felt.

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Factors Affecting Pulse Pressure

Conditions like stroke volume, afterload, and cardiac output influence pulse pressure.

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Cardiac Output (CO)

The volume of blood the heart pumps per minute, calculated as heart rate multiplied by stroke volume.

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Stroke Volume (SV)

The amount of blood pumped by the left ventricle of the heart in one contraction.

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Total Resistance

The overall resistance to blood flow in the circulatory system, affected by the diameter of arterioles.

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Arteriolar Diameter

The width of arterioles, which directly influences resistance and blood flow to tissues.

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Renin-Angiotensin-Aldosterone System (RAAS)

A hormone system that regulates blood pressure and fluid balance by controlling blood volume and peripheral resistance.

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Sympathetic Innervation

The part of the autonomic nervous system that increases heart rate and blood pressure during stress or excitement.

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Parasympathetic Innervation

The part of the autonomic nervous system that decreases heart rate and promotes relaxation.

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Aldosterone

A hormone produced by the adrenal cortex that promotes sodium and water retention, increasing blood volume.

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Blood Pressure Gradient

The difference in pressure between two points in the circulatory system driving blood flow.

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Baroreceptors

Sensory receptors that detect changes in blood pressure.

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Fast Response Mechanism

Immediate adjustment of cardiovascular system in response to blood pressure changes.

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Slow Response Mechanism

Long-term regulation of blood pressure primarily by kidneys.

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Natriuresis

The excretion of sodium in the urine, lowering blood volume and pressure.

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Cardiovascular Control Center

Part of the brain that integrates sensory input to regulate heart and blood vessel function.

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Efferent Path

The pathway taken by signals from the integrating center to an effector.

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Vasodilation

The widening of blood vessels to decrease blood pressure.

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Sympathetic Neurons

Nerve cells that promote fight or flight responses, increasing heart rate and blood pressure.

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Orthostatic Hypotension

A drop in blood pressure when standing up quickly, leading to dizziness.

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Study Notes

Blood Pressure

  • Blood pressure is the force exerted by blood against the walls of blood vessels
  • Measured using a sphygmomanometer and stethoscope
  • Highest in arteries, decreasing as it flows through the circulatory system
  • Systolic pressure: pressure when the heart contracts
  • Diastolic pressure: pressure when the heart relaxes
  • Pulse pressure: difference between systolic and diastolic pressures
  • Mean arterial pressure (MAP): average pressure over the cardiac cycle
  • Formula for MAP: (2/3 x diastolic pressure) + (1/3 x systolic pressure)
  • Normal blood pressure: 120/80 mmHg

Measuring Blood Pressure

  • A blood pressure cuff is inflated to stop blood flow in an artery (e.g., brachial artery)
  • A stethoscope is used to listen for sounds (Korotkoff sounds) as the cuff pressure is released.
  • Systolic pressure: first sound heard
  • Diastolic pressure: last sound heard
  • The five Korotkoff sounds:
    • First sound: tapping, repetitive clear sounds - systolic
    • Second to fourth sounds: murmurs
    • Fifth/final sound: crisp, loud sounds-diastolic

Pulse

  • Pulse is a wave of pressure produced by the blood entering the arteries during systole
  • Monitored at pressure points where the pulse is easily palpable
  • Examples: temporal, facial, carotid, brachial, radial, femoral, popliteal, posterior tibial, dorsalis pedis arteries

Factors affecting Mean Arterial Pressure

  • Cardiac Output (CO)
    • Heart Rate (HR): rate of heart contractions
    • Stroke Volume (SV): amount of blood pumped per beat
  • Peripheral Resistance (PR): opposition to blood flow in the arteries
    • Arteriolar diameter: a key determinant of PR
  • Blood Volume: total amount of blood in the body
    • Includes fluid intake and fluid loss
  • Factors Influencing Blood Volume Regulation and Control
  • Neural control of heart rate and stroke volume
  • Vascular smooth muscle responses
  • Hormonal control and regulation
  • Renin-angiotensin-aldosterone system (RAAS): control of blood volume
  • Baroreceptors and regulation of blood pressure

Control of Blood Pressure

  • Fast response: baroreceptor reflex (within a few heartbeats)
    • Baroreceptors in the carotid sinus and aortic arch detect pressure changes
  • Slow response: renin-angiotensin-aldosterone system
    • A feedback loop that regulates blood volume
  • Other factors impacting blood pressure (e.g., hormones and chemicals):
    • Hormones: Antidiuretic Hormone (ADH), Epinephrine, Norepinephrine
    • Chemicals: Local mediators
  • Mechanisms for regulating peripheral resistance:
    • Vasodilation and vasoconstriction

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