30 Questions
What is the percentage of water in blood plasma?
90%
What is the primary function of plasma proteins?
To carry out a number of different functions
Which of the following is NOT a characteristic of plasma proteins?
They are all simple proteins
What is the purpose of zone electrophoresis in plasma protein measurement?
To separate and estimate protein fractions
What is the name of the proteins that can be divided into two large classes based on the precipitate formed in a solution half saturated with ammonium sulfate?
Albumins and Globulins
What is the name of the process that prevents blood clotting in plasma?
Anticoagulation
What is the typical molecular weight of C-reactive protein?
120kD
What is the primary function of C-reactive protein in the immune system?
Activation of the complement cascade
What is the effect of sulfonamides on bilirubin in infants?
Release of unconjugated bilirubin from albumin
What is the typical time frame for CRP levels to rise above normal limits in acute inflammation?
Within 6 hours
What is the primary function of plasmin in the body?
Hydrolysis of fibrin
What happens to albumin synthesis in cases of liver disease or starvation?
It decreases
What is the result of two drugs with the same affinity for albumin being administered together?
Displacement of one drug by the other
What is the site of plasminogen synthesis?
Liver
What is the clinical importance of CRP levels?
Predicting the risk of coronary heart disease
What is the only cause of hyperalbuminemia?
Dehydration
What is the effect of hypoalbuminemia on calcium levels?
Decreased calcium levels
What is the test used to detect albumin in urine?
All of the above
What is the primary function of α1- protease inhibitor (API)?
To inhibit the activity of proteases, particularly elastase
What is the normal concentration of α1- fetoprotein (AFP) in a healthy adult?
< 1µg/100ml
What is the approximate molecular weight of retinol binding protein (RBP)?
21 kD
What is the half-life of retinol binding protein (RBP)?
12 hours
What is the function of α1- acid glycoprotein (AAG)?
Unknown function
What can cause oxidation of Met358 to methionine sulfoxide and inactivate α1-AT?
Smoking
What is the primary function of haemopexin?
To bind haem formed from the breakdown of Hb and other haemoproteins
What is the molecular weight of Complement C1q?
400,000
What is the term for proteins that decrease in concentration after trauma or infection?
Negative acute phase reactants
What is the normal level of haemopexin in adults?
0.5-1.0 gm/L
What is the region of the IgG or IgM where Complement C1q binds?
Fc region
What is the condition where high levels of haemopexin are found?
Diabetes mellitus
Learn about the different components of blood plasma, including water, plasma proteins, electrolytes, nutrients, hormones, wastes, and blood gases. This quiz covers the basics of plasma composition and its various components.
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