Blood Components and Functions

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Questions and Answers

If a patient has a condition that reduces their red bone marrow activity, which of the following blood components would be most affected?

  • Blood glucose levels
  • Plasma proteins
  • Hormone transport
  • Erythrocytes (correct)

A researcher is studying a cell's ability to differentiate into various blood cell types. Which type of cell should they focus on?

  • Megakaryocyte
  • Pluripotential stem cell (correct)
  • Erythrocyte
  • Myelocyte

Which of the following scenarios would likely result in an increased production of erythrocytes?

  • Undergoing a blood transfusion
  • Chronic lung disease (correct)
  • Experiencing a bacterial infection
  • Moving from a high altitude to a low altitude environment

A patient is diagnosed with a condition that impairs their ability to form blood clots. Which formed element is most likely deficient or malfunctioning?

<p>Platelets (A)</p>
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If a patient has a parasitic infection, which type of granulocyte would be expected to be elevated in their blood?

<p>Eosinophil (D)</p>
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A patient undergoing an allergic reaction would likely have an increase in the activity of which granulocyte?

<p>Basophils (A)</p>
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Why might a differential white blood cell count be ordered as part of a routine check-up?

<p>To identify and quantify each type of white blood cell (B)</p>
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In a patient with a chronic bacterial infection, which type of leukocyte would you expect to see an elevated count of?

<p>Neutrophils (B)</p>
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A researcher is investigating the production and development of monocytes. Which cell line should they focus on?

<p>Myeloid stem cell (A)</p>
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What role do plasma cells play in the body's defense mechanisms?

<p>Secreting antibodies (D)</p>
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A patient's blood smear shows an increased presence of cells with a horseshoe-shaped nucleus. This is indicative of an increase in which type of cell?

<p>Monocyte (B)</p>
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If Erythropoiesis increased above normal, what immature blood cell, released from bone marrow, would likely be elevated in a peripheral blood smear?

<p>Reticulocyte (A)</p>
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If a hypothetical drug impairs maturation of T lymphocytes, which organ is most likely being affected by the drug?

<p>Thymus (B)</p>
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What impact would significant damage to a patient’s red bone marrow likely have on the number of circulating reticulocytes?

<p>Cause a decrease in the number of reticulocytes (A)</p>
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Which scenario accurately describes how basophils contribute to the inflammatory response?

<p>Basophils release histamine and heparin (D)</p>
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How does hemoglobin contribute to the function of erythrocytes?

<p>By transporting oxygen and carbon dioxide (C)</p>
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A patient's compromised immune system struggles to produce enough antibodies after vaccination. What does this suggest about their immune cell function?

<p>Impaired function of plasma cells (C)</p>
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How would a deficiency in platelets impact the body's ability to respond to an injury such as a cut?

<p>Impaired blood clotting (B)</p>
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What cellular transformation can occur when monocytes migrate from the bloodstream into the tissues?

<p>They differentiate into macrophages (C)</p>
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How does the shape and structure of an erythrocyte enhance its primary function?

<p>The biconcave disc shape increases surface area for gas exchange (C)</p>
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Flashcards

Formed elements of blood

Erythrocytes (red blood cells), leukocytes (white blood cells), and platelets.

Main function of erythrocytes

Transporting oxygen from the lungs to the body's tissues and carbon dioxide from the tissues back to the lungs.

Liquid matrix of blood

The liquid component of blood in which blood cells are suspended. It carries nutrients, hormones, and waste products.

Hemopoiesis location in adults

In adults this occurs in the red bone marrow, primarily in flat bones like the sternum, ribs, and pelvis.

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Pluripotential stem cell

A stem cell that can differentiate into any type of blood cell.

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Granulocyte

A type of white blood cell characterized by granules in their cytoplasm; example: neutrophil.

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Average life span of erythrocytes

Approximately 120 days.

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Platelet precursor

Megakaryocytes.

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Function of platelets

Platelets are responsible for initiating blood clot formation.

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Eosinophil characteristics

Eosinophils have a bilobed nucleus and pink granules.

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Allergic reaction granulocyte

Basophils are involved in allergic reactions by releasing histamine and heparin.

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Most abundant leukocyte

Neutrophils constitute the largest percentage, typically 50-70%, of leukocytes in the blood.

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Monocyte/Neutrophil cell line

Myeloid stem cell.

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Horseshoe-shaped nucleus cell

Monocytes have a horseshoe-shaped nucleus.

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Lymphocyte response to antigens

Plasma cells.

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Plasma cell product

Plasma cells produce antibodies.

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Phagocytic cells

Neutrophils are phagocytic, meaning they engulf and digest bacteria and cellular debris.

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Basophilic granule color

Dark blue or brown.

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Anti-parasitic granulocyte

Eosinophils destroy helminthic parasites (worms).

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Granulocyte precursor

Myeloblast.

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Study Notes

  • Blood's formed elements include erythrocytes, leukocytes, and platelets.
  • Erythrocytes' main function is transporting oxygen and carbon dioxide.
  • Plasma is the liquid matrix of blood.
  • Hemopoiesis occurs in red bone marrow of adults.
  • Pluripotential stem cells give rise to all blood cell types.
  • Neutrophils are granulocytes.
  • Erythrocytes have an average life span of 120 days.
  • Platelets originate from megakaryocytes.
  • Platelets function to form blood clots.
  • Eosinophils have a bilobed nucleus and pink granules.
  • Basophils are involved in allergic reactions.
  • Neutrophils constitute the largest percentage of leukocytes in the blood.
  • Myeloid stem cells give rise to monocytes and neutrophils.
  • Monocytes have a horseshoe-shaped nucleus.
  • Lymphocytes form plasma cells in response to antigens.
  • Plasma cells produce antibodies.
  • Neutrophils are phagocytic cells.
  • Basophilic granules in basophils are dark blue or brown.
  • Eosinophils destroy helminthic parasites.
  • Myeloblast is the first recognizable precursor of granulocytes.
  • Hemoglobin gives the erythrocyte its red color.
  • Reticulocytes are immature erythrocytes without a nucleus.
  • Megakaryocytes have demarcation membranes.
  • Reticulocytes are the final stage of erythrocyte development before maturity.
  • Monocytes become macrophages in tissue.
  • The thymus gland stimulates T lymphocyte maturation.
  • Neutrophils have a multilobed nucleus and clear cytoplasm.
  • Basophils contain histamine and heparin.
  • Lymphocytes have no cytoplasmic granules and a large nucleus.
  • Eosinophils constitute 2–4% of blood leukocytes.

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