Blood Clotting Mechanism

The human body protects against loss of blood through the ______ mechanism.

______ is the initial response when the vessel is injured.

Primary hemostasis involves processes such as vasoconstriction, platelet adhesion, platelet activation, and platelet ______.

Secondary hemostasis involves the activation of ______ factors.

The conversion of prothrombin to ______ is a key step in secondary hemostasis.

The conversion of fibrinogen to ______ is essential for forming a stable blood clot.

______ is released by damaged endothelium and is responsible for vasoconstriction.

______ factor, ATP and inflammatory mediators are released from damaged endothelial cells that are responsible for platelet adhesion, activation, and aggregation.

TF, or ______ factor, is responsible for Factor Xa activation.

The tests of hemorrhagic disorder include platelet count, hess's tests and ______ time.

The coagulation factors act together to form ______ and stop loss of blood.

Normal ______ Mechanism ensures the balance between clot formation and dissolution.

Following vessel injury, the immediate local response aimed at reducing blood flow is ______.

In addition to vasoconstriction and platelet adhesion, what other process is involved in primary hemostasis? ______ activation

The activation of clotting factors ultimately leads to the formation of a ______ clot.

The role of thrombin is to convert fibrinogen into ______, which forms the structural meshwork of a blood clot.

What substance released by damaged endothelial cells not only causes vasoconstriction but also recruits platelets to the injury site? ______

Which factor, released by damaged endothelium, plays a critical role in mediating platelet adhesion to the subendothelial matrix? ______ factor

The activation of factor X by tissue factor is a crucial step in what process concerning hemostasis? ______ cascade.

Besides platelet count, which additional test evaluates the effectiveness of platelet plug formation in vivo? ______ time