Podcast
Questions and Answers
What is the grading system for polychromatophilia based on the number of red blood cells per field?
What is the grading system for polychromatophilia based on the number of red blood cells per field?
Which feature is characteristic of red blood cells with Hb H bodies?
Which feature is characteristic of red blood cells with Hb H bodies?
What staining method reveals pink dots scattered in the cytoplasm of red blood cells?
What staining method reveals pink dots scattered in the cytoplasm of red blood cells?
Which condition is associated with increased serum protein, potentially leading to rouleaux formation?
Which condition is associated with increased serum protein, potentially leading to rouleaux formation?
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What is the grading for schistocytes in the red cell morphology chart?
What is the grading for schistocytes in the red cell morphology chart?
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What type of red blood cells is indicated by the presence of Schuffner's dots?
What type of red blood cells is indicated by the presence of Schuffner's dots?
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Which of the following conditions can falsely indicate the presence of rouleaux formation?
Which of the following conditions can falsely indicate the presence of rouleaux formation?
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What is the significance of a 3+ grading for poikilocytosis?
What is the significance of a 3+ grading for poikilocytosis?
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What could cause the formation of target cells in blood samples?
What could cause the formation of target cells in blood samples?
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Bentz Jones Protein is associated with rouleaux formation related to which condition?
Bentz Jones Protein is associated with rouleaux formation related to which condition?
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Study Notes
Parasites
- Protozoa/Protozoans are examples
- Malaria is an example
- Schuffner's dots (eosinophilic stippling)
- Babesia spp.
Red Blood Cell Morphology Grading Chart
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Grading of Red Blood Cell Morphology
- 1+ = 1 to 5 per field
- 2+ = 6 to 10 per field
- 3+ = greater than 10 per field
-
Polychromatophilia:
- 1+ = 3 to 10 per field
- 2+ = 11 to 20 per field
- 3+ = greater than 20 per field
-
Helmet cells (helmet-shaped schistocytes)
- 1+ = 1 to 5 per field
- 2+ = 6 to 10 per field
- 3+ = more than 10 per field
-
Dacryocytes (teardrop cells)
- 1+ = 1 to 5 per field
- 2+ = 6 to 10 per field
- 3+ = more than 10 per field
-
Acanthocytes (thorn or spur cells)
- 1+ = 1 to 5 per field
- 2+ = 6 to 10 per field
- 3+ = more than 10 per field
-
Schistocytes (fragmented RBCs)
- 1+ = 1 to 5 per field
- 2+ = 6 to 10 per field
- 3+ = more than 10 per field
-
Spherocytes
- 1+ = 3 to 10 per field
- 2+ = 11 to 20 per field
- 3+ = more than 20 per field
-
Ovalocytes
- 1+ = 3 to 10 per field
- 2+ = 11 to 20 per field
- 3+ = greater than 20 per field
-
Elliptocytes
- 1+ = 3 to 10 per field
- 2+ = 11 to 20 per field
- 3+ = greater than 20 per field
-
Burr cells
- 1+ = 3 to 10 per field
- 2+ = 11 to 20 per field
- 3+ = greater than 20 per field
-
Bizarre-shaped RBC
- 1+ = 3 to 10 per field
- 2+ = 11 to 20 per field
- 3+ = greater than 20 per field
-
Target cells (codocytes/leptocytes/bull's eye cells)
- 1+ = 3 to 10 per field
- 2+ = 11 to 20 per field
- 3+ = greater than 20 per field
-
Mexican hat cells/Greek helmet cells/platycytes
- 1+ = 3 to 10 per field
- 2+ = 11 to 20 per field
- 3+ = more than 20 per field
-
Stomatocytes (mouth cells)
-
Rouleaux (aka: Pseudo agglutination)
- 1+ = aggregates of 3 to 4 RBCs
- 2+ = aggregates of 5 to 10 RBCs
- 3+ = many aggregates with only a few free RBCs
Additional Notes
- Rouleaux formation is associated with increased serum globulin or fibrinogen
- Rouleaux formation may be observed in Multiple Myeloma (now called Plasma cell myeloma/Kahler's disease) myelomatosis
- Rouleaux is sometimes misreported because of overlapping cells in the thick portion of the blood smear
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Description
Test your knowledge on parasitic protozoa such as malaria and their identification through red blood cell morphology. This quiz covers grading charts for various types of abnormal red blood cells associated with parasitic infections. Understand the key features and classifications of these blood cell morphologies.
