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Questions and Answers
What is the main difference between protein-bound drugs and unbound drugs?
What is the main difference between protein-bound drugs and unbound drugs?
Which proteins do acidic drugs primarily bind to in the plasma?
Which proteins do acidic drugs primarily bind to in the plasma?
In the context of plasma protein binding, what does it mean when two drugs bind at the same site of the protein and are administered together?
In the context of plasma protein binding, what does it mean when two drugs bind at the same site of the protein and are administered together?
What factor should be considered when treating an elderly person with a basic drug?
What factor should be considered when treating an elderly person with a basic drug?
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What happens to the protein-bound drug once the free drug enters the target tissue?
What happens to the protein-bound drug once the free drug enters the target tissue?
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What effect does a diseased state have on the effectiveness of a drug that undergoes plasma protein binding?
What effect does a diseased state have on the effectiveness of a drug that undergoes plasma protein binding?
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Which type of drugs primarily bind to α1 – acid glycoprotein in plasma?
Which type of drugs primarily bind to α1 – acid glycoprotein in plasma?
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How is the bound drug different from the unbound drug in terms of pharmacological activity?
How is the bound drug different from the unbound drug in terms of pharmacological activity?
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Why is it important to consider protein binding when administering drugs?
Why is it important to consider protein binding when administering drugs?
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What role does equilibrium play between protein-bound and free drug in target tissues?
What role does equilibrium play between protein-bound and free drug in target tissues?
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