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Blood Bank Midterms: RH Blood Group System Quiz

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Questions and Answers

What is the purpose of the six-digit number system adopted by the International Society of Blood Transfusion (ISBT) for blood group systems?

To provide a unique identifier for each antigen within a blood group system (correct)
To represent the antigenic specificity of each blood group system
To standardize the classification of blood group systems across different countries
To simplify the naming of blood group systems

What is the significance of the Rh protein in the Rh blood group system?

The Rh protein is encoded by a single gene, RHD
The Rh protein carries the D, C/c, and E/e epitopes (correct)
The Rh protein is not part of the red cell membrane cytoskeleton
The Rh protein is a glycosylated transmembrane protein

Which Rh phenotype has the greatest number of D antigen sites on the red blood cells?

Dd
R1R1
R2R2
D-- (correct)

How do Rh antibodies typically react?

Rh antibodies are IgG and react optimally at 37°C or with the addition of antiglobulin reagents (A) Signup and view all the answers

What is the consequence of the absence of Rh antigens?

Increased red cell membrane permeability leading to stomatocytosis (C) Signup and view all the answers

Which gene encodes the Rh proteins that carry the C/c and E/e epitopes?

RHCE (A) Signup and view all the answers

Which of the following is NOT a characteristic of the Rh blood group system?

Antigens are produced by a single gene (B) Signup and view all the answers

The $D$ antigen is considered the most important antigen in the Rh blood group system. What is the significance of the $D$ antigen?

The $D$ antigen is used in the determination of $Rh$ status, with $D$ positive individuals being $Rh$ positive (D) Signup and view all the answers

What is the purpose of anti-$D$ antisera in the Rh blood group system?

To detect the presence of the $D$ antigen and determine Rh status (D) Signup and view all the answers

What is the relationship between the ABO blood group system and the Rh blood group system?

The ABO and Rh systems are completely independent and unrelated (D) Signup and view all the answers

What is the significance of the Rh associated glycoprotein (RhAG) in the Rh blood group system?

RhAG is a co-expressor of the Rh antigens on the red blood cell surface (D) Signup and view all the answers

Which of the following is NOT a key aspect of the nomenclature used to describe the Rh blood group system?

The presence or absence of the ABO precursor substance (B) Signup and view all the answers

What was the likely cause of the acute hemolytic transfusion reaction experienced by the recipient after receiving a blood transfusion from her husband?

The recipient lacked an antigen present on the donor's red blood cells, and had developed antibodies against this antigen during a previous pregnancy. (C) Signup and view all the answers

Which of the following statements about the Rh blood group system is true?

The Rh system includes the D, C, c, E, and e antigens. (B) Signup and view all the answers

What is the significance of the term 'd' in the Rh blood group system?

It represents the absence or deletion of the D antigen. (A) Signup and view all the answers

What is the significance of the antibody discovered by Landsteiner and Wiener?

It was used to identify the different antigens in the Rh blood group system. (D) Signup and view all the answers

According to the Fisher-Race proposal, how many Rh genes does each person inherit from each parent?

Three, representing the D, C, and E antigens. (C) Signup and view all the answers

What percentage of human red blood cells was agglutinated by the antibody named 'Anti-Rh'?

85% (C) Signup and view all the answers

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