Blood Bank Midterms: RH Blood Group System Quiz
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Questions and Answers

What is the purpose of the six-digit number system adopted by the International Society of Blood Transfusion (ISBT) for blood group systems?

  • To provide a unique identifier for each antigen within a blood group system (correct)
  • To represent the antigenic specificity of each blood group system
  • To standardize the classification of blood group systems across different countries
  • To simplify the naming of blood group systems
  • What is the significance of the Rh protein in the Rh blood group system?

  • The Rh protein is encoded by a single gene, RHD
  • The Rh protein carries the D, C/c, and E/e epitopes (correct)
  • The Rh protein is not part of the red cell membrane cytoskeleton
  • The Rh protein is a glycosylated transmembrane protein
  • Which Rh phenotype has the greatest number of D antigen sites on the red blood cells?

  • Dd
  • R1R1
  • R2R2
  • D-- (correct)
  • How do Rh antibodies typically react?

    <p>Rh antibodies are IgG and react optimally at 37°C or with the addition of antiglobulin reagents</p> Signup and view all the answers

    What is the consequence of the absence of Rh antigens?

    <p>Increased red cell membrane permeability leading to stomatocytosis</p> Signup and view all the answers

    Which gene encodes the Rh proteins that carry the C/c and E/e epitopes?

    <p>RHCE</p> Signup and view all the answers

    Which of the following is NOT a characteristic of the Rh blood group system?

    <p>Antigens are produced by a single gene</p> Signup and view all the answers

    The $D$ antigen is considered the most important antigen in the Rh blood group system. What is the significance of the $D$ antigen?

    <p>The $D$ antigen is used in the determination of $Rh$ status, with $D$ positive individuals being $Rh$ positive</p> Signup and view all the answers

    What is the purpose of anti-$D$ antisera in the Rh blood group system?

    <p>To detect the presence of the $D$ antigen and determine Rh status</p> Signup and view all the answers

    What is the relationship between the ABO blood group system and the Rh blood group system?

    <p>The ABO and Rh systems are completely independent and unrelated</p> Signup and view all the answers

    What is the significance of the Rh associated glycoprotein (RhAG) in the Rh blood group system?

    <p>RhAG is a co-expressor of the Rh antigens on the red blood cell surface</p> Signup and view all the answers

    Which of the following is NOT a key aspect of the nomenclature used to describe the Rh blood group system?

    <p>The presence or absence of the ABO precursor substance</p> Signup and view all the answers

    What was the likely cause of the acute hemolytic transfusion reaction experienced by the recipient after receiving a blood transfusion from her husband?

    <p>The recipient lacked an antigen present on the donor's red blood cells, and had developed antibodies against this antigen during a previous pregnancy.</p> Signup and view all the answers

    Which of the following statements about the Rh blood group system is true?

    <p>The Rh system includes the D, C, c, E, and e antigens.</p> Signup and view all the answers

    What is the significance of the term 'd' in the Rh blood group system?

    <p>It represents the absence or deletion of the D antigen.</p> Signup and view all the answers

    What is the significance of the antibody discovered by Landsteiner and Wiener?

    <p>It was used to identify the different antigens in the Rh blood group system.</p> Signup and view all the answers

    According to the Fisher-Race proposal, how many Rh genes does each person inherit from each parent?

    <p>Three, representing the D, C, and E antigens.</p> Signup and view all the answers

    What percentage of human red blood cells was agglutinated by the antibody named 'Anti-Rh'?

    <p>85%</p> Signup and view all the answers

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